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  1. Masood M, Masood Y, Saub R, Newton JT
    J Public Health Dent, 2014;74(1):13-20.
    PMID: 22994869 DOI: 10.1111/j.1752-7325.2012.00374.x
    Demand and use for oral health-related quality of life (OHRQoL) instruments have increased in recent years in both research and clinical settings. These instruments can be used to measure patient's health status or detect changes in a patient's health status in response to an intervention or changes in disease trajectory. Ensuring universal acceptance of these measures requires easy interpretation of its scores for clinicians, researchers, and patients. The most important way of describing and interpreting this significance of changes in OHRQoL is through the establishment of minimal important difference (MID). The minimally important difference represents the smallest improvement considered worthwhile by a patient. A comprehensive search of published literature identified only 12 published articles on establishment of MID for OHRQoL measures. This scarcity of published studies on MID encourages the need of appropriate interpretation and describing patient satisfaction in reference to that treatment using MID. Anchor- and distribution-based methods are the two general approaches that have been proposed and recommended to interpret differences or changes in OHRQoL. Both of these methods of determining the MID have specific shortcomings; therefore, it is proposed to adopt triangulation approaches in which the methods are combined. The objective of this review is to summarize the need for, importance of, and recommendations for methods of establishing MID for OHRQoL measures.
    Matched MeSH terms: Quality of Life*
  2. Chongmelaxme B, Lee S, Dhippayom T, Saokaew S, Chaiyakunapruk N, Dilokthornsakul P
    J Allergy Clin Immunol Pract, 2019 Jan;7(1):199-216.e11.
    PMID: 30055283 DOI: 10.1016/j.jaip.2018.07.015
    BACKGROUND: Telemedicine is increasingly used to improve health outcomes in asthma. However, it is still inconclusive which telemedicine works effectively.

    OBJECTIVE: This study aimed to determine the effects of telemedicine on asthma control and the quality of life in adults.

    METHODS: An electronic search was performed from the inception to March 2018 on the following databases: Cochrane CENTRAL, CINAHL, ClinicalTrials.gov, EMBASE, PubMed, and Scopus. Randomized controlled trials that assessed the effects of telemedicine in adults with asthma were included in this analysis, and the outcomes of interest were levels of asthma control and quality of life. Random-effects model meta-analyses were performed.

    RESULTS: A total of 22 studies (10,281 participants) were included. Each of 11 studies investigated the effects of single-telemedicine and combined-telemedicine (combinations of telemedicine approaches), and the meta-analyses showed that combined tele-case management could significantly improve asthma control compared with usual care (standardized mean difference [SMD] = 0.78; 95% confidence interval [CI]: 0.56, 1.01). Combined tele-case management and tele-consultation (SMD = 0.52 [95% CI: 0.13, 0.91]) and combined tele-consultation (SMD = 0.28 [95% CI: 0.13, 0.44]) also significantly improved asthma outcomes, but to a lesser degree. In addition, combined tele-case management (SMD = 0.59 [95% CI: 0.31, 0.88]) was the most effective telemedicine for improving quality of life, followed by combined tele-case management and tele-consultation (SMD = 0.31 [95% CI: 0.03, 0.59]), tele-case management (SMD = 0.30 [95% CI: 0.05, 0.55]), and combined tele-consultation (SMD = 0.27 [95% CI: 0.11, 0.43]), respectively.

    CONCLUSIONS: Combined-telemedicine involving tele-case management or tele-consultation appear to be effective telemedicine interventions to improve asthma control and quality of life in adults. Our findings are expected to provide health care professionals with current evidence of the effects of telemedicine on asthma control and patients' quality of life.
    Matched MeSH terms: Quality of Life*
  3. Arunachalam S, Sharan J
    Am J Orthod Dentofacial Orthop, 2018 02;153(2):168-169.
    PMID: 29407490 DOI: 10.1016/j.ajodo.2017.11.013
    Matched MeSH terms: Quality of Life*
  4. Ezat WP, Noraziani K, Sabrizan O
    Asian Pac. J. Cancer Prev., 2012;13(3):1069-75.
    PMID: 22631640
    There are an almost infinite number of states of health, all with differing qualities that can be affected by many factors. Each aspect of health has many components which contribute to multidimensionality. Cancer and its' related issues surrounding the treatment plan contribute to the variety of changes of quality of life of cancer patients throughout their life. The objective of this article was to provide an overview of some of the issues that can affect their quality of life and initiatives towards successful care in Malaysia by reviewing relevant reports and articles. The current strategies can be further strengthened by prevention of cancer while improving quality of service to cancer patients.
    Matched MeSH terms: Quality of Life*
  5. Syed IA, Syed Sulaiman SA, Hassali MA, Lee CK
    Health Expect, 2015 Oct;18(5):1363-70.
    PMID: 24010818 DOI: 10.1111/hex.12116
    BACKGROUND: Health-related quality of life (HRQoL) is increasingly recognized as an important outcome and as a complement to traditional biological end points of diseases such as mortality. Unless there is a complete cure available for HIV/AIDS, development and implementation of a reliable and valid cross cultural quality of life measure is necessary to assess not only the physical and medical needs of HIV/AIDS people, but their psychological, social, environmental, and spiritual areas of life.
    METHODS: A qualitative exploration of HIV/AIDS patients' understanding, perceptions and expectations will be carried out with the help of semi structured interview guide by in depth interviews, while quantitative assessment of patient reported adverse drug reactions and their impact on health related quality of life will be carried out by using data collection tool comprising patient demographics, SF-12, Naranjo scale, and a clinical data sheet.
    RESULTS/OUTCOMES: The findings may serve as baseline QOL data of people living with HIV/AIDS in Malaysia and also a source data to aid construction of management plan to improve HIV/AIDS patients' QOL. It will also provide basic information about HIV/AIDS patients' perceptions, expectations and believes towards HIV/AIDS and its treatment which may help in designing strategies to enhance patients' awareness which in turn can help in addressing issues related to compliance and adherence.
    KEYWORDS: HIV/AIDS; adverse drug reactions; patients' perspective; quality of life
    Matched MeSH terms: Quality of Life*
  6. Raihana, Z., Farah Nabilah, A.M.
    MyJurnal
    Most studies done in the past on factors affecting academic performance did not touch on quality of life factor. Also, most studies only used correlation and regression analysis. Not many studies used classification analysis. Hence, this study aimed to classify students based on quality of life and academic performance. Students’ quality of life was measured by using WHOQOL-BREF questionnaire which consists of five quality of life domains namely physical health, psychological health, social relationship, environment and overall quality of life whereas the academic performances were represented by cumulative grade point average (CGPA). The selected sample for this study was 60 Universiti Teknologi MARA (UiTM) Perlis students from Bachelor of Science (Hons.) Management Mathematics program. This study applied support vector machine (SVM) method for classifying the students. The results for each quality of life domain showed that students with both low and high academic performance were classified into high academic performance class. The same result was obtained when all domains were combined. All models showed high accuracy which implied that the classification made by SVM were strongly correct. The findings of this study demonstrated that quality of life plays an important role in students’ academic performance.
    Matched MeSH terms: Quality of Life*
  7. Lim R, Liong ML, Leong WS, Lau YK, Khan NAK, Yuen KH
    Urology, 2018 Feb;112:38-45.
    PMID: 29107131 DOI: 10.1016/j.urology.2017.10.019
    OBJECTIVE: To assess the impact of stress urinary incontinence (SUI) on individual components of quality of life (QoL) using both condition-specific and generic questionnaires, and to compare the results of the 2 instruments with a control group.

    METHODS: Women with or without SUI aged ≥21 years old were recruited. Subjects completed the International Consultation of Incontinence-Urinary Incontinence Short Form (ICIQ-UI-SF), International Consultation of Incontinence-Lower Urinary Tract Symptoms Quality of Life (ICIQ-LUTSqol), and EQ-5D questionnaires.

    RESULTS: A total of 120 women with SUI and 145 controls participated. The ICIQ-LUTSqol total score (mean ± standard deviation) was significantly higher in the SUI group (38.96 ± 10.28) compared with the control group (20.78 ± 2.73) (P 

    Matched MeSH terms: Quality of Life*
  8. Hamzaid H, Talib RA, Azizi NH, Maamor N, Reilly JJ, Wafa SW
    Int J Pediatr Obes, 2011 Oct;6(5-6):450-4.
    PMID: 21767214 DOI: 10.3109/17477166.2011.590206
    BACKGROUND:Quality of life (QoL) is impaired in childhood obesity, but the literature on this is all from Western countries. Aim. To test for impairment of QoL in obese children in Malaysia, using parent-reported and child-reported QoL.
    METHODS:Health-related Quality of Life was measured using the Paediatric Quality of Life Inventory version 4.0. Comparison of QoL between a community sample of 90 obese children (as defined by US CDC and Cole-IOTF definitions), median age 9.5 y (interquartile range [IQR] 8.6, 10.5 y) and 90 control children of healthy weight (BMI less than the 85th centile of US reference data), median age 10.0 y (IQR 9.6, 10.5 y). Children were matched pair-wise for age, gender, and ethnic group, and controls were recruited from schools in the same area as obese participants.
    RESULTS:For child self-report, the healthy weight group had significantly higher QoL for the physical (median 82.9, IQR 65.7, 90.6), and psychosocial domains (median, 73.3, IQR 64.4, 83.3), and total QoL (median 76.1, IQR 64.1, 84.8) compared to the obese group (median 67.2, IQR 59.4, 81.3; median 62.5, IQR 53.3, 75.4; median 60.9, IQR 50.8, 73.9; all p < 0.001). There were no significant differences between the obese and healthy weight group for parent-reported physical health, psychosocial health, or total QoL.
    CONCLUSION:Obese children in Malaysia have markedly poorer QoL than their peers, but this is not evident when parent reports of QoL are used.
    Study name: Malaysian Childhood Obesity Treatment Trial (MASCOT)
    Study site: Two primary schools, Kuala Lumpur, Malaysia
    Matched MeSH terms: Quality of Life*
  9. Ainuddin HA, Loh SY, Low WY, Sapihis M, Roslani AC
    Asian Pac. J. Cancer Prev., 2012;13(12):6289-94.
    PMID: 23464447
    BACKGROUND: Research evidence suggests a debilitating impact of the diagnosis of cancer on the quality of life of the afflicted individuals, their spouses and their families. However, relatively few studies have been carried out on the impact on the QOL of adolescents living with parents diagnosed with cancer. This paper presents a sub- analysis on the impact of parental cancer (colorectal, breast and lung) on adolescents.

    MATERIALS AND METHODS: This is a cross-sectional study on adolescents aged 13-18 years old. Upon ethical clearance obtained from UMMC Medical Ethics Committee, patients with colorectal, breast or lung cancer and their adolescent children were recruited from the Clinical Oncology Unit of University of Malaya Medical Centre. Respondents who gave consent completed a demographic questionnaire and the Pediatric Quality of Life Inventory, via the post, email, home visit or meetings at the clinics.

    RESULTS: 95 adolescents from 50 families responded, giving a response rate of 88 percent. The adolescent's mean age was 16 years (ranging between 13-18 years). Adolescents with parental cancer had the lowest mean score in emotional functioning (p<0.05). Male adolescents had significantly higher quality of life overall and in physical functioning compared to female adolescents. Adolescents with a father with cancer had better school functioning compared to adolescents whose mothers had cancer. Families with household income of RM 5000 and above have significantly better quality of life compared to families with lower household income.

    CONCLUSIONS: Adolescent sons and daughters of parents with a cancer diagnosis show lowered QOL, particularly with reference to emotional functioning and school performance. Addressing the needs of this young group has been slow and warrants special attention. Revisiting the risk and resilience factors of adolescents might also inform tailored programs to address the needs of this neglected adolescent population.

    Matched MeSH terms: Quality of Life/psychology*
  10. Hasanah CI, Naing L, Rahman ARA
    Med. J. Malaysia, 2003 Mar;58(1):79-88.
    PMID: 14556329 MyJurnal
    WHOQOL-100, a 100 items quality of life assessment by WHO is too lengthy to be applicable in researches where the quality of life is one of the many variables of interest. The abbreviated version with 26 items is more acceptable by subjects, especially those with illness. The generic and the abbreviated Malay version were given to subjects who were healthy and with illness. Results showed that the domain scores produced by WHOQOL-BREF correlate highly with that of WHOQOL-100. WHOQOL-BREF domain scores demonstrated good discriminant validity, construct validity, internal consistency and test-retest reliability. The study indicates that WHOQOL-BREF in its brevity offers a valid and reliable assessment of quality of life.
    Matched MeSH terms: Quality of Life*
  11. Chelvam P
    PMID: 8171292
    There is a need to define Quality of Life and to develop a practical method to measure objectively this aspect in gastrointestinal diseases. This has not been performed in any Asian population. It is proposed that this evaluation be part of future trials in Asia on the basis that Asian patients are culturally, socially and politically different from Westerners.
    Matched MeSH terms: Quality of Life*
  12. Tsutsumi A, Izutsu T, Ito A, Thornicroft G, Patel V, Minas H
    Lancet Psychiatry, 2015 Aug;2(8):679-680.
    PMID: 26249285 DOI: 10.1016/S2215-0366(15)00278-3
    Matched MeSH terms: Quality of Life/psychology*
  13. Mohd Adibi SMA, Chen NR, Azmir NA, Solahan N, Ismail A, Anuar AZ, et al.
    Med. J. Malaysia, 2013 Aug;68(4):315-22.
    PMID: 24145259 MyJurnal
    Hearing impairment in adolescents is a major public health problem. According to the World Health Organization (WHO) deafness and hearing impairment are common health problems throughout the world. Hearing impairment generally impairs emotional, social, communication and educational function. The aim of this study was to determine the correlation between duration of hearing aid use and improvements in the quality of life. The cross sectional study was conducted at Jalan Peel Primary Special School and Universiti Kebangsaan Malaysia Medical Center (UKMMC) from July 2010 until June 2011. A total of 21 students with hearing impairment involved in this study with mean age of 12.57 (10 to 19 years old). The subjects were divided into 2 groups: first-time hearing aid users and long standing hearing aid users. The hearing assessment was conducted in the first group and hearing aids were fitted. After 1 month hearing aid fitting, the questionnaires were distributed to both groups. Statistical analysis had showed no relation (p>0.05) between duration of hearing aid use and the improvement in the quality of life. However, regardless of the duration of hearing aid usage, there was improvement in the quality of life as shown by the scores of the questionnaires. In conclusion there was no significant relation between duration of hearing aid use and the improvement in the quality of life. Hearing aids were beneficial for hearing loss students regardless of the duration of the hearing aid usage.
    Matched MeSH terms: Quality of Life*
  14. Abdullah, N.S., Radzali, N.F.M., Saub, R., R.D. Vaithilingam,
    Ann Dent, 2013;20(2):16-23.
    MyJurnal
    To assess the oral health related quality of life
    (OHQoL) of a selected population of Malaysian adults and to compare the OHQoL by periodontal status. Material & Methods: This cross-sectional study comprises a convenient sampling of fifty subjects from the Primary Care Unit, Faculty of Dentistry, University of Malaya. OHQoL was assessed using the Malaysian version of Oral Health Impact Profile-14 (OHIP-14). Basic periodontal examination (BPE) was performed on all subjects to determine their periodontal status. Descriptive statistics and bivariate analysis were performed.
    Results: Psychological discomfort, physical pain and psychological disability domains were the most affected dimensions in this population. Subjects with income levels >RM2,500 had higher impacts on their OHQoL as compared to those from other income levels (p0.05).
    Conclusion: Subjects with high income levels had high impacts on their OHQoL. Those with periodontitis experienced higher impacts on their OHQoL as compared to those who had a healthy periodontium or gingivitis and affected a wide range of domains of quality of life.
    Matched MeSH terms: Quality of Life*
  15. Isa SN, Ishak I, Ab Rahman A, Mohd Saat NZ, Che Din N, Lubis SH, et al.
    Asian J Psychiatr, 2016 Oct;23:71-77.
    PMID: 27969083 DOI: 10.1016/j.ajp.2016.07.007
    Families caring for children with disabilities face particular challenges and demands compared to those caring for children without disabilities. Evidence suggests that there is considerable variation in how caregivers of children with disabilities adapt to their caregiving demands and stressors. The different adaptations to the children with disabilities may cause different impacts on the health and well-being of caregivers. This paper provides a brief overview of the literature on the impact of caring for children with disabilities on the health and quality of life of caregivers and the factors related to the health outcomes and quality of life. A literature search was conducted by using various electronic databases, including PsychINFO, ScienceDirect, ProQuest, and MEDLINE using specific key terms. Thirty-one articles published in peer-review journals from the last six years (2009-2014) were reviewed. Most of the studies were quantitative studies. Factors discussed that impact on caregivers' health and quality of life include the caregivers' sociodemographic background and child's disability-related factors. Several mediators and moderators including coping strategies, social support, parental stress, self-esteem and self-efficacy are described in this paper. This review highlighted the importance of these factors to better understand the complex nature of stress processes and the caregivers' adaptations to their children's disabilities.
    Matched MeSH terms: Quality of Life*
  16. Bakri NN, Tsakos G, Masood M
    Br Dent J, 2018 07 27;225(2):153-158.
    PMID: 30050198 DOI: 10.1038/sj.bdj.2018.529
    Objective: The primary objective of this study was to examine the association between smoking and oral health-related quality of life (OHRQoL) among dentate people aged 16 years and above in England.
    Methods: Cross-sectional study, based on the Adult Dental Health Survey (ADHS) 2009. ADHS 2009 involved data collection from 11,380 face-to-face interviews and 6,469 dental examinations from England, Wales and Northern Ireland. This study focuses on the dentate sample from England, consisting of 5,622 individuals who underwent dental examination. OHRQoL was measured by two indices; Oral Health Impact Profile-14 (OHIP-14) and Oral Impacts on Daily Performance (OIDP). Unadjusted and adjusted zero-inflated regression models were used. Adjustment was sequentially done for socio-demographics, clinical oral conditions and self-reported general health.
    Results: Prevalence of those who had never smoked, past smokers and current smokers were 45.6%, 35.3% and 19.2% respectively. Current smokers had considerably higher mean OHIP-14 and OIDP scores than non-smokers. There was a statistically significant association between smoking and OHRQoL (both OHIP-14 and OIDP) even in the fully adjusted models. Current smokers were more likely to report worse OHRQoL compared to those who had never smoked in both OHIP-14 and OIDP score. There was no statistically significant difference between past smokers with those who had never smoked in reporting OHIP-14 and OIDP. Among those reporting OHRQoL, there was a stepwise gradient risk of reporting no oral impact, where the probability was higher among those who had never smoked, followed by past smokers and current smokers both in OHIP-14 and OIDP.
    Conclusion: Smoking was independently associated with worse OHRQoL, even after adjusting for a range of socio-demographic factors, clinical oral conditions and self-reported general health.
    Matched MeSH terms: Quality of Life*
  17. Taha NA, Ibrahim MI, Rahman AF, Shafie AA, Rahman AH
    Value Health Reg Issues, 2012 May;1(1):82-86.
    PMID: 29702832 DOI: 10.1016/j.vhri.2012.03.006
    OBJECTIVES: To explore the validity and reliability of a disease-specific health-related quality-of-life questionnaire-the Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4)-in patients with schizophrenia in Malaysia.
    METHODS: A total of 222 outpatients with schizophrenia receiving treatment at the Universiti Kebangsaan Malaysia Medical Centre completed the SQLS-R4 in either the Malay or the English language. A generic self-report health-related quality-of-life measure-the EuroQoL group EuroQol five-dimensional questionnaire-and a measure of symptom severity-the Clinical Global Impression-Schizophrenia scale-were also administered to assess validity.
    RESULTS: Good internal consistency reliability was found for both the psychosocial and vitality domains (Cronbach's α = 0.95 and 0.85, respectively). Most items were also significantly correlated with their own scale score (rs ranging from 0.29 to 0.74). There was a moderate correlation between the SQLS-R4 "vitality" domain and the EuroQol five-dimensional questionnaire "usual activities" domain (rs = 0.44) and a large correlation between the SQLS-R4 "psychosocial" domain and the EuroQol five-dimensional questionnaire "anxiety/depression" domain (rs = 0.44-0.57). Most of the symptom dimensions of the Clinical Global Impression-Schizophrenia scale were also moderately correlated with the SQLS-R4 subscale scores.
    CONCLUSIONS: The SQLS-R4 is a valid and reliable health-related quality-of-life instrument for use in minimally ill patients with schizophrenia in Malaysia, but some of the items may be redundant and irrelevant. Validation of SQLS-R4 in different types of patients and various levels of illness severity is required to further verify its application.
    Study site: Psychiatry clinic, Pusat Perubatan Universiti Kebangsaan Malaysia (PPUKM), Kuala Lumpur, Malaysia
    Matched MeSH terms: Quality of Life*
  18. Mustafa AA, Raad K, Mustafa NS
    Clin Case Rep, 2015 Nov;3(11):907-11.
    PMID: 26576270 DOI: 10.1002/ccr3.373
    Here, we aimed to assess whether postoperative oral rehabilitation for mandibulectomy patients is necessary to improve patients' general health in terms of health-related quality of life.
    Matched MeSH terms: Quality of Life
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