Displaying publications 2061 - 2080 of 2816 in total

Abstract:
Sort:
  1. Fulltext Rural-urban comparisons of dengue seroprevalence in Malaysia
    Chew CH, Woon YL, Amin F, Adnan TH, Abdul Wahab AH, Ahmad ZE, et al.
    BMC Public Health, 2016 08 18;16(1):824.
    PMID: 27538986 DOI: 10.1186/s12889-016-3496-9
    BACKGROUND: Each year an estimated 390 million dengue infections occur worldwide. In Malaysia, dengue is a growing public health concern but estimate of its disease burden remains uncertain. We compared the urban-rural difference of dengue seroprevalence and determined age-specific dengue seroprevalence in Malaysia.

    METHODS: We undertook analysis on 11,821 subjects from six seroprevalence surveys conducted in Malaysia between 2001 and 2013, which composed of five urban and two rural series.

    RESULTS: Prevalence of dengue increased with age in both urban and rural locations in Malaysia, which exceeded 90 % among those aged 70 years or beyond. The age-specific rates of the 5 urban surveys overlapped without clear separation among them, while prevalence was lower in younger subjects in rural series than in urban series, the trend reversed in older subjects. There were no differences in the seroprevalence by gender, ethnicity or region. Poisson regression model confirmed the prevalence have not changed in urban areas since 2001 but in rural areas, there was a significant positive time trend such that by year 2008, rural prevalence was as high as in urban areas.

    CONCLUSION: Dengue seroprevalence has stabilized but persisted at a high level in urban areas since 2001, and is fast stabilizing in rural areas at the same high urban levels by 2008. The cumulative seroprevalence of dengue exceeds 90 % by the age of 70 years, which translates into 16.5 million people or 55 % of the total population in Malaysia, being infected by dengue by 2013.

    Matched MeSH terms: Child, Preschool
  2. Epidemiological Characteristics of Strongyloidiasis in Inhabitants of Indigenous Communities in Borneo Island, Malaysia
    Ngui R, Halim NA, Rajoo Y, Lim YA, Ambu S, Rajoo K, et al.
    Korean J Parasitol, 2016 Oct;54(5):673-678.
    PMID: 27853126
    Epidemiological study on strongyloidiasis in humans is currently lacking in Malaysia. Thus, a cross-sectional study was carried out to determine the prevalence of Strongyloides stercoralis infection among the inhabitants of longhouse indigenous communities in Sarawak. A single stool and blood sample were collected from each participant and subjected to microscopy, serological and molecular techniques. Five species of intestinal parasites were identified by stool microscopy. None of the stool samples were positive for S. stercoralis. However, 11% of 236 serum samples were seropositive for strongyloidiasis. Further confirmation using molecular technique on stool samples of the seropositive individuals successfully amplified 5 samples, suggesting current active infections. The prevalence was significantly higher in adult males and tended to increase with age. S. stercoralis should no longer be neglected in any intestinal parasitic survey. Combination of more than 1 diagnostic technique is necessary to increase the likelihood of estimating the 'true' prevalence of S. stercoralis.
    Matched MeSH terms: Child, Preschool
  3. Duplication 17p11.2 (Potocki-Lupski Syndrome) in a child with developmental delay
    Shuib S, Saaid NN, Zakaria Z, Ismail J, Abdul Latiff Z
    Malays J Pathol, 2017 Apr;39(1):77-81.
    PMID: 28413209 MyJurnal
    Potocki-Lupski syndrome (PTLS), also known as duplication 17p11.2 syndrome, trisomy 17p11.2 or dup(17)(p11.2p11.2) syndrome, is a developmental disorder and a rare contiguous gene syndrome affecting 1 in 20,000 live births. Among the key features of such patients are autism spectrum disorder, learning disabilities, developmental delay, attention-deficit disorder, infantile hypotonia and cardiovascular abnormalities. Previous studies using microarray identified variations in the size and extent of the duplicated region of chromosome 17p11.2. However, there are a few genes which are considered as candidates for PTLS which include RAI1, SREBF1, DRG2, LLGL1, SHMT1 and ZFP179. In this report, we investigated a case of a 3-year-old girl who has developmental delay. Her chromosome analysis showed a normal karyotype (46,XX). Analysis using array CGH (4X44 K, Agilent USA) identified an ~4.2 Mb de novo duplication in chromosome 17p11.2. The result was confirmed by fluorescence in situ hybridization (FISH) using probes in the critical PTLS region. This report demonstrates the importance of microarray and FISH in the diagnosis of PTLS.
    Matched MeSH terms: Child, Preschool
  4. Genetic disorders in Southern Africa
    Beighton P
    S. Afr. Med. J., 1976 Jul 10;50(29):1125-8.
    PMID: 959924
    Certain uncommon genetic disorders occur relatively frequently in the various population groups of Southern Africa. Prominent among these are porphyria, colonic polyposis and sclerosteosis in the Afrikaner community, Huntington's chorea in the British, Gaucher's and Tay-Sachs diseases in the Jewish population, glucose-6-phosphate dehydrogenase deficiency (G-6-PD deficiency) and thalassaemia in the Greek community, various skeletal dysplasias in the Black group, lipoid proteinosis and cleidocranial dysostosis in the Cape Coloured population, diabetes mellitus in the Indian community and retinitis pigmentosa in the Tristan da Cunha islanders. In addition, 'private' syndromes have been encountered in virtually every group. Awareness of the ethnic distribution of unusual genetic conditions is of considerable practical importance during the differential diagnosis of obscure disease.
    Matched MeSH terms: Child, Preschool
  5. Clinical and laboratory presentation of malaria: an analysis of one thousand subjects with malaria parasitaemia
    O'Holohan DR
    J Trop Med Hyg, 1976 Sep;79(9):191-6.
    PMID: 794512
    In the context of this study the ethnic origin of the patients revealed no noteworthy difference in the clinical reaction to the parasite; neither did age or sex of the patients. Any minor differences whcih appeared in length of history before seeking treatment and frequency of repeat attacks were more a reflection of the cultural pattern of response to illness (i.e. resort to traditional medicines) and the distance between the patient's home and the doctor rather than any altered response on the part of the host to the parasite. However, the fact that about 35 per cent of all the episodes had a history of eight or more days (about 10 per cent more than 30 days) suggest that more "malaria consciousness" is called for in what is after all an endemic malaria area. The value (and necessity) of repeated examination of the blood to detect the parasite is confirmed but it is also encouraging to note that in 84% of cases a single careful examination of the blood revealed the parasite. Since in 49% of our malaria episodes the patient was afebrile when the parasite was discovered, it is obvious that in outpatient practice especially blood should be examined when the patient presents for treatment, irrespective of the presence or absence of pyrexia. As always, a prerequisite to the diagnosis of malaria is an awareness of its possible presence.
    Matched MeSH terms: Child, Preschool
  6. Pneumonia and diarrhoeas: killers of toddlers in developing countries
    Chen ST
    Trop Geogr Med, 1975 Mar;27(1):103-8.
    PMID: 806152
    Pneumonia and diarrhoeas are an important cause of toddler mortality and morbidity in developing countries. Of the 147 children admitted to the University Hospital at Kuala Lumpur in 1971 for pneumonia and diarrhoeas 50 (34%) were found to be suffering from protein-calorie malnutrition of varying degrees of severity. The malnourished children tended to come from poorer homes, and to have a larger number of siblings born in rapid succession when compared with normal weight children. Anemia was more common among the malnourished children. The interaction of infection and malnutrition and the social implications of these diseases are important. It is vital that hospitals in developing countries promote health in addition to their traditional curative role.
    Matched MeSH terms: Child, Preschool
  7. A study of immunoglobulin levels among Singapore infants and children
    Paul FM, Leng T, Wee R
    J Singapore Paediatr Soc, 1972 Apr;14(1):1-16.
    PMID: 4626321
    Matched MeSH terms: Child, Preschool
  8. An epidemiological study of cancers in the university hospital: a preliminary report
    Huat LH
    Med J Malaysia, 1979 Sep;34(1):32-7.
    PMID: 542148
    Matched MeSH terms: Child, Preschool
  9. A comparative study of malaria prophylaxis in peninsular Malaysia using chloroquine and a combination of sulphadoxine and pyrimethamine
    Ponnampalam JT
    J Trop Med Hyg, 1978 Oct;81(10):198-203.
    PMID: 366165
    Matched MeSH terms: Child, Preschool
  10. Single dose treatment with Tiberal of Giardia lamblia infection in children
    Iyngkaran N, Lee IL, Robinson MJ
    Scand. J. Infect. Dis., 1978;10(3):243-6.
    PMID: 362519
    A new metronidazole derivative, Tiberal (Ro-07-0207, Roche Laboratories), was evaluated in 22 children with Giardia lamblia infection. Seven patients received an oral dose of 1 g twice daily for one day; the remaining 15 patients received a single dose of 50 mg/kg. Parasitological cure was noted in all 22 patients. Significant side effects were observed only in those children who received the drug at the higher dosage regime. The present study also confirms the findings of other authors that a mucosal imprint method is more reliable than examination of stools, duodenal juice or jejunal biopsy material for the detection of G. lamblia infection.
    Matched MeSH terms: Child, Preschool
  11. Arbovirus infections in Sarawak, October 1968-February 1970: human serological studies in a land Dyak village
    Bowen ET, Simpson DI, Platt GS, Way HJ, Bright WF, Day J, et al.
    Trans R Soc Trop Med Hyg, 1975;69(2):182-6.
    PMID: 809868
    449 human sera collected in a Land Dyak village were tested for antibodies to 11 arboviruses. Japanese encephalitis and dengue virus antibodies were particularly prevalent. The rates of infection with these viruses were estimated to be 5-2% per annum for Japanese encephalitis, 8-8% for dengue 1 and 4-3% for dengue 2. Chikungunya virus antibodies were quite common with an annual infection rate of the order of 5% per annum. Infections with other Group A and B and Bunyamwera group viruses were generally at a low level.
    Matched MeSH terms: Child, Preschool
  12. Attendance at a child health clinic in Malaysia
    Chen PC
    J Trop Med Hyg, 1975 Jan;78(1):6-12.
    PMID: 1121041
    One hundred and ninety-nine children brought by 181 adults to a child health clinic based in a rural health sub-centre in Peninsular Malaysia are studied. It is noted that the families from which they come are relatively poor, with a large number of children, and that they are fairly highly motivated. Forty-four per cent of children attending the clinic at the time of the study are symptomatic indicating the need to organise the child health clinic on a "preventive-curative" basis. It is also noted that the young child is initially seen in early infancy but is lost to the clinic when he is older making it judicious to formulate immunization schedules that take this into account.
    Matched MeSH terms: Child, Preschool
  13. Single-dose and short course regimens of metronidazole in the treatment of amoebiasis in Malaysia
    O'Holohan DR, Hugoe-Matthews J
    Ann Trop Med Parasitol, 1972 Jun;66(2):181-6.
    PMID: 4338870
    Matched MeSH terms: Child, Preschool
  14. Providing maternal and child care in rural Malaysia
    Chen PC
    Trop Geogr Med, 1977 Dec;29(4):441-8.
    PMID: 610030
    Since Independence, gained in 1957, major changes have occurred in the rural areas of Malaysia not least amongst which has been the provision of maternal and child care services to hitherto neglected areas. In the first part of this paper, the demographic and disease patterns are described. The second part outlines the general development efforts and describes in greater detail the rural health services that have been organized in Malaysia. In the concluding section, changes in mortality and morbidity are examined.
    Matched MeSH terms: Child, Preschool
  15. Serum thyrotropin levels of natives in Sarawak, Borneo Island
    Ogihara T, Yamamoto T, Fukuchi M, Oki K
    J Clin Endocrinol Metab, 1972 Nov;35(5):711-5.
    PMID: 5071341
    Matched MeSH terms: Child, Preschool
  16. Review of tuberculosis among the Orang Asli (Aborigines) in West Malaysia from 1951-1970
    Bolton JM, Snelling MR
    Med J Malaysia, 1975 Sep;30(1):10-29.
    PMID: 813093
    Matched MeSH terms: Child, Preschool
  17. Fulltext Incidence of nasopharyngeal carcinoma in Malaysia, with special reference to the state of Selangor
    Armstrong RW, Kutty MK, Dharmalingam SK
    Br. J. Cancer, 1974 Jul;30(1):86-94.
    PMID: 4413823
    A "registry" of all known cases of nasopharyngeal carcinoma in Malaysia, 1968-72, was established. Attention was focused on the State of Selangor where conditions are best for case finding. Age-adjusted incidence rates among Chinese males and females were 17·3 and 7·3 per 100,000; among Malay males and females, the rates were 2·5 and 0·3 and among Indian males, 1·1. The detailed ethnicity of 192 cases in Selangor was established. Estimated incidence rates for the Chinese sub-groups agreed with the pattern observed elsewhere: highest among the Cantonese, lowest among the Hokkien/Teochiu, with the Khek in between. There was no correlation between histological type and sub-ethnic group among the Chinese cases.
    Matched MeSH terms: Child, Preschool
  18. Studies of bacterial disease in West Malaysian Orang Asli. Distribution of enteropathogens
    Haug NL, Davis CE, Anandan J, Lim TW
    Med J Malaya, 1969 Sep;24(1):24-31.
    PMID: 4243839
    Matched MeSH terms: Child, Preschool
  19. An International Working Conference on Nutrition and Infection
    Gordon JE, Scrimsha NS
    Arch. Environ. Health, 1969 Aug;19(2):199-216.
    PMID: 5817545
    Matched MeSH terms: Child, Preschool
  20. Assessing primary care data quality
    Lim YMF, Yusof M, Sivasampu S
    Int J Health Care Qual Assur, 2018 Apr 16;31(3):203-213.
    PMID: 29687760 DOI: 10.1108/IJHCQA-08-2016-0111
    Purpose The purpose of this paper is to assess National Medical Care Survey data quality. Design/methodology/approach Data completeness and representativeness were computed for all observations while other data quality measures were assessed using a 10 per cent sample from the National Medical Care Survey database; i.e., 12,569 primary care records from 189 public and private practices were included in the analysis. Findings Data field completion ranged from 69 to 100 per cent. Error rates for data transfer from paper to web-based application varied between 0.5 and 6.1 per cent. Error rates arising from diagnosis and clinical process coding were higher than medication coding. Data fields that involved free text entry were more prone to errors than those involving selection from menus. The authors found that completeness, accuracy, coding reliability and representativeness were generally good, while data timeliness needs to be improved. Research limitations/implications Only data entered into a web-based application were examined. Data omissions and errors in the original questionnaires were not covered. Practical implications Results from this study provided informative and practicable approaches to improve primary health care data completeness and accuracy especially in developing nations where resources are limited. Originality/value Primary care data quality studies in developing nations are limited. Understanding errors and missing data enables researchers and health service administrators to prevent quality-related problems in primary care data.
    Matched MeSH terms: Child, Preschool
Related Terms
Filters
Contact Us

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links