MyMedR

Fulltext HDG-select: A novel GUI based application for gene selection and classification in high dimensional datasets

Hameed SS, Hassan R, Hassan WH, Muhammadsharif FF, Latiff LA

PLoS One, 2021;16(1):e0246039.

PMID: 33507983 DOI: 10.1371/journal.pone.0246039

The selection and classification of genes is essential for the identification of related genes to a specific disease. Developing a user-friendly application with combined statistical rigor and machine learning functionality to help the biomedical researchers and end users is of great importance. In this work, a novel stand-alone application, which is based on graphical user interface (GUI), is developed to perform the full functionality of gene selection and classification in high dimensional datasets. The so-called HDG-select application is validated on eleven high dimensional datasets of the format CSV and GEO soft. The proposed tool uses the efficient algorithm of combined filter-GBPSO-SVM and it was made freely available to users. It was found that the proposed HDG-select outperformed other tools reported in literature and presented a competitive performance, accessibility, and functionality.

Fulltext IoMT amid COVID-19 pandemic: Application, architecture, technology, and security

Mohd Aman AH, Hassan WH, Sameen S, Attarbashi ZS, Alizadeh M, Latiff LA

J Netw Comput Appl, 2021 Jan 15;174:102886.

PMID: 34173428 DOI: 10.1016/j.jnca.2020.102886

In many countries, the Internet of Medical Things (IoMT) has been deployed in tandem with other strategies to curb the spread of COVID-19, improve the safety of front-line personnel, increase efficacy by lessening the severity of the disease on human lives, and decrease mortality rates. Significant inroads have been achieved in terms of applications and technology, as well as security which have also been magnified through the rapid and widespread adoption of IoMT across the globe. A number of on-going researches show the adoption of secure IoMT applications is possible by incorporating security measures with the technology. Furthermore, the development of new IoMT technologies merge with Artificial Intelligence, Big Data and Blockchain offers more viable solutions. Hence, this paper highlights the IoMT architecture, applications, technologies, and security developments that have been made with respect to IoMT in combating COVID-19. Additionally, this paper provides useful insights into specific IoMT architecture models, emerging IoMT applications, IoMT security measurements, and technology direction that apply to many IoMT systems within the medical environment to combat COVID-19.

Fulltext Pandemic influenza A (H1N1) and its prevention: a cross sectional study on patients' knowledge, attitude and practice among patients attending primary health care clinic in Kuala Lumpur, Malaysia

Latiff LA, Parhizkar S, Zainuddin H, Chun GM, Rahiman MA, Ramli NL, et al.

Glob J Health Sci, 2012 Feb 29;4(2):95-102.

PMID: 22980156 DOI: 10.5539/gjhs.v4n2p95

The World Health Organization confirmed that the novel influenza A, H1N1 as a pandemic on 11 June 2009. After less than three months, 182 countries were affected by the pandemic accounting for about 150,000 infected cases and 3000 mortality. Successful H1N1 pandemic management strategies' shaped by making changes in health behavior. The aim of this study was to document patients' knowledge, attitudes and practices (KAP) regarding the pandemic influenza A (H1N1) and its prevention. We performed a cross-sectional study on knowledge, attitudes and practices (KAP) on preventive measures of Influenza A (H1N1) involving 322 patients attending Klinik Kesihatan Jinjang, a primary health care clinic in Kuala Lumpur, Malaysia from May 10 to 26, 2010 using a face to face interview with a structured pre-tested questionnaire. The majority of the respondents were females (56.8%), Malays (43.2%) aged between 18-27 years old (28.9%). There were significant association between knowledge on the complication of H1N1, effectiveness of the treatment, preventive measures of Influenza A (H1N1) and race (p<0.001) and educational level (p<0.001). There were also significant associations between attitude scores of these patients and their gender (p=0.03), and educational level (p=0.001). Practice scores related to H1N1 were found to be significantly associated with race (p<0.001) and educational level (p<0.001). The significant associations were observed between knowledge and attitude (p<0.001), knowledge and practices (p<0.001), as well as attitude and practices related to H1N1 (p<0.001). Knowledge has a crucial effect on patients' attitude and practice particularly in a pandemic spread. So health policy makers should attempt to disseminate information about preventive measures to community in order to improve their preventive practices during pandemics.

Breast cancer prevention information seeking behavior and interest on cell phone and text use: a cross-sectional study in Malaysia

Akhtari-Zavare M, Ghanbari-Baghestan A, Latiff LA, Khaniki H

Asian Pac J Cancer Prev, 2015;16(4):1337-41.

PMID: 25743795

BACKGROUND: Breast cancer is the most common cancer and the second principal cause of cancer deaths among women worldwide, including Malaysia. This study focused on media choice and attempted to determine the communication channels mostly used and preferred by women in seeking information and knowledge about breast cancer.

MATERIALS AND METHODS: A cross sectional study was carried out to examine the breast cancer prevention information seeking behavior among 450 students at one private university in Malaysia.

RESULTS: The mean age of respondents was 25±4.3 years. Common interpersonal information sources were doctors, friends, and nurses and common channel information sources were television, brochure, and internet. Overall, 89.9% used cell phones, 46.1% had an interest in receiving cell phone breast cancer prevention messages, 73.9% used text messaging, and 36.7% had an interest in receiving text breast cancer prevention messages. Bivariate analysis revealed significant differences among age, eduation, nationality and use of cell phones.

CONCLUSIONS: Assessment of health information seeking behavior is important for community health educators to target populations for program development.

Comparison of gait parameters across three attentional loading conditions during timed up and go test in stroke survivors

Manaf H, Justine M, Ting GH, Latiff LA

Top Stroke Rehabil, 2014 Mar-Apr;21(2):128-36.

PMID: 24710973 DOI: 10.1310/tsr2102-128

Little is known about the effects of attentional loading on performance of turning during walking in individuals with stroke.

Fulltext Toxicity effect of nigella sativa on the liver function of rats

Dollah MA, Parhizkar S, Latiff LA, Bin Hassan MH

Adv Pharm Bull, 2013;3(1):97-102.

PMID: 24312819 DOI: 10.5681/apb.2013.016

The aim of this study was to determine the toxic effect of Nigella sativa powder on the liver function which was evaluated by measuring liver enzymes and through histopathological examination of liver tissue.

Alternative supplement for enhancement of reproductive health and metabolic profile among perimenopausal women: a novel role of Nigella sativa

Latiff LA, Parhizkar S, Dollah MA, Hassan ST

Iran J Basic Med Sci, 2014 Dec;17(12):980-5.

PMID: 25859301

The aim of this open label crossover study was to investigate the effects of Nigella sativa on reproductive health and metabolic profile of perimenopausal women in Rawang, Malaysia.

Emotional health and coping mechanisms among adolescents in Malaysian residential foster care homes: A comparative study with adolescents living with families

Mohammadzadeh M, Tajik E, Awang H, Latiff LA

Asian J Psychiatr, 2018 Feb;32:156-158.

PMID: 29278817 DOI: 10.1016/j.ajp.2017.12.011

Fulltext Contraceptive use among women with chronic medical conditions and factors associated with its non-use in Malaysia

Manaf RA, Ismail IZ, Latiff LA

Glob J Health Sci, 2012 Sep;4(5):91-9.

PMID: 22980381 DOI: 10.5539/gjhs.v4n5p91

INTRODUCTION: Women with chronic medical conditions are at higher risk of adverse pregnancy outcomes, which may be minimized through optimal preconception care and appropriate contraceptive use. This study aimed to describe contraceptive use among women with chronic medical conditions and factors associated with its non-use.
METHODS: This study used cross-sectional data from a family planning survey among women with chronic medical conditions conducted in three health facilities in a southern state of Malaysia. A total of 450 married women in reproductive age (18-50 year) with intact uterus, and do not plan to conceive were analysed for contraceptive use. Both univariate and multivariate analysis was conducted to identify factors associated with contraceptive non-use among the study participants.
RESULTS: A total of 312 (69.3%) of the study participants did not use contraceptive. Contraceptive non-use was highest among the diabetics (71.2%), connective tissue disease patients (68.6%) and hypertensive patients (65.3%). Only 26.3% of women with heart disease did not use contraceptive. In the multivariate analysis, contraceptive non-use was significantly more common among women who received their medical treatment in the health clinics as compared to those who received treatment in the hospital (adjusted odds ratio [OR]=1.75, 95% confidence interval [CI]: 1.09, 2.79), being in older age group of 41-50 year (adjusted OR=2.31, 95% CI: 1.19, 4.48), having children (adjusted OR=4.57, 95% CI: 1.66, 12.57) and having lower education (adjusted OR=2.87, 95% CI: 1.43, 5.77).
CONCLUSION: About two-third of women with chronic medical conditions who needed contraceptive did not use them despite the higher risk of pregnancy related complications. The high unmet need warrant an effective health promotion programme to encourage the uptake of contraceptives especially targeting women of older age group, low education and those who received their medical treatment at health clinics.
Study site: Outpatient clinic, three hospitals; 8 health clinics, Malaysia

Fulltext Effect of Nigella sativa on reproductive system in experimental menopause rat model

Parhizkar S, Latiff LA, Parsa A

Avicenna J Phytomed, 2016 Jan-Feb;6(1):95-103.

PMID: 27247926

Menopause is the condition when regular menstrual periods cease and may be accompanied by psychological and physical symptoms. The purpose of current study was to determine Nigella sativa effects on reproductive system in experimental menopause animal models.

Fulltext Insufficient Knowledge of Breast Cancer Risk Factors Among Malaysian Female University Students

Abu Samah A, Ahmadian M, Latiff LA

Glob J Health Sci, 2016;8(1):277-85.

PMID: 26234996 DOI: 10.5539/gjhs.v8n1p277

Despite continuous argument about the efficacy of breast self-examination; it still could be a life-saving technique through inspiring and empowering women to take better control over their body/breast and health. This study investigated Malaysian female university students' knowledge about breast cancer risk factors, signs, and symptoms and assessed breast self-examination frequency among students.

Electrical Impedance Tomography as a Primary Screening Technique for Breast Cancer Detection

Akhtari-Zavare M, Latiff LA

Asian Pac J Cancer Prev, 2015;16(14):5595-7.

PMID: 26320422

Electrical impedance tomography (EIT) is a new non-invasive, mobile screening method which does not use ionizing radiation to the human breast. It is based on the theory that cancer cells display altered local dielectric properties, thus demonstrating measurably higher conductivity values. This article reviews the utilisation of EIT in breast cancer detection. It could be used as an adjunct to mammography and ultrasonography for breast cancer screening.

Displaying publications 21 - 32 of 32 in total