Displaying publications 41 - 60 of 2346 in total

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  1. Tan SB, Chee CH, Ngai CF, Hii SL, Tan YW, Ng CG, et al.
    BMJ Support Palliat Care, 2024 Jan 08;13(e3):e1117-e1125.
    PMID: 35459688 DOI: 10.1136/bmjspcare-2021-003349
    OBJECTIVES: Suffering is common among patients with advanced cancer. The practice of mindfulness during patient care can potentially reduce suffering. We aimed to examine the efficacy of mindfulness-based supportive therapy (MBST) on reducing suffering in patients with advanced cancer.

    METHODS: We conducted a parallel-group, single-blinded, randomised controlled trial at the University of Malaya Medical Centre, Malaysia. Seventy-three patients with advanced cancer with an overall suffering score ≥4/10 based on the Suffering Pictogram were recruited and randomly assigned into either the MBST group (n=34) or the control group (n=39).

    RESULTS: There was a statistically significant reduction in the overall suffering score in the MBST group compared with the control group (U=432.5, median1=-2.0, median2=-1.0, z=-2.645, p=0.008). There was also significant improvement in the total Hospital Anxiety and Depression Scale score (U=483.5, median1=-4.0, median2=-3.0, z=-1.994, p=0.046), and the total Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being score (U=252.0, median1=+14.5, median2=+5.0, z=-4.549, p=0.000) in the MBST group compared with the control group.

    CONCLUSIONS: The results provided evidence that the practice of MBST during patient care could promote positive psychosocial outcomes.

    Matched MeSH terms: Quality of Life
  2. Cheah YK
    Malays J Med Sci, 2013 Jan;20(1):46-55.
    PMID: 23613658 MyJurnal
    In light of the fact that chronic diseases were becoming more prevalent recently, the primary objective of the study was to examine the socio-demographic, health, and lifestyle determinants of the use of preventive medical care in Penang, Malaysia.
    Matched MeSH terms: Life Style
  3. Whitcroft KL, Altundag A, Balungwe P, Boscolo-Rizzo P, Douglas R, Enecilla MLB, et al.
    Rhinology, 2023 Oct 01;61(33):1-108.
    PMID: 37454287 DOI: 10.4193/Rhin22.483
    BACKGROUND: Since publication of the original Position Paper on Olfactory Dysfunction in 2017 (PPOD-17), the personal and societal burden of olfactory disorders has come sharply into focus through the lens of the COVID-19 pandemic. Clinicians, scientists and the public are now more aware of the importance of olfaction, and the impact of its dysfunction on quality of life, nutrition, social relationships and mental health. Accordingly, new basic, translational and clinical research has resulted in significant progress since the PPOD-17. In this updated document, we present and discuss currently available evidence for the diagnosis and management of olfactory dysfunction. Major updates to the current version include, amongst others: new recommendations on olfactory related terminology; new imaging recommendations; new sections on qualitative OD and COVID-19 OD; updated management section. Recommendations were agreed by all co-authors using a modified Delphi process.

    CONCLUSIONS: We have provided an overview of current evidence and expert-agreed recommendations for the definition, investigation, and management of OD. As for our original Position Paper, we hope that this updated document will encourage clinicians and researchers to adopt a common language, and in so doing, increase the methodological quality, consistency, and generalisability of work in this field.

    Matched MeSH terms: Quality of Life
  4. Wong YJ, Noordin NM, Keshavjee S, Lee SWH
    Eur Respir Rev, 2021 Mar 31;30(159).
    PMID: 33408089 DOI: 10.1183/16000617.0260-2020
    The impact of latent tuberculosis infection (LTBI) on health and wellbeing is not well understood. This review aims to evaluate the health and wellbeing of individuals with LTBI. A systematic literature search was performed to assess studies reporting patient-reported outcomes in LTBI management including health-related quality of life (HRQoL), health utilities, disease burden and experience of individuals with LTBI. A pooled analysis was performed to estimate the effect of LTBI on HRQoL.A total of 4464 studies were screened, of which 13 eligible articles describing nine unique studies were included for review. The HRQoL of individuals with LTBI and without tuberculosis (TB) infection were comparable, and better than patients with active TB disease. However, individuals with LTBI reported poorer mental health compared with individuals without TB infection (mean difference -4.16, 95% CI -7.45- -0.87; p=0.01). Qualitative studies suggest the presence of fear, anxiety and stigma in individuals with LTBI.This review highlights potential psychosocial challenges in individuals with LTBI despite the absence of clinical symptoms. While their quality of life was marginally affected, this could be evidence to support LTBI management in preventing TB re-activation and the severe consequences of active TB disease that affect all domains of HRQoL.
    Matched MeSH terms: Quality of Life
  5. Syed IA, Syed Sulaiman SA, Hassali MA, Lee CK
    Health Expect, 2015 Oct;18(5):1363-70.
    PMID: 24010818 DOI: 10.1111/hex.12116
    BACKGROUND: Health-related quality of life (HRQoL) is increasingly recognized as an important outcome and as a complement to traditional biological end points of diseases such as mortality. Unless there is a complete cure available for HIV/AIDS, development and implementation of a reliable and valid cross cultural quality of life measure is necessary to assess not only the physical and medical needs of HIV/AIDS people, but their psychological, social, environmental, and spiritual areas of life.
    METHODS: A qualitative exploration of HIV/AIDS patients' understanding, perceptions and expectations will be carried out with the help of semi structured interview guide by in depth interviews, while quantitative assessment of patient reported adverse drug reactions and their impact on health related quality of life will be carried out by using data collection tool comprising patient demographics, SF-12, Naranjo scale, and a clinical data sheet.
    RESULTS/OUTCOMES: The findings may serve as baseline QOL data of people living with HIV/AIDS in Malaysia and also a source data to aid construction of management plan to improve HIV/AIDS patients' QOL. It will also provide basic information about HIV/AIDS patients' perceptions, expectations and believes towards HIV/AIDS and its treatment which may help in designing strategies to enhance patients' awareness which in turn can help in addressing issues related to compliance and adherence.
    KEYWORDS: HIV/AIDS; adverse drug reactions; patients' perspective; quality of life
    Matched MeSH terms: Quality of Life*
  6. Ezat WP, Noraziani K, Sabrizan O
    Asian Pac J Cancer Prev, 2012;13(3):1069-75.
    PMID: 22631640
    There are an almost infinite number of states of health, all with differing qualities that can be affected by many factors. Each aspect of health has many components which contribute to multidimensionality. Cancer and its' related issues surrounding the treatment plan contribute to the variety of changes of quality of life of cancer patients throughout their life. The objective of this article was to provide an overview of some of the issues that can affect their quality of life and initiatives towards successful care in Malaysia by reviewing relevant reports and articles. The current strategies can be further strengthened by prevention of cancer while improving quality of service to cancer patients.
    Matched MeSH terms: Quality of Life*
  7. Sing KW, Dong H, Wang WZ, Wilson JJ
    Genome, 2016 Sep;59(9):751-61.
    PMID: 27314400 DOI: 10.1139/gen-2015-0192
    During 30 years of unprecedented urbanization, plant diversity in Shenzhen, a young megacity in southern China, has increased dramatically. Although strongly associated with plant diversity, butterfly diversity generally declines with urbanization, but this has not been investigated in Shenzhen. Considering the speed of urbanization in Shenzhen and the large number of city parks, we investigated butterfly diversity in Shenzhen parks. We measured butterfly species richness in four microhabitats (groves, hedges, flowerbeds, and unmanaged areas) across 10 parks and examined the relationship with three park variables: park age, park size, and distance from the central business district. Butterflies were identified based on wing morphology and DNA barcoding. We collected 1933 butterflies belonging to 74 species from six families; 20% of the species were considered rare. Butterfly species richness showed weak negative correlations with park age and distance from the central business district, but the positive correlation with park size was statistically significant (p = 0.001). Among microhabitat types, highest species richness was recorded in unmanaged areas. Our findings are consistent with others in suggesting that to promote urban butterfly diversity it is necessary to make parks as large as possible and to set aside areas for limited management. In comparison to neighbouring cities, Shenzhen parks have high butterfly diversity.
    Matched MeSH terms: Life Style*
  8. Lee THB, Sundar G
    Ophthalmic Plast Reconstr Surg, 2019 10 1;36(2):118-126.
    PMID: 31567783 DOI: 10.1097/IOP.0000000000001446
    PURPOSE: The aim of this systematic review is to provide 1) an understanding of the components of quality of life (QOL) questionnaires and 2) an up-to-date insight of the types of QOL questionnaires available, strengths and limitations based on current literature.

    METHODS: A literature search was conducted from 18 to 21 of February 2019 using 6 major databases: Cochrane Library, Ovid Medline, PubMed, Scopus, Taylor and Francis, and Web of Science. All papers were skimmed by title and abstract to determine whether the paper fulfilled the screening criteria. In cases of uncertainty, the paper was read in totality to justify its inclusion. After that, duplicates were eliminated and the remainder was subjected to a second set of inclusion and exclusion criteria before finalizing the list of included studies.

    RESULTS: An initial search returned with 402 studies, which were subsequently filtered using prespecified criteria to 27 studies to collate information regarding questionnaires assessing QOL of thyroid eye disease patients.

    CONCLUSIONS: The QOL of thyroid eye disease patients is best assessed using disease-specific questionnaires. Among the different types of questionnaires, the Graves Ophthalmopathy Quality of Life (GO-QOL) questionnaire is preferred due to its' ability to explore QOL in-depth and proven efficacy in many countries after cultural adaptation at the expense of time. Single-item questionnaires like the Thyroid Eye Disease Quality of Life (TED-QOL) are more suitable as screening tools in busy metropolitan settings while semi-structured interviews are important in developing new ways of assessing the QOL of thyroid eye disease patients.

    Matched MeSH terms: Quality of Life*
  9. Efficace F, Iurlo A, Patriarca A, Stagno F, Bee PC, Ector G, et al.
    Leuk Lymphoma, 2021 03;62(3):669-678.
    PMID: 33153355 DOI: 10.1080/10428194.2020.1838509
    Health-related quality of life (HRQOL) assessment is important to facilitate decisions in the current treatment landscape of chronic myeloid leukemia (CML). Therefore, the availability of a validated HRQOL questionnaire, specifically developed for CML patients treated with tyrosine kinase inhibitors (TKIs), may enhance quality of research in this area. We performed an international study including 782 CML patients to assess the validity of the EORTC QLQ-CML 24 questionnaire, and to generate HRQOL reference values to facilitate interpretation of results in future studies. Internal consistency, assessed with Cronbach's alpha coefficients, ranged from 0.66 to 0.83. In the confirmatory factor analysis, all standardized factor loadings exceeded the threshold of 0.40 (range 0.49-0.97), confirming the hypothesized scale structure. Reference values stratified by age and sex were also generated. Our findings support the use of the EORTC QLQ-CML 24, in conjunction with the EORTC QLQ-C30, as a valuable measure to assess HRQOL in CML patients.
    Matched MeSH terms: Quality of Life*
  10. Mustafa NWNA, Ishak NH, Mohd Rosli NA, Nik Zulkifeli NR, Rajali A
    Complement Ther Clin Pract, 2021 May;43:101392.
    PMID: 33862351 DOI: 10.1016/j.ctcp.2021.101392
    BACKGROUND: Gagging condition is among factors contributing to avoidance behavior to seek the dental treatment, and rigorous management is still under investigation. This study aims to explore the effect of listening to the self-preference music in reducing the gagging condition during dental impression procedure towards gagging patient. Physiology and psychological impact to the procedure with and without musical intervention are investigated.

    METHOD AND MATERIAL: A group of twenty-five patients that will undergo impression procedure was randomly selected. Self-reported Gagging Problem Assessment (GPA-pa-SF) questionnaires was then administered to determine the severity of gagging. Maxillary impression was taken twice within the same patient in two different time intervals (1st without any intervention and 2nd with musical intervention). During both procedures, the pulse rate/minutes (BPM) and arterial oxygen saturation of haemoglobin (SpO2%) were recorded and psychometric assessment was evaluated through the Oral Health Impact Profile (OHIP-14).

    RESULT: Mean value of BPM was significantly reduced with music (p 

    Matched MeSH terms: Quality of Life*
  11. Rosli MR, Wu DB, Neoh CF, Karuppannan M
    J Med Econ, 2021 5 15;24(1):730-740.
    PMID: 33989086 DOI: 10.1080/13696998.2021.1889573
    OBJECTIVE: Home medication review (HMR) programs could minimise patients' health-related costs and burdens, thereby enhancing the quality of life and well-being. The aim of this economic evaluation is to determine if home medication review by community pharmacists (HMR-CP) for patients with type 2 diabetes mellitus (T2DM) is a cost-effective intervention from the Malaysian healthcare provider perspective.

    METHODS: The economic evaluation was conducted alongside the randomised controlled trial (RCT) to estimate the intermediate cost-effectiveness of HMR-CP for patients with T2DM. A Markov model was then constructed to project the lifetime cost-effectiveness data beyond the RCT. The primary outcomes for the economic evaluation were HbA1c and quality-adjusted life-years (QALYs).

    RESULTS: The intervention and health services costs throughout the 6-month HMR-CP trial were RM121.45 (USD28.64) [95%CI: RM115.89 to 127.08 (USD27.33-29.97)] per participant. At a 6-month follow-up, a significant reduction in HbA1c of 0.902% (95% CI: 0.388% to 1.412%) was noted in the HMR-CP group compared to the control group. The ICER of HMR-CP intervention versus standard care was RM178.82 (USD 42.17) [95%CI: RM86.77-364.03 (USD20.46-85.86)] per reduction of HbA1c. HMR-CP intervention [RM12,764.82 (USD3010.57)] was associated with an incremental cost of RM83.34 (USD19.66) over control group [RM12,682.95 (USD2,991.26)] with an additional of 0.07 QALY gained. The ICER associated with HMR-CP intervention was RM1,190.57 (USD280.79) per QALY gained, which was below the ICER threshold in Malaysia, indicating that HMR-CP was a cost-effective option.

    CONCLUSION: HMR-CP was a cost-effective intervention that had significantly reduced the HbA1c among the T2DM patients, although associated with higher mean total costs per participant.

    Matched MeSH terms: Quality of Life; Quality-Adjusted Life Years
  12. DAVIES TA, MILLS R
    Med J Malaya, 1956 Sep;11(1):1-19.
    PMID: 13399539
    Matched MeSH terms: Life*
  13. Raihana, Z., Farah Nabilah, A.M.
    MyJurnal
    Most studies done in the past on factors affecting academic performance did not touch on quality of life factor. Also, most studies only used correlation and regression analysis. Not many studies used classification analysis. Hence, this study aimed to classify students based on quality of life and academic performance. Students’ quality of life was measured by using WHOQOL-BREF questionnaire which consists of five quality of life domains namely physical health, psychological health, social relationship, environment and overall quality of life whereas the academic performances were represented by cumulative grade point average (CGPA). The selected sample for this study was 60 Universiti Teknologi MARA (UiTM) Perlis students from Bachelor of Science (Hons.) Management Mathematics program. This study applied support vector machine (SVM) method for classifying the students. The results for each quality of life domain showed that students with both low and high academic performance were classified into high academic performance class. The same result was obtained when all domains were combined. All models showed high accuracy which implied that the classification made by SVM were strongly correct. The findings of this study demonstrated that quality of life plays an important role in students’ academic performance.
    Matched MeSH terms: Quality of Life*
  14. Farah Shazlin Johari, Muhammad Ridzuan Ruslani, Nor Maslia Rasli Samudin, Nurhafizah Mohd Zolkapli, Siti Norashikin Basirun
    MyJurnal
    Work-life balance play an important role in influencing employee’s quality of social and working life together with job satisfaction in the organization. Nowadays, teachers are also included in the context of work-life balance due to academic workload and career issues. In
    this study, researchers aim to explore work-life balance policies that influence teacher’s job satisfaction in selected Malaysia boarding school. Only 56 school teachers were selected to represent as respondents consist of teachers from language, mathematics, science, social science, counselling unit, and vice principals department. The questionnaires were distributed using convenience sampling. The elements of work-life balance policies such as flexibility policies, welfare policies, job design and leave provisions were included in this study to examine potential influence on teacher’s job satisfaction. Based on statistical analysis using SPSS, Pearson Correlation analysis four elements of work-life balance policies indicated positive and significant relationship with job satisfaction, with flexibility policies showed the strongest relationship toward teacher’s job satisfaction. Most of teachers in selected Malaysian boarding school also demonstrated high level of job satisfaction at the workplace.
    Matched MeSH terms: Work-Life Balance*
  15. Arifah Bahar, Siti Rohani Mohd Nor, Fadhilah Yusof
    Sains Malaysiana, 2018;47:1337-1347.
    The growing number of multi-population mortality models in the recent years signifies the mortality improvement in
    developed countries. In this case, there exists a narrowing gap of sex-differential in life expectancy between populations;
    hence multi-population mortality models are designed to assimilate the correlation between populations. The present
    study considers two extensions of the single-population Lee-Carter model, namely the independent model and augmented
    common factor model. The independent model incorporates the information between male and female separately
    whereas the augmented common factor model incorporates the information between male and female simultaneously.
    The methods are demonstrated in two perspectives: First is by applying them to Malaysian mortality data and second
    is by comparing the significance of the methods to the annuity pricing. The performances of the two methods are then
    compared in which has been found that the augmented common factor model is more superior in terms of historical fit,
    forecast performance, and annuity pricing.
    Matched MeSH terms: Life Expectancy; Life Tables
  16. Safaril, Maadon, Zaiton, Hassan, Mark, Kasa, Ida Juliana, Hutasuhut
    MyJurnal
    Work-Life balance (WLB) studies have investigated heavily on family domain even though
    there are sub domains in life. Thus, this study will contribute to the literature by examining
    study domain (lifelong learning and organizational learning) and its influence on familywork
    enrichment (FWE) among teachers who are currently continuing their education in
    Lundu district. A total of 117 teachers responded to the self-administered questionnaire. The
    finding revealed that both organizational learning and lifelong learning have a positive significant
    relationship with family work enrichment. Therefore, school management should
    encourage the culture of lifelong learning and at the same time provide facilities and atmosphere
    to support the culture will ensure family-work enrichment among teachers who are
    continuing their study.
    Matched MeSH terms: Life; Work-Life Balance
  17. Wong K, Chan AHS, Teh PL
    PMID: 32575807 DOI: 10.3390/ijerph17124446
    The impacts of the work-life balance arrangement on organisational performance is a growing concern amongst researchers and practitioners. This study synthesised 202 records from 58 published papers to evaluate the relationship between the work-life balance arrangement and organisational performance by means of a meta-analysis. The organisational performance was measured based on six perspectives, including career motivation, employee attendance, employee recruitment, employee retention, organisational commitment, and productivity. The results showed a positive relationship between the work-life balance arrangement and organisational performance (OR: 1.181, 95% CI: 1.125-1.240, p < 0.001). Of the six perspectives, only career motivation, employee attendance, employee recruitment, and employee retention were significantly associated with the work-life balance arrangement. The moderators affecting the relationship between the work-life balance arrangement and organisational performance were gender, sector, and employee hierarchy. The results provide theoretical suggestions on the effectiveness of the work-life balance arrangement in terms of the six perspectives related to organisational performance.
    Matched MeSH terms: Work-Life Balance*
  18. Lim R, Liong ML, Leong WS, Lau YK, Khan NAK, Yuen KH
    Urology, 2018 Feb;112:38-45.
    PMID: 29107131 DOI: 10.1016/j.urology.2017.10.019
    OBJECTIVE: To assess the impact of stress urinary incontinence (SUI) on individual components of quality of life (QoL) using both condition-specific and generic questionnaires, and to compare the results of the 2 instruments with a control group.

    METHODS: Women with or without SUI aged ≥21 years old were recruited. Subjects completed the International Consultation of Incontinence-Urinary Incontinence Short Form (ICIQ-UI-SF), International Consultation of Incontinence-Lower Urinary Tract Symptoms Quality of Life (ICIQ-LUTSqol), and EQ-5D questionnaires.

    RESULTS: A total of 120 women with SUI and 145 controls participated. The ICIQ-LUTSqol total score (mean ± standard deviation) was significantly higher in the SUI group (38.96 ± 10.28) compared with the control group (20.78 ± 2.73) (P 

    Matched MeSH terms: Quality of Life*
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