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  1. Shih Sheng Soo, Siti Balkis Budin, Ismarulyusda Ishak, Faridah Mohd Nor, Nur Najmi Mohamad Anuar
    MyJurnal
    Background: Sudden death (SD) is defined as an unexpected natural death within an hour onset of symptoms or unwitnessed death that occurs within 24 hours, which accounts for most cardiovascular deaths in Malaysia. This study aimed to evaluate the extent of histopathological changes in the heart and to study the demographic trend in SD cases in Kuala Lumpur, Malaysia. Methods: Specimens from all SD cases were received from 2017 to 2018 by the Forensic Unit, Hospital Canselor Tuanku Mukhriz (HCTM) were studied. The specimens were the left ventricular myocardium and left anterior descending artery (LAD), which were fixed in 10% formalin with haematoxylin and eosin staining. The tissues were graded histologically based on changes such as arterial occlusion, myocardial infarction, and/or thrombus formation. Results: Out of 545 medicolegal deaths, only 25 cases (4.6%) had samples available for analysis. Among these 25 patients, 24 (96%) were male patients and only one (4%) was a female patient. The available samples were from patients aged between 30 to 79 years old. In terms of ethinicity, Malays (40%) were the most numerous, followed by patients of Chinese and Indian ethnicities.The majority of the SD cases had a body mass index (BMI) that ranged between underweight (56%) and obese (40%). Besides, there were 10 (40%) cases of coronary artery with atheroma and 15 (60%) cases of myocardial infarction. The most common presentation of atherosclerosis was grade III and IV, and acute MI was the most common presentation at death, followed by healed infarcts and old infarcts. Discussion and Conclusion: Our findings reflect worsening risk factor levels in cardiovascular diseases, compounded by demographic trends. Further studies on biomarkers specific for cardiac diseases are warranted to understand imminent sudden cardiac death.
  2. Heo, Chong Chin, Mohamad Abdullah Marwi, Jeffery, John, Ismarulyusda Ishak, Baharudin Omar
    MyJurnal
    This study was carried out in Agricultural Park, Teluk Cempedak and Bukit Pelindung at Kuantan, Pahang in October 2007. These three areas were different in ecological characteristic, Agricultural Park is a lowland region in Kuantan rural area, Teluk Cempedak is Kuantan’s most famous beach, and Bukit Pelindung is a reserved rainforest which is 200 meters from the sea level. Fly specimens were collected using four different kinds of baits: dry prawn, salted fish, pork and mango. Each of these baits was placed in a plastic container and exposed for one hour to attract flies. Within 5 minutes, flies started swarming around the baits. The flies were more attracted to the pork and salted fish compared to the other two baits. Fifty one flies, one moth (Lepidoptera) and one wasp (Hymenoptera) were collected. In Agricultural Park, two Lucilia cuprina, one Chrysomya megacephala and one Sarcophaga sp. were collected. For Teluk Cempedak beach, there were two Sarcophagids, 31 Chrysomya megacephala, five Musca domestica, one Lucilia cuprina and one moth were caught. Flies collected from Bukit Pelindung included five C.megacephala, two Sarcophagids, one Musca domestica and one wasp. Most C.megacephala were attracted to the pork and salted fish.
  3. Ismarulyusda Ishak, Jamaludin Mohamed, Zaleha Md Isa, Zakiah Ismail, Mohd Fairulnizal, Osman Ali, et al.
    Selenium memainkan peranan penting dalam mengekalkan status kesihatan manusia. Pengambilan selenium yang tidak mencukupi boleh menjadi penyebab kepada kejadian penyakit. Satu kajian hirisan lintang telah dijalankan untuk menilai paras selenium serum dalam kalangan populasi di Daerah Hulu Langat, Selangor, Malaysia. Seterusnya taburan menurut faktor sosiodemografi dikenal pasti. Populasi di Daerah Hulu Langat dipilih secara persampelan rawak yang melibatkan enam mukim iaitu Ulu Langat, Ampang, Kajang, Cheras, Beranang dan Semenyih. Seramai 415 orang subjek berumur antara 5-64 tahun telah mengambil bahagian dalam kajian ini. Sampel darah diambil untuk melihat paras selenium dalam serum. Hasil mendapati paras selenium keseluruhan subjek ialah 1.67 + 0.44 μmol/l. Hasil ujian ANOVA dua hala mendapati tiada perbezaan paras selenium yang bererti menurut jantina dengan nilai p=0.981 (p>0.05). Manakala terdapat perbezaan paras selenium yang bererti menurut kumpulan umur dengan nilai p<0.001. Kesan interaksi jantina dan kumpulan umur pula menunjukkan tiada interaksi yang bererti antara kedua faktor tersebut dengan p=0.362 (p>0.05). Perbezaan paras selenium adalah bererti menurut lokasi (p<0.05) bagi kedua-dua jantina. Semakin jauh lokasi dari pusat bandaraya Kuala Lumpur, semakin tinggi paras selenium subjek. Kesimpulannya, paras selenium serum populasi penduduk di Daerah Hulu Langat adalah normal berbanding nilai rujukan dari Makmal Unsur Surih, Institut Robens, University of Surrey iaitu 0.89-1.65 μmol/l untuk dewasa.
  4. Ismarulyusda Ishak, Penny George, Farah Wahida Ibrahim, Hanis Mastura Yahya, Nor Farah Mohamad Fauzi
    Jurnal Sains Kesihatan Malaysia, 2018;16(101):105-111.
    MyJurnal
    Postprandial hyperglycemia is independently related to cardiovascular disease. Garlic, ginger, lemon, honey and apple cider vinegar are known to have anti-glycemic properties. However, the effectiveness of combination of these natural products on reducing postprandial glycemia is uncertain. The aim of the present study was to investigate the glucose-lowering effect of a novel mixture consisting of apple cider vinegar, garlic, ginger, lemon, and honey; alone and in combination with exercise in response to a high-carbohydrate meal in non-diabetic individuals. Ten, female subjects (mean age: 25 ± 2.67 years, mean BMI: 22.6 ± 3.5 kg/m2) participated in this randomised, cross-over intervention consisting of four trials: control (CON), mixture only (MIX), exercise only (EX), and exercise + mixture (EX-MIX). All trials involved consumption of a high-carbohydrate breakfast, then followed by rest in CON, consumption of natural product mixture in MIX, brisk-walking exercise in EX, and combination of mixture and exercise in EX-MIX. Blood glucose was measured at fasting, and at 30, 60, 90, 120 minutes post meal. Postprandial glucose response was calculated as area under the glucose curve. Two-way repeated measures ANOVA showed a significant group and time interaction (p < 0.001). Compared to CON, postprandial glucose responses were 8%, 13% and 15% lower in MIX (p = 0.049), EX (p = 0.001) and EX-MIX (p = 0.005) respectively. Postprandial glucose was 8% lower in EX-MIX compared to MIX (p = 0.002). In conclusion, consuming natural product mixture containing garlic, ginger, lemon, honey and apple cider vinegar reduced postprandial glycemia to a certain extent, however, combining mixture with exercise produced a greater attenuation effect compared to consuming mixture alone. This finding is indicative of a potential benefit of the novel mixture as a complementary management of hyperglycemia in high-risk individuals.
  5. Siti Fathiah Masre, Nurul Farhana Jufri, Nur Zakiah Mohd Saat, Syarif Husin Lubis, Ismarulyusda Ishak
    Jurnal Sains Kesihatan Malaysia, 2018;16(101):113-117.
    MyJurnal
    Motivation camp is one of the learning interventions to assist underperform students in improving their academic performances in term of GPA (Grade Point Average). An intervention study was carried out to know the effectiveness of a motivation camp in improving the academic performances among the biomedical science students at the Universiti Kebangsaan Malaysia, Kuala Lumpur. Total of 44 respondents were involved in this study from year 2 and year 3 and had been categorized into control and intervention groups (n = 22 per group). The intervention group was given motivational talks followed by a group discussion and self-reflection. The students in the intervention group were also assigned with academicians to facilitate and guide them throughout the motivational camp. The students were interested in motivational talks activity the most. The average GPA showed a significant improvement after the motivation camp with 3.01 ± 0.30 (p < 0.05) for the intervention group. Yet, control group also displayed a significant increment in the average GPA, 3.24 ± 0.06 (p < 0.05). In conclusion, motivation camp is one of the many learning intervention tools that strategize to help students in improving their academic performances but it should be complemented with other intervention methods.
  6. Zul-‘Izzat Ikhwan Zaini, Norhafizah Karim, Ismarulyusda Ishak, Hidayatulfathi Othman, Wei, Lei Hum
    Jurnal Sains Kesihatan Malaysia, 2019;17(3):127-137.
    MyJurnal
    In Malaysia, dengue fever is a common vector-borne disease. Most cases of dengue fever are reported in residential areas. Children are at high risk to be infected because they spend a lot of time around their housing area for outdoor activities. Such areas may have a high number of Aedes mosquitoes. As schools are equipped with infrastructure and medium for effective educational purposes, schools represent the most suitable facilities for learning and teaching process. A crosssectional study was conducted to determine the level of knowledge among students in Hulu Langat on Aedes mosquitoes, dengue fever, and Zika virus. The study also reported on the demographic factors which affected the knowledge level. Based on sample size calculation using G*Power v3.1 software, a total of 171 respondents were needed from the two primary schools involved in the study. Data collection was conducted using a pre-tested questionnaire that consisted of two main sections on demography and knowledge about Aedes mosquitoes, dengue fever and Zika virus. From the total score of 55, the mean knowledge score is 34.2 ± 8.38. Based on the median value of 36.0, about 50.9% of respondents had satisfactory knowledge. From the study, it was found that students from School A, students who had been watching video related to Aedes mosquito, and those with history of dengue infection among family members had a significantly better knowledge score (p < 0.01). In conclusion, knowledge about Aedes mosquitoes and related illnesses need to be enhanced through a comprehensive module and effective educational materials that can serve as a reliable source of information for primary school students.
  7. Siti Nor Ismalina Isa, Nur Zakiah Mohd Saat, Syarif Husin Lubis, Muhammad Faiz Mohd Ismail, Ismarulyusda Ishak
    MyJurnal
    Parents or caregivers of children with learning disabilities have been shown to experience increases in stress and greater negative caregiving consequences than those with typically developing children. The current study sought to assess the perceived stress among Malay caregivers of children with learning disabilities in Kelantan. The Malay version of Perceived Stress Scale 10 items was administered to a sample of 40 caregivers of children with learning disabilities who were registered to five Pusat Pemulihan Dalam Komuniti (PDK) in Kelantan. Higher scores indicate higher levels of stress. The caregivers had mean age of 47.68 (SD = 9.18) years old, of whom 90% were fathers or mothers. Ninety percent of them were married, majority were unemployed or housewives and had secondary school education. The majority of children with learning disabilities were males and half of them were Down Syndrome children. The mean total Perceived Stress Scale score of the caregivers was 16.77 (SD = 5.74). There were no significant associations between total perceived stress score and any of the independent variables. The mean total perceived stress score showed that the perceived stress level was in the category of slightly higher than average and health concern level was high, while the average stress level was between score of 12 to 15. In conclusion, this result indicated that the caregivers had slightly higher levels of stress than the average score, and might increase susceptibility to stress-induced illness.
  8. Heo, Chong Chin, Mohamad Abdullah Marwi, Jeffery, John, Sofian-azirun, M., Chen, Chee Dhang, Wan Omar Abdullah, et al.
    MyJurnal
    An entomological study was conducted in Tanjung Sepat, Selangor, Malaysia in May until September 2007 revealing five species of butterflies (all from family Nymphalidae) were attracted to pig carcasses placed in an oil palm plantation. Euploea mulciber (Cramer 1777), Hypolimnas bolina (Linnaeus 1758), Elymnias hypermnestra (Linnaeus 1763), Mycalesis mineus (Linnaeus 1758) and Ypthima baldus (Fabricius 1775) came to the carcasses at different stages of decomposition. From this study, we know that nymphalid butterflies are attracted to carcasses but their roles are most probably unimportant in post-mortem estimation.
  9. Zariyantey Abdul Hamid, Zaliha Harun, Syarif Husin Lubis, Nihayah Mohamed, Ismarulyusda Ishak, Hidayatul Fathi Othman, et al.
    MyJurnal
    Health awareness promotion among farming communities are important for a sustainable agriculture activities. A cross-sectional study was conducted to assess health status among farming communities in Cameron Highlands, Pahang (n = 61) and Bachok and Pasir Puteh, Kelantan (n = 143). Mobile Health Screening Programme composed of assessment of blood glucose, blood cholesterol, haemoglobin, blood pressure, pterygium, lung function and nerve conductive velocity was utilized. Our results indicate that the percentage of Cameron Highland’s farmers with hyperglycaemia, systolic hypertension, diastolic hypertension and anaemia were 8.2%, 14.8%, 11.5% and 8.2%, respectively. However, higher percentage of farmers in Bachok and Pasir Puteh, Kelantan with hyperglycaemia (32.8%), hypercholesterolaemia (83%), anaemia (24.2%) and systolic hypertension (41.9%) were observed. Pterygium was positive for 88.6% of farmers in Cameron Highlands and 94.4% in Bachok and Pasir Puteh. Lung function test shows that 61.7% and 11.4% of farmers in Cameron Highlands had restrictive and obstructive lung, respectively. In Bachok and Pasir Puteh, a total of 19.8%, 55.5% and 23.9% of farmers were found to have obstructive, restrictive and combined obstructive and restrictive lung, respectively. Current Perception Threshold (CPT) value which indicate nerve conductive velocity were significantly increased (p < 0.05) among Cameron Highland’s farmers for both median and peroneal nerve at all frequencies (5 Hz, 250 Hz and 2000 Hz). In Bachok and Pasir Puteh, the values of the CPT for median nerve was significantly increased (p < 0.05) for all frequencies (5, 250 and 2000 Hz). Meanwhile, a signifi cant increased (p < 0.05) was observed for the CPT values for peroneal nerve at the frequencies of 250 and 2000 Hz as compared to control groups. In conclusion, analysis revealed different health problem among the studied farming communities which could be influenced by the differences in farming practices. Thus, employed Mobile Health Screening Programme offers a monitoring approach that could highlight the need for suitable health services and awareness programmes for different farming communities.
  10. Nurfariha Firdaus, Ismarulyusda Ishak, Syarif Husin Lubis, Nooraisyah Mansoor, Hidayatul Fathi Othman, Nihayah Mohammad, et al.
    MyJurnal
    Kromium merupakan mineral yang penting dan kofaktor insulin yang memainkan peranan penting sebagai hormon yang membantu dalam regulasi gula dalam darah. Penduduk Kelantan sering dikaitkan dengan pengambilan makanan berasaskan gula. Petani merupakan golongan yang berisiko tinggi kerana pendedahan terhadap pestisid dan pengambilan makanan bergula boleh mempengaruhi paras kromium. Objektif kajian ini adalah untuk mengetahui status paras kromium dalam kalangan petani yang terdedah kepada pestisid dan baja kimia di Kelantan. Kajian ini adalah kajian keratan rentas yang dilakukan di Bachok dan Pasir Puteh, Kelantan. Responden adalah seramai 113 petani yang terdedah kepada pestisid atau baja kimia tidak kurang daripada satu tahun. Subjek ditemu bual menggunakan soal selidik pengetahuan, sikap dan amalan (KAP) yang telah divalidasi untuk informasi berkaitan data demografi k. Sampel kuku dan rambut telah dianalisia dengan menggunakan kaedah pencernaan asid dan Inductively Coupled Plasma Mass Spectroscopy (ICPMS) untuk mendapatkan paras kromium. Hasil kajian menunjukkan 81.4% adalah petani lelaki dan 18.6% adalah perempuan. Paras kromium kuku (125.82 ± 47.81 μg/L) dan rambut (39.63 ± 5.70 μg/L) petani adalah lebih rendah berbanding julat piawai kuku (6200 μg/L) dan rambut (100-2500 μg/L). Tiada perbezaan paras kromium yang signifi kan (p > 0.05) menurut jantina, umur, glukosa darah, tempoh pendedahan pestisid dan pemakanan. Petani yang merokok menunjukkan paras kromium yang lebih rendah (p < 0.05) berbanding petani yang tidak merokok. Kesimpulannya, paras unsur kromium petani di Bachok dan Pasir Puteh adalah rendah berbanding julat normal dan petani harus berhenti merokok kerana merokok akan merendahkan paras kromium.
  11. Ahmad Rohi Ghazali, Maziani Abdullah, Asmah Hamid, Asmariah Ahmad, Tava Shelan Nagapan, Ismarulyusda Ishak, et al.
    MyJurnal
    Pesticides and chemical fertilizers are widely used in agriculture to increase crop productivity among farmers. However, exposure to pesticides will give potential risk to human health. The aim of this study was to analyze the frequency of micronucleus (MN) and binucleus (BNu) formation in buccal cells from farmers who were exposed to pesticides using the MN assay. Buccal swabs were collected from the farmers in Tanjung Karang (n = 32) and Kelantan (n = 43) using wooden tongue depressor. A structured questionnaire was used to obtain demographic data of the farmers. Cytogenetic analysis was carried out by Acridin Orange (AO) staining 0.0025% (w/v). The frequency of MN and BNu as the biomarkers for cytogenetic damage was observed by using a fluorescence microscope. Comparison of frequency of MN and BNu is conducted in two areas namely Tanjung Karang, Selangor and Kelantan because of the agricultural activity and the type of pesticides used are different. Results showed that the frequencies of both MN and BNu among farmers in Tanjung Karang were significantly higher (p < 0.05) compared to farmers in Kelantan. Meanwhile, for the socio-demographic factors (age, smoking status, working period), MN and BNu frequencies among farmers in Tanjung Karang were also significantly higher (p < 0.05) as compared to farmers in Kelantan. While in the aspect of pesticide exposure, the frequencies of MN and BNu showed no significant difference between the frequency of pesticide spraying (p > 0.05) and the practices of PPE (Personal Protective Equipment) (p > 0.05). This may suggests that cytogenetic changes were not influenced by these factors. In addition, correlation study shows positive correlation between the frequency of MN with the pesticide exposure of farmers in Tanjung Karang (p > 0.05, r = 0.015) and Kelantan (p > 0.05, r = 0.0158). Besides, the frequency of BNu also has a positive correlation with the pesticide exposure among farmers in Tanjung Karang (p > 0.05, r = 0.036) and farmers in Kelantan (p > 0.05, r = 0.013). Hence, this present study demonstrated that exposure to pesticides increased the formation of MN and BNu among farmers and the prolonged use of pesticides may induce genotoxicity and DNA damage to human
  12. Ismarulyusda Ishak, Farah Wahida Ibrahim, Santibuana Abd Rahman, Nor Malia Abd Warif, Ahmad Rohi Ghazali, Faisal Ariffin, et al.
    Jurnal Sains Kesihatan Malaysia, 2018;16(101):129-136.
    MyJurnal
    Tahfiz education has been well accepted by Muslims in Malaysia. Memorizing the Quran through rote learning can assist in improving the brain ability to process, store information and build memory. In addition, dietary intakes were reported to contribute in the process of memorizing the Quran and to increase the levels of intelligence (IQ) among huffaz students. This cross-sectional study was conducted to measure and to determine the correlation between IQ and dietary intake as well as between IQ and the level of trace elements among students in selected tahfiz schools and non-tahfiz school in Selangor. Questionnaires were used to obtain demographic data. Dietary intake was assessed via 3 days dietary record. Levels of trace elements in the nail samples were analyzed by using ICP-MS. Test for intelligence using WASI-II was conducted to measure the students’ IQ. The results showed that there was a moderate positive correlation between IQ and carbohydrate (r = 0.425, p < 0.001, a weak positive correlation between IQ and energy (r = 0.260, p < 0.05), vitamin B6 (r = 0.189, p < 0.05), vitamin B12 (r = 0.207, p < 0.05) and vitamin C (r = 0.211, p < 0.05). The levels of trace elements in nail samples showed no correlation with IQ, whereas there were moderate positive correlations between IQ and dietary zinc (r = 0.375, p < 0.001) as well as between IQ and dietary iron (r = 0.303, p < 0.001). There was also a moderate positive correlation between IQ and the level of memorization (r = 0.375, p < 0.001). The results of stepwise multiple linear regression showed that al-Quran memorization influence the level of IQ by 20 %. As a conclusion, dietary intake of certain nutrients including energy, vitamins and selected trace elements can potentially improve memorization activities and also IQ.
  13. Santibuana Abd Rahman, Ismarulyusda Ishak, Nor Malia Abd Warif, Farah Wahida Ibrahim, Ahmad Rohi Ghazali, Normah Che Din, et al.
    MyJurnal
    Kajian terdahulu menunjukkan kualiti hidup dapat ditingkatkan melalui amalan keagamaan dan kerohanian. Hafazan al-Quran merupakan amalan keagamaan dan kerohanian yang memperkasa aspek mental dan fizikal. Namun, kajian saintifik yang mengaitkan hafazan al-Quran dengan kualiti hidup masih terhad terutamanya dalam konteks pelajar tahfiz. Maka, kajian ini bertujuan untuk mengenal pasti hubungan antara hafazan al-Quran dengan kualiti hidup dalam kalangan pelajar tahfiz di Selangor, Malaysia. Satu kajian keratan rentas telah dijalankan ke atas 116 pelajar dengan pensampelan rawak berstrata dari tiga buah sekolah tahfiz di Selangor. Pelajar tahfiz dikategorikan kepada tiga tahap hafazan berdasarkan jumlah juzuk yang telah dihafaz iaitu Tahap 1 (1-10 juzuk), Tahap 2 (11-20 juzuk) dan Tahap 3 (21-30 juzuk). Borang soal selidik telah digunakan untuk mendapatkan data sosiodemografi dan borang soal selidik Short Form-36 Quality of Life (SF-36) versi Bahasa Malaysia telah digunakan untuk menilai tahap kualiti hidup. Data telah dianalisa menggunakan SPSS versi 23.0. Hasil kajian mendapati wujud hubungan positif yang signifikan antara hafazan al-Quran dengan kesihatan fizikal (r = 0.300, p < 0.05) dan kesihatan mental (r = 0.194, p < 0.05). Ini jelas menunjukkan bahawa semakin banyak pelajar menghafaz al-Quran semakin tinggi tahap kualiti hidup mereka. Faktor yang mempengaruhi kesihatan mental dan fizikal adalah jumlah muka surat hafazan. Kesimpulannya, hafazan al-Quran berpotensi meningkatkan kualiti hidup serta kesihatan mental dan fizikal pelajar tahfiz.
  14. Siti Fathiah Masre, Ismarulyusda Ishak, Arimi Fitri Mat Ludin, Asma Afifah Shamhari, Syed 'Imran Syed Idro, Nur Adilah Abdul Rahman, et al.
    MyJurnal
    Background: Time management is one of the factors that may influence students’ academic performance in university. A cross-sectional study was carried out to evaluate the role of motivation camp programme towards time management among first-year undergraduate students of the Biomedical Science Programme, Universiti Kebangsaan Malaysia (UKM) by using a questionnaire. Methods: A total of 32 students was categorized into group 1 and group 2 (n=16 per group), with group 1 is students who did not attend the motivational camp and group2 participated in the camp. Their academic performance in terms of Grade Point Average (GPA) was evaluated in semester 1 and 2 of the 2017/2018 session. A correlation test between total study hours and GPA in both semesters showed a weak correlation for group1 and group2. Independent T-test was also carried out to compare time management and GPA. Results: There is no significant difference between group1 and group2 in time planning; however, there is a significant difference (p
  15. Ismarulyusda Ishak, Hidayatulfathi Othman, Nihayah Mohammad, Syarif Husin Lubis, Zariyantey Abdul Hamid, Nur Zakiah Mohd Saat, et al.
    MyJurnal
    Pendedahan terhadap pestisid dapat menyebabkan penurunan paras unsur surih di dalam badan manusia. Unsur surih memainkan peranan penting dalam metabolisma tubuh. Kajian ini dijalankan untuk mengkaji paras unsur surih selenium, zink dan kromium dalam kalangan pesawah yang terdedah kepada pestisid di Wilayah I, MADA, Perlis. Kajian keratan rentas ini melibatkan 70 orang pesawah dan 57 orang yang tinggal di perkampungan nelayan sebagai kumpulan kawalan yang berumur di antara 21 hingga 80 tahun. Maklumat sosiodemografi pesawah dilakukan melalui temuduga borang soal selidik yang telah divalidasi. Pemeriksaan tekanan darah dan glukosa darah pesawah dilakukan. Paras selenium, zink dan kromium sampel kuku dan rambut dianalisis dengan menggunakan kaedah penghadaman asid dan mesin Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). Hasil kajian mendapati bahawa paras selenium pada rambut (5.11 ± 17.05 μg/L) dan kuku (4.92 ± 2.17 μg/L) adalah lebih rendah secara signifikannya (p < 0.05) berbanding paras selenium pada rambut (15.67 ± 10.59 μg/L) dan kuku (6.67 ± 2.81 μg/L) kumpulan kawalan. Paras kromium pada rambut (31.83 ± 15.17 μg/L) dan kuku (87.64 ± 23.30 μg/L) kumpulan pesawah juga didapati lebih rendah secara signifikannya (p < 0.05) berbanding paras kromium pada rambut (85.19 ± 56.90 μg/L) dan kuku (99.36 ± 56.89 μg/L) pada kumpulan kawalan. Walau bagaimanapun, tiada perbezaan paras unsur surih yang signifikan (p > 0.05) menurut tempoh pendedahan pestisid. Kesimpulannya, paras selenium dan kromium pada kuku dan rambut pesawah yang terdedah kepada pestisid adalah lebih rendah berbanding kumpulan komuniti nelayan.

  16. Asmah Hamid, Kholilul Syafiq Baharuddin, Nor Fadilah Rajab, Syarif Husin Lubis, Ismarulyusda Ishak, Nur Zakiah Mohd Saat, et al.
    MyJurnal
    Pesticide exposure may cause genotoxic effects by inducing the formation of micronucleus (Mn). Mn are fragments of chromosomes that remains after cells division. The increase in Mn may increase the risk of cancer formation. Our study aimed to determine the effects of lifestyle and pesticide exposure on the formation of Mn in epithelial cells from buccal swabs among paddy farmers in Malaysia. About 40 farmers who were exposed to pesticides were chosen as subjects and 30 personnels whose not directly exposed to pesticides, were chosen as the control group. Demographic and anthropometric data were obtained from questionnaires developed. Analysis of Mn formation was done using Giemsa staining (10% v/v) and the frequency of Mn formation was scored from 1000 cells per sample. Kruskal-Wallis test done between Mn frequency with age group showed a significant increase (p < 0.05) in Mn frequency in farmers as compared to the control in the age group of 30-39 , 40-49 years, and 50-59 years. Significant increased (p < 0.05) were observed between Mn frequency groups of normal BMI, pre-obese, and grade 1 obese as compared to control. Significant increase of Mn frequency (p < 0.01) was also seen among smokers and farmer’s group (15.39 ± 3.34) as compared to controls (4.76 ± 1.26). The maximum numbers of Mn found in farmers are 7 Mn per cell whereas for control group is only 3 Mn. However, most farmers had only 1 Mn (81.75 ± 6.42%) and 2 Mn (15.28 ± 5.14%). Mn frequency with the duration of exposure to pesticides in a month and the use of PPE revealed no significant difference (p = 0.27). In conclusion, the increased frequency of Mn was influenced by age, gender, BMI and smoking status of farmers besides commonly repeated duration of exposures and the use of PPE. Further studies are needed to analyze the causes of an increased in Mn among farmers.
  17. Ahmad Rohi Ghazali, Ismarulyusda Ishak, Farah Wahida Ibrahim, Nor Malia Abd Warif, Mohd Jamil Mohd Rafaai, Faisal Ariffin, et al.
    Jurnal Sains Kesihatan Malaysia, 2019;17(2):135-146.
    MyJurnal
    Sekolah tahfiz merupakan institusi yang mengkhususkan pendidikan kepada pelajar yang boleh menghafaz serta mengingati keseluruhan al-Quran. Aktiviti menghafaz al-Quran dengan teknik pengucapan berulang kali akan membantu meningkatkan keupayaan otak untuk memproses, mengingati maklumat dan membina memori. Kehadiran logam berat akan memberi kesan kepada sistem saraf serta mengganggu fungsi sistem saraf pusat dan periferi di mana akan seterusnya menyebabkan berlakunya kecelaan fungsi mental dan kognitif. Keupayaan untuk belajar, mengingati atau menghafaz, penggunaan bahasa dan untuk memahami sesuatu akan terganggu serta mengurangkan IQ dan perhatian. Kajian keratan rentas telah dilakukan bagi mengukur dan mengenal pasti hubungan di antara tahap logam berat, hafazan al-Quran dan tahap kecerdasan (IQ) dalam kalangan pelajar di sekolah tahfiz berbanding sekolah bukan tahfiz terpilih di Selangor. Kepekatan logam berat ditentukan melalui analisa sampel kuku dan rambut pelajar dengan menggunakan Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Ujian kecerdasan Wechsler Adult Intelligence Scale Edisi Kedua (WASI-II) digunakan untuk mengukur IQ pelajar. Borang soal selidik yang digunakan untuk mengumpulkan data demografik dianalisa menggunakan SPSS versi 23.0. Berdasarkan ujian korelasi Pearson yang dilakukan, terdapat korelasi negatif yang sangat lemah tetapi signifikan antara logam mangan dalam sampel rambut dengan tahap hafazan al-Quran (r = -0.178, p = 0.017). Selain itu, terdapat korelasi positif yang lemah tetapi signifikan antara IQ dengan tahap hafazan al-Quran (r = 0.375, p = < 0.001). Kesimpulannya, semakin tinggi kepekatan logam mangan akan menyebabkan penurunan tahap hafazan al-Quran serta apabila semakin tinggi tahap hafazan al-Quran akan menyebabkan tahap kecerdasan (IQ) juga semakin meningkat.
  18. Nur Zakiah Mohd Saat, Ismarulyusda Ishak, Syarif Husin Lubis, See, Huong Wen, Siti Nor Lily Suriyanee Mohd, Norul Sahira Zakaria, et al.
    ASEAN Journal of Psychiatry, 2010;11(2):190-197.
    MyJurnal
    Objective: The objective of this study was to assess the relationship between stress score and body mass index (BMI) of students of Science in Kuala Lumpur. Methods: A cross-sectional study was carried out among 126 students. Data about stress score were collected using a questionnaire, the Student-Life Stress Inventory (SLSI) Data about BMI were calculated from height and weight of the respondents. Results: A total of 117 (92.85%) out of 126 students had responded. The mean difference of stress score among first, second and third year students were 87.6 ± 17.0, 83.4 ± 16.9 and 86.7 ± 15.4 respectively. The mean difference of stress scores between the Bumiputra and non-Bumiputra students were 87.9 ± 16.5 and 83.2 ± 15.9 .The mean of body mass Index(BMI) between first, second and third year students were 21.0 ± 3.5, 20.3 ± 2.7 and 21.8 ± 4.3 respectively. Conclusions: This study showed that the stress level is higher in first year, female and bumiputra student. There was no significant relationship between stress score and BMI.
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