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Fulltext The prevalence of denture wearing and the impact on the oral health related quality of life among elderly in Kota Bharu, Kelantan

Zainab, S., Ismail, N.M., Norbanee, T.H., Ismail, A.R.

Archives of Orofacial Sciences, 2008;3(1):17-22.
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This study aims to determine the prevalence of denture wearing among elderly and to compare the oral health related quality of life (OHRQoL) between elderly with dentures and those without dentures. This cross sectional study involved 506 randomly selected edentulous elderly in the district of Badang, Kota Bharu, Kelantan. Consented participants were interviewed in the Kelantanese dialect at their homes by a single trained interviewer using the short version Oral Health Impact Profile [S-OHIP(M)] which had been translated into the Malay language, tested and validated for use in Malaysian population. Denture wearing and self rated denture status was noted. The prevalence of denture wearing was 46.2% (95% CI=41.83, 50.70). There was a significant difference in sex, smoking status, self perceived treatment need and self perceived satisfaction between denture wearers and non denture wearers. Denture wearers reported better overall OHRQoL compared to non denture wearers (p
Fulltext Surface modification of hybrid composite multilayers spin cold spraying for biomedical duplex stainless steel

Fahad ND, Radhi NS, Al-Khafaji ZS, Diwan AA

Heliyon, 2023 Mar;9(3):e14103.
PMID: 36938400 DOI: 10.1016/j.heliyon.2023.e14103

The performance of biomaterials in biological systems is of critical significance for advancing biomedical implants. Duplex Stainless Steel alloys are the major biomaterials due to their significant characteristics. Many functional coatings are deposited on DSS alloy surfaces utilizing numerous surface coating techniques to improve their bioactivity and protect them from corrosion degradations. Coatings of titanium dioxide (TiO2), Hydroxyapatite (HA), and zinc oxide (ZnO) have received considerable attention in the field of surface bioactive modification of DSS alloy implants. The coating techniques play a key role in increasing the required biological characteristics of DSS alloys, such as biocompatibility, mechanical properties, and corrosion resistance. In this regard, HA-ZnO, HA-TiO2, and TiO2-ZnO from each coating group are divided into single, double, and triple layers. These coatings were prepared by cold spray and deposited on the surface of the DSS alloy, followed by a heat treatment at 250 °C. The surface morphology of coated surfaces was analyzed utilizing field emission scanning electron microscopy (FESEM), atomic force microscopic (AFM), microhardness test, corrosion test in Ringer solution, and antibacterial test. The coatings showed nano-scale surface morphology with advanced crystallization and homogeneous structures; in the corrosion characteristics utilizing potentiodynamic polarization, triple layers of HA-ZnO coatings displayed advanced nanostructures with higher hardness values (514.75HV). The antibacterial test showed the triple layers of HA-TiO2 and two layers of TiO2-ZnO sensitivity to positive bacteria.
Fulltext Maternal passive smoking and its effect on maternal, neonatal and placental parameters

Ramesh KN, Vidyadaran MK, Goh YM, Nasaruddin AA, Jammal ABE, Zainab S

Med J Malaysia, 2005 Aug;60(3):305-10.
PMID: 16379184

A study was undertaken to 1) determine the effects of tobacco smoke exposure on maternal and neonatal weight and body mass index (BMI) and placental weight, volume and surface area and 2) establish any correlations between the placental surface area, volume and weight with maternal and neonatal body weight and BMI in mothers exposed to cigarette smoke. A total of 154 full-term placentae, 65 from mothers exposed to tobacco smoke and 89 from non-exposed mothers were collected from Kuala Lumpur Maternity Hospital. The placental surface area was determined using a stereological grid, the volume by Scherle's method and the weight by using an electronic weighing machine. In general there were no differences in maternal, placental and neonatal parameters between the exposed and non-exposed groups. However, there were significant correlations between placental weight with maternal weight and maternal BMI in both exposed (r = 0.315; p = 0.013) and (r = 0.265; p = 0.038), and non-exposed (r = 0.224; p = 0.035) and (r = 0.241; p = 0.023) mothers. It was also found that the maternal weight on admission correlated significantly with placental weight in both Malay (r = 0.405; p = 0.020) and Indian (r = 0.553; p = 0.050) passive smokers. Correcting the placental parameters for the maternal weight had no effect on the results.
Weight, volume and surface area of placenta of normal pregnant women and their relation to maternal and neonatal parameters in Malay, Chinese and Indian ethnic groups

Sivarao S, Vidyadaran MK, Jammal AB, Zainab S, Goh YM, Ramesh KN

Placenta, 2002 10 4;23(8-9):691-6.
PMID: 12361688

This study was conducted to determine the effect of ethnicity on maternal, placental and neonatal parameters. Maternal, placental, and the newborn parameters were corrected for gestational age. The male:female sex ratio was 1:1.03. One hundred and forty-four freshly delivered placentae from 55 Malaysian, 51 Chinese, and 38 Indian normal healthy patients were collected and standard stereological methods used to estimate the placental parameters. Pearson's correlation, Spearman's correlation and 1-way ANOVA were used to test significance of differences. Placental surface area, placental weight and placental volume of Indians were lower than Malays (P< 0.05). Placental weight correlated significantly with neonatal length (r=0.527), birthweight (r=0.665), head circumference (r=0.371) and booking weight (r=0.193) while placental volume correlated with neonatal length (r=0.588), birthweight (r=0.688), head circumference (r=0.384), parity (r=0.202) and booking weight (r=0.219) at P< 0.05. Indian babies weight and length were less than Chinese and Malay babies (P< 0.05) while booking weight of Indian mothers was less than those of Chinese mothers (P< 0.05). Even after being corrected for booking weight, placental parameters of Indian patients were still significantly less than Malays and Chinese (P< 0.05).
Fulltext Genomic analysis of methicillin-resistant Staphylococcus aureus strain SO-1977 from Sudan

Ali MS, Isa NM, Abedelrhman FM, Alyas TB, Mohammed SE, Ahmed AE, et al.

BMC Microbiol, 2019 06 11;19(1):126.
PMID: 31185900 DOI: 10.1186/s12866-019-1470-2

BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is known as a leading cause of morbidity and mortality. Investigation of the MRSA's virulence and resistance mechanisms is a continuing concern toward controlling such burdens through using high throughput whole Genome Sequencing (WGS) and molecular diagnostic assays. The objective of the present study is to perform whole-genome sequencing of MRSA isolated from Sudan using Illumina Next Generation Sequencing (NGS) platform.
RESULTS: The genome of MRSA strain SO-1977 consists of 2,827,644 bp with 32.8% G + C, 59 RNAs and 2629 predicted coding sequences (CDSs). The genome has 26 systems, one of which is the major class in the disease virulence and defence. A total of 83 genes were annotated to virulence disease and defence category some of these genes coding as functional proteins. Based on genome analysis, it is speculated that the SO-1977 strain has resistant genes to Teicoplanin, Fluoroquinolones, Quinolone, Cephamycins, Tetracycline, Acriflavin and Carbapenems. The results revealed that the SO-1977, strain isolated from Sudan has a wide range of antibiotic resistance compared to related strains.
CONCLUSION: The study reports for the first time the whole genome sequence of Sudan MRSA isolates. The release of the genome sequence of the strain SO-1977 will avail MRSA in public databases for further investigations on the evolution of resistant mechanism and dissemination of the -resistant genes of MRSA.