Singapore is a small Southeast Asian island city-state located at the tip of the Malay peninsula with a population of 5.61 million people. It was a former British colony that went on to become a part of Malaysia before gaining independence in 1965. Since then, Singapore has developed tremendously from a small fishing village into the region's medical hub. This article will explore the roots of cardiac anesthesia in Singapore and how it has developed into a subspecialty today.
Coca-leaf habituation has affected millions of Andean natives for over 400 years. In the last half-century it has also involved millions more Malayans. Coca leaf, from which cocaine and extracts for some commercial carbonated soft drinks are obtained, remains relatively unknown by the medical and allied professions elsewhere. A review of the original medical, historical and other pertinent literature of the last 350 years illustrates the origins of the use of coca leaf, its spread, the isolation of cocaine and its first uses, as well as some of the euphoric and other effects of both substances.