Displaying publications 1 - 20 of 46 in total

  1. HONG YG
    Med J Malaya, 1955 Mar;9(3):222-6.
    PMID: 14393213
    Matched MeSH terms: Infant, Newborn, Diseases*
  2. Salleh HM
    Med. J. Malaysia, 1973 Sep;28(1):40-3.
    PMID: 4273783
    Matched MeSH terms: Infant, Newborn, Diseases*
  3. Kwan PW, Khoo BH, Lam KL, Puthucheary SD
    Med. J. Malaysia, 1979 Sep;34(1):71-5.
    PMID: 396463
    Matched MeSH terms: Infant, Newborn, Diseases*
  4. Khoo BH
    Med. J. Malaysia, 1978 Jun;32(4):297-301.
    PMID: 732626
    Matched MeSH terms: Infant, Newborn, Diseases/diagnosis*
  5. Laidin AZ, Mohd Nor M, Abdul Wahab Y, Mahamooth Z
    Med. J. Malaysia, 1982 Sep;37(3):281-9.
    PMID: 7177013
    Over the six-veer periodfrom. 1976 to 1981, there were 241 neonates referred to the U.K.M. Paediatric Surgical Unit, General Hospital, Kuala Lumpur for alimentary tract obstruction and 207 were operated on. The three commonest conditions were anorectal anomalies (91 cases), Hirschsprung's disease (31 cases) and oesophageal atresia (30 cases). Overall operatioe mortality was 28.0 percent. This was high when preoperative complications lihe gut perforation (88.9 percent) or pneumonia (61.9 percent) and associated severe anomalies (90.9 percent) or chromosomal abnormalities (66.7 percent) were present. Emphasis is placed on the establishment of early diagnosis and the significance of the green vomit and maternal hydramnios is highlighted, The need is felt for more specialised nurses and the creation of a separate neonatal ICU in this hospital.
    Matched MeSH terms: Infant, Newborn, Diseases/surgery*
  6. Yong YF
    Med. J. Malaysia, 1983 Mar;38(1):74-6.
    PMID: 6688850
    Tetanus, especially tetanus neonatorum (T.N.) continues to be a significant medical and social problem in the developing countries. The case mortality rate remains very high even in the 'developed' countries, varying from 60-80 percent in various reports, and even higher in the case of tetanus neonatorum. Sanders et al had introduced the method of intrathecal injection of antitetanus serum (ATS) in 1976 and have achieved very encouraging results. As the conventional treatment of tetanus neonatorum had achieved very poor result, even in the very sophisticated centres, a case of tetanus neonatorum admitted to Cottage Hospital Semporna in Sabah had been treated with intrathecal ATS since June 1982. This paper reviews the results of this new approach to tetanus neonatorum treatment as compared to cases treated conventionally.
    Matched MeSH terms: Infant, Newborn, Diseases/therapy*
  7. Lee EL, Khoo BH, Lam KL
    Med. J. Malaysia, 1978 Mar;32(3):220-4.
    PMID: 683047
    Matched MeSH terms: Infant, Newborn, Diseases/therapy*
  8. Lopez CG, Lie-Injo Luan Eng
    Hum. Hered., 1971;21(2):185-91.
    PMID: 5127409
    Matched MeSH terms: Infant, Newborn, Diseases/blood; Infant, Newborn, Diseases/genetics; Infant, Newborn, Diseases/epidemiology*
  9. Malarvili MB, Mesbah M
    IEEE Trans Biomed Eng, 2009 Nov;56(11):2594-603.
    PMID: 19628449 DOI: 10.1109/TBME.2009.2026908
    In this paper, we investigate the use of heart rate variability (HRV) for automatic newborn seizure detection. The proposed method consists of a sequence of processing steps, namely, obtaining HRV from the ECG, extracting a discriminating HRV feature set, selecting an optimal subset from the full feature set, and, finally, classifying the HRV into seizure/nonseizure using a supervised statistical classifier. Due to the fact that HRV signals are nonstationary, a set of time-frequency features from the newborn HRV is proposed and extracted. In order to achieve efficient HRV-based automatic newborn seizure detection, a two-phase wrapper-based feature selection technique is used to select the feature subset with minimum redundancy and maximum class discriminability. Tested on ECG recordings obtained from eight newborns with identified EEG seizure, the proposed HRV-based neonatal seizure detection algorithm achieved 85.7% sensitivity and 84.6% specificity. These results suggest that the HRV is sensitive to changes in the cardioregulatory system induced by the seizure, and therefore, can be used as a basis for an automatic seizure detection.
    Matched MeSH terms: Infant, Newborn, Diseases/diagnosis*; Infant, Newborn, Diseases/physiopathology
  10. Sinniah D, Sandiford BR, Dugdale AE
    Clin Pediatr (Phila), 1972 Dec;11(12):690-2.
    PMID: 4639314
    Matched MeSH terms: Infant, Newborn, Diseases/etiology; Infant, Newborn, Diseases/epidemiology*
  11. van Vliet E, Dijkema GH, Schuit E, Heida KY, Roos C, van der Post J, et al.
    BJOG, 2016 Oct;123(11):1753-60.
    PMID: 27550838 DOI: 10.1111/1471-0528.14249
    BACKGROUND: Preterm birth is the leading cause of neonatal mortality and morbidity in developed countries. Whether continued tocolysis after 48 hours of rescue tocolysis improves neonatal outcome is unproven.

    OBJECTIVES: To evaluate the effectiveness of maintenance tocolytic therapy with oral nifedipine on the reduction of adverse neonatal outcomes and the prolongation of pregnancy by performing an individual patient data meta-analysis (IPDMA).

    SEARCH STRATEGY: We searched PubMed, Embase, and Cochrane databases for randomised controlled trials of maintenance tocolysis therapy with nifedipine in preterm labour.

    SELECTION CRITERIA: We selected trials including pregnant women between 24 and 36(6/7)  weeks of gestation (gestational age, GA) with imminent preterm labour who had not delivered after 48 hours of initial tocolysis, and compared maintenance nifedipine tocolysis with placebo/no treatment.

    DATA COLLECTION AND ANALYSIS: The primary outcome was perinatal mortality. Secondary outcome measures were intraventricular haemorrhage (IVH), necrotising enterocolitis (NEC), infant respiratory distress syndrome (IRDS), prolongation of pregnancy, GA at delivery, birthweight, neonatal intensive care unit admission, and number of days on ventilation support. Pre-specified subgroup analyses were performed.

    MAIN RESULTS: Six randomised controlled trials were included in this IPDMA, encompassing data from 787 patients (n = 390 for nifedipine; n = 397 for placebo/no treatment). There was no difference between the groups for the incidence of perinatal death (risk ratio, RR 1.36; 95% confidence interval, 95% CI 0.35-5.33), intraventricular haemorrhage (IVH) ≥ grade II (RR 0.65; 95% CI 0.16-2.67), necrotising enterocolitis (NEC) (RR 1.15; 95% CI 0.50-2.65), infant respiratory distress syndrome (IRDS) (RR 0.98; 95% CI 0.51-1.85), and prolongation of pregnancy (hazard ratio, HR 0.74; 95% CI 0.55-1.01).

    CONCLUSION: Maintenance tocolysis is not associated with improved perinatal outcome and is therefore not recommended for routine practice.

    TWEETABLE ABSTRACT: Nifedipine maintenance tocolysis is not associated with improved perinatal outcome or pregnancy prolongation.

    Matched MeSH terms: Infant, Newborn, Diseases/mortality; Infant, Newborn, Diseases/prevention & control
  12. Asha'ari ZA, Suhaimi Y, Fadzil A, Zihni M
    Malays J Med Sci, 2012 Oct;19(4):84-7.
    PMID: 23613654 MyJurnal
    Acquired subglottic cyst in infancy is almost always associated with episodes of early life intubation. Most cases typically presented late, usually days to months after extubation. We report a case of a subglottic cyst with different presentation than the norm. This case highlights that subglottic cyst can present acutely, and rapidly enlarging soon after the airway extubation. As the management of a large subglottic cyst can be challenging, a close observation for early diagnosis and intervention are recommended post extubation in the high-risk cases, such as in the premature infant.
    Matched MeSH terms: Infant, Newborn, Diseases
  13. Tai, Yong-Ting, Tong, Chin-Voon
    We report a case of occult primary spontaneous
    pneumothorax in a 30 years-old woman. She
    developed symptoms and signs that were suggestive of
    pneumothorax. However, chest radiograph failed to
    reveal pneumothorax. Therefore, we proceeded with
    computed tomography (CT) thorax which revealed
    significantly moderate right pneumothorax. The
    diagnostic approach and the management of this case
    are discussed.
    Matched MeSH terms: Infant, Newborn, Diseases
  14. Fong CY, Harvey AS
    Dev Med Child Neurol, 2014 Nov;56(11):1093-9.
    PMID: 24861161 DOI: 10.1111/dmcn.12496
    To evaluate the electroclinical features of epilepsy secondary to neonatal hypoglycaemia.
    Matched MeSH terms: Infant, Newborn, Diseases*
  15. Ullah A, Barman A, Haque J, Khanum M, Bari I
    Paediatr Perinat Epidemiol, 2009 Nov;23(6):542-7.
    PMID: 19840290 DOI: 10.1111/j.1365-3016.2009.01063.x
    It has been suggested that a birthweight limit of 2.5 kg should not be regarded as valid for all populations as the cut-off point of low-weight births because of demographic, genetic and environmental differences. Countries often choose alternative cut-off values for low birthweight for clinical purposes. Bangladesh also needs to choose a convenient cut-off value for low birthweight. A total of 770 live singleton full-term normal newborns were included in this study by stratified sampling; birthweight was measured using the Detecto-type baby weight machine. Newborns were followed up to the end of their first week of life. For data collection a pretested structured questionnaire and an Apgar Score estimating checklist were used. Chi-square test was applied to assess the association of different birthweight strata and neonatal health outcomes. Multiple logistic regression analyses were carried out to identify the independent effects of different levels of birthweight on early neonatal health. The neonates having birthweight < or = 2 kg had a significantly higher risk of early neonatal mortality and morbidity than the higher level birthweight group. Birth asphyxia was the commonest cause of early neonatal mortality and morbidity. Borderline birthweight (>2 to <2.5 kg) neonates experienced the same mortality and morbidity rates as the normal birthweight neonates during their early neonatal life. Birthweight < or = 2 kg may be one of the criteria for admission to a neonatal intensive care unit whereas more than 2 kg may not require admission unless otherwise necessary.
    Matched MeSH terms: Infant, Newborn, Diseases/mortality*
  16. Kuhan N, Abidin Z, Koh KH
    Med. J. Malaysia, 1981 Mar;36(1):37-8.
    PMID: 7321936
    Matched MeSH terms: Infant, Newborn, Diseases/therapy*
  17. Chen PC
    PMID: 1051832
    Matched MeSH terms: Infant, Newborn, Diseases/etiology*
  18. Sinniah D
    Med J Malaya, 1971 Mar;25(3):211-4.
    PMID: 4253249
    Matched MeSH terms: Infant, Newborn, Diseases/epidemiology*
  19. Chen ST, Edsall G, Peel MM, Sinnathuray TA
    Bull. World Health Organ., 1983;61(1):159-65.
    PMID: 6601539
    The relationship between the timing of maternal tetanus toxoid immunization and the presence of protective antitoxin in placental cord blood was investigated among women admitted to the obstetrical service of the University Hospital in Kuala Lumpur, Malaysia. The 1st dose was given between 13-39 weeks of gestation, with a median of 29 weeks. The 2nd dose was given an average of 4 weeks later. Protection was conferred on 80% or more of newborns whose mothers received their 1st tetanus toxoid injection 60 days or more before delivery. Protective levels were seen in all cord blood samples from infants whose mothers had received their 1st injection 90 days before delivery. Similarly,protective titers were found in 100% of cord blood samples when the 2nd maternal injection was give 60 days or more before delivery. There was no significant degree of protection when immunization was carried out less than 20 days before delivery. A single-dose schedule provided no protection when less than 70 days before delivery. Cord and maternal antiotoxin titers differed by no more than 1 2-fold dilution for almost all of the individual paired sera. A cord: maternal antitoxin ratio of 2 was more likely to occur with increasing time between the 2nd injection and delivery. Overall, these findings indicate that the 1st injection of a 2-dose maternal tetanus toxoid schedule should be given at least 60 days and preferably 90 days before delivery.
    Matched MeSH terms: Infant, Newborn, Diseases/prevention & control*
  20. Jamal F, Mohamed R, Zainal Z, Arshat H
    Med. J. Malaysia, 1979 Jun;33(4):349-51.
    PMID: 574917
    Matched MeSH terms: Infant, Newborn, Diseases/microbiology*
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