Displaying publications 1 - 20 of 285 in total

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  1. Ashoka Menon M, Saw Huat Seong
    Med J Malaysia, 1979 Mar;33(3):230-4.
    PMID: 522728
    Matched MeSH terms: Lung Neoplasms/diagnosis*
  2. Thirunanthini Manoharan, Jayanthi Arasan, Habshah Midi, Mohd Bakri Adam
    Sains Malaysiana, 2017;46:2529-2539.
    Left-truncated and censored survival data are commonly encountered in medical studies. However, traditional inferential methods that heavily rely on normality assumptions often fail when lifetimes of observations in a study are both truncated and censored. Thus, it is important to develop alternative inferential procedures that ease the assumptions of normality and unconventionally relies on the distribution of data in hand. In this research, a three parameter log-normal parametric survival model was extended to incorporate left-truncated and right censored medical data with covariates. Following that, bootstrap inferential procedures using non-parametric and parametric bootstrap samples were applied to the parameters of this model. The performance of the parameter estimates was assessed at various combinations of truncation and censoring levels via a simulation study. The recommended bootstrap intervals were applied to a lung cancer survival data.
    Matched MeSH terms: Lung Neoplasms
  3. Saw Huat Seong, Ashoka Menon M
    Med J Malaysia, 1979 Mar;33(3):235-42.
    PMID: 522729
    Matched MeSH terms: Lung Neoplasms/diagnosis*
  4. Liam CK, Lim KH, Wong MM
    Med J Malaysia, 2001 Dec;56(4):514-31; quiz 532.
    PMID: 12014776
    Matched MeSH terms: Lung Neoplasms/diagnosis*; Lung Neoplasms/therapy*
  5. Gooi BH, Premnath N, Manjit S
    Med J Malaysia, 2004 Mar;59(1):112-4.
    PMID: 15535346
    The management of pulmonary metastasis from breast carcinoma is challenging and often consists of palliation of symptoms. Surgical resection of pulmonary metastasis is considered inappropriate in view of the disseminated nature of the disease and limited life expectancy. It can however be a worthwhile option if imaging, including bone scans rule out metastatic disease in other part of the body. We report a patient with pulmonary metastasis from breast carcinoma who was successfully treated with pulmonary wedge resection of the metastatic lesion.
    Matched MeSH terms: Lung Neoplasms/radiography; Lung Neoplasms/secondary*; Lung Neoplasms/surgery*
  6. Pandit S, Choudhury S, Das SK, Nandi S
    Med J Malaysia, 2012 Oct;67(5):542-4.
    PMID: 23770881
    A 65 year old male smoker was diagnosed with squamous cell carcinoma of upper lobe of the right lung complicated with Horner's syndrome and gradually increasing leucocytosis. Alhough the inflammatory biomarker level in serum was low, there was no definite way to determine the cause of the leucocytosis (whether infection or hematologic paraneoplastic syndrome). After empirical antibiotic therapy, his fever subsided but the leucocytosis persisted. It was difficult for us to take a decision regarding the priority of the treatment of infection or the lung cancer. Only after the first cycle chemotherapy, did the leucocytosis rapidly drop down. Normal serum procalcitonin level and quick response to chemotherapy indicated that leucocytosis was a manifestation of paraneoplastic syndrome. Treating the underlying cancer is the first step.
    Matched MeSH terms: Lung Neoplasms*
  7. Sachithanandan A, Badmanaban B
    Med J Malaysia, 2012 Feb;67(1):3-6.
    PMID: 22582540 MyJurnal
    Matched MeSH terms: Lung Neoplasms/diagnosis*; Lung Neoplasms/epidemiology
  8. Liam CK, Looi LM, Pailoor J, Alhady SF
    Ann Acad Med Singap, 1989 Nov;18(6):713-6.
    PMID: 2624423
    Three cases of progressive dyspnoea in young female adults due to pulmonary lymphangitic carcinomatosis are reported. The underlying primary neoplasm was gastric carcinoma in all 3 cases. The diagnosis was not suspected in 2 patients because of their young age.
    Matched MeSH terms: Lung Neoplasms/complications; Lung Neoplasms/secondary*
  9. TOCK PC
    Med J Malaya, 1962 Mar;16:219-24.
    PMID: 13921481
    Matched MeSH terms: Lung Neoplasms*
  10. Manavalan AS
    Med J Malaya, 1969 Dec;24(2):124-7.
    PMID: 4244137
    Matched MeSH terms: Lung Neoplasms*
  11. Raaschou-Nielsen O, Beelen R, Wang M, Hoek G, Andersen ZJ, Hoffmann B, et al.
    Environ Int, 2016 Feb;87:66-73.
    PMID: 26641521 DOI: 10.1016/j.envint.2015.11.007
    Particulate matter (PM) air pollution is a human lung carcinogen; however, the components responsible have not been identified. We assessed the associations between PM components and lung cancer incidence.
    Matched MeSH terms: Lung Neoplasms
  12. Ardeshirzadeh B, Anaraki NA, Irani M, Rad LR, Shamshiri S
    Mater Sci Eng C Mater Biol Appl, 2015 Mar;48:384-90.
    PMID: 25579938 DOI: 10.1016/j.msec.2014.12.039
    Polyethylene oxide (PEO)/chitosan (CS)/graphene oxide (GO) electrospun nanofibrous scaffolds were successfully developed via electrospinning process for controlled release of doxorubicin (DOX). The SEM analysis of nanofibrous scaffolds with different contents of GO (0.1, 0.2, 0.5 and 0.7wt.%) indicated that the minimum diameter of nanofibers was found to be 85nm for PEO/CS/GO 0.5% nanofibers. The π-π stacking interaction between DOX and GO with fine pores of nanofibrous scaffolds exhibited higher drug loading (98%) and controlled release of the DOX loaded PEO/CS/GO nanofibers. The results of DOX release from nanofibrous scaffolds at pH5.3 and 7.4 indicated strong pH dependence. The hydrogen bonding interaction between GO and DOX could be unstable under acidic conditions which resulted in faster drug release rate in pH5.3. The cell viability results indicated that DOX loaded PEO/CS/GO/DOX nanofibrous scaffold could be used as an alternative source of DOX compared with free DOX to avoid the side effects of free DOX. Thus, the prepared nanofibrous scaffold offers as a novel formulation for treatment of lung cancer.
    Matched MeSH terms: Lung Neoplasms/drug therapy*; Lung Neoplasms/metabolism; Lung Neoplasms/pathology
  13. Othman N, Nagoor NH
    Biomed Res Int, 2014;2014:318030.
    PMID: 24999473 DOI: 10.1155/2014/318030
    Lung cancer remains to be one of the most common and serious types of cancer worldwide. While treatment is available, the survival rate of this cancer is still critically low due to late stage diagnosis and high frequency of drug resistance, thus highlighting the pressing need for a greater understanding of the molecular mechanisms involved in lung carcinogenesis. Studies in the past years have evidenced that microRNAs (miRNAs) are critical players in the regulation of various biological functions, including apoptosis, which is a process frequently evaded in cancer progression. Recently, miRNAs were demonstrated to possess proapoptotic or antiapoptotic abilities through the targeting of oncogenes or tumor suppressor genes. This review examines the involvement of miRNAs in the apoptotic process of lung cancer and will also touch on the promising evidence supporting the role of miRNAs in regulating sensitivity to anticancer treatment.
    Matched MeSH terms: Lung Neoplasms/drug therapy; Lung Neoplasms/genetics*; Lung Neoplasms/pathology
  14. Ng TH, How SH, Kuan YC, Fauzi AR
    Annals of thoracic medicine, 2012 Jan;7(1):12-5.
    PMID: 22347344 DOI: 10.4103/1817-1737.91556
    This study was carried out to determine the prevalence, patient's characteristic and reasons for defaulting follow-up and treatment among patients with lung cancer.
    Matched MeSH terms: Lung Neoplasms
  15. Rosliza G, Hairulfaizi H, Joanna OS, Zamrin DM, Ramzisham AR
    Med J Malaysia, 2010 Jun;65(2):146-7.
    PMID: 23756801
    We present a rare case of a multifocal sclerosing haemangioma of the lung in a 49-year-old lady. A left pneumonectomy with complete excision of the tumour seems to be the curative treatment. The recent literature on this unusual presentation is reviewed.
    Matched MeSH terms: Lung Neoplasms
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