MyMedR

Fulltext An inpatient study of psychiatric illnesses in later life

Nair V

Med J Malaysia, 1980 Sep;35(1):77-85.

This was a retrospective study of 177 patients above the age of 45 who were admitted to the Psychiatric Unit, University Hospital Petaling Jaya during the period October 1975 to October 1978. The available socio-demographic and clinical data from the case files were studied. The patients were divided into two groups - those with effective illnesses and those with non-affective illnesses. The differences in socio-demographic background and clinical symptomatology between the two groups and how the data compares with that in other studies was reported. The sick elderly person is an economic and psychological liagility to .his family and society. Absence of illness in the elderly not only fosters their continued independence but also improves the quality of their individual life. Though no definite correlations or conclusions could be arrived at, this study has sought to bring into awareness the necessity of delineating possible illness precipitating stress factors in the social and domestic environment of patients in later life.

Matched MeSH terms: Mental Disorders/etiology*

Fulltext Immediate impact of COVID-19 on mental health and its associated factors among healthcare workers: A global perspective across 31 countries

Htay MNN, Marzo RR, AlRifai A, Kamberi F, El-Abasiri RA, Nyamache JM, et al.

J Glob Health, 2020 Dec;10(2):020381.

PMID: 33214890 DOI: 10.7189/jogh.10.020381

Matched MeSH terms: Mental Disorders/etiology*

Some concepts of mental illness of the Murut of Sarawak

Schmidt KE

Int J Soc Psychiatry, 1967 1 1;14(1):24-31.

PMID: 5601657

Matched MeSH terms: Mental Disorders/etiology

Fulltext Effect of having a subsequent child on the mental health of women who lost a child in the 2008 Sichuan earthquake: a cross-sectional study

Xu Y, Herrman H, Bentley R, Tsutsumi A, Fisher J

Bull World Health Organ, 2014 May 1;92(5):348-55.

PMID: 24839324 DOI: 10.2471/BLT.13.124677

To assess whether having a subsequent child had an effect on the mental health of Chinese mothers who lost a child during an earthquake.

Matched MeSH terms: Mental Disorders/etiology*

Fulltext Psychomotor epilepsy with rare psychiatric manifestations

Mazumdar PK

Med J Malaysia, 1995 Mar;50(1):114-5.

PMID: 7752965

A rare case of complex partial seizure (psychomotor epilepsy) with varying shades of psychiatric manifestations is presented. The highlights are multiplicity of its manifestation in the same case, its interchanging pattern and the variable durations. This gray area of psychiatry and neurology is discussed with special reference to diagnosis and management.

Matched MeSH terms: Mental Disorders/etiology*

Fulltext The consultation of traditional healers by Malay patients

Salleh MR

Med J Malaysia, 1989 Mar;44(1):3-13.

PMID: 2626110

Sixty four percent (104 patients) of Malay patients attending the Psychiatric Clinic for the first time were interviewed. A similar number from the general Out-patients Department (O.P.D.) randomly chosen, served as the control group. Seventy six (73.1%) psychiatric patients had consulted a bomoh prior to their visit to the clinic as compared to 26 (25%) O.P.D. patients. The number of bomohs consulted was significantly higher among the psychiatric patients than the O.P.D. patients. The strength of social support, the availability of a bomoh and the belief of the patients, friends and/or relatives in the bomoh have been suggested as the main factors that influenced the Malay patients in seeking bomoh treatment. The belief that mental illness is due to supernatural causes is firmly held by bomohs who reinforce this notion in those who seek their advice. The importance of understanding the patient's cultural background in treating psychiatric patients is highlighted.
Study site: Psychiatric clinic, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia

Matched MeSH terms: Mental Disorders/etiology

Main puteri: an indigenous Kelantanese form of psychotherapy

Chen PCY

Int J Soc Psychiatry, 1979;25(3):167-75.

PMID: 500287 DOI: 10.1177/002076407902500302

The permainan puteri (usually abbreviated to main puteri) is an indigenous Kelantanese healing ceremony in which the bomoh (traditional medicine-man), the sick individual and other participants become spirit-medium through whom puteri (spirits) are able to enact a permainan ('play'). It has been successfully used as a psychotherapy for depression. The bomoh assisted by his minduk (master of spirits) and a troupe of musicians, is able to provide a conceptual framework around which the sick individual can organize his vague, mysterious and chaotic symptoms so that they become comprehensible and orderly. At the same time the bomoh is able to draw the sick individual out of his state of morbid self-absorption and heighten his feelings of self-worth. The involvement of his family, relatives and friends tends to enhance group solidarity and reintegrate the sick individual into his immediate social group.

Matched MeSH terms: Mental Disorders/etiology

Classification and concepts of causation of mental illness in a rural Malay community

Chen PCY

Int J Soc Psychiatry, 1970;16(3):205-15.

PMID: 4325131 DOI: 10.1177/002076407001600307

Matched MeSH terms: Mental Disorders/etiology*

Long-term civil conflict, migration, and the mental health of adults left behind in Thailand: a longitudinal study

Ford K, Jampaklay A, Chamratrithirong A

Int J Public Health, 2019 Nov;64(8):1193-1201.

PMID: 31489461 DOI: 10.1007/s00038-019-01297-y

OBJECTIVES: A long-term civil conflict has been occurring in the southernmost provinces of Thailand, and migration to Malaysia has been accelerated by this conflict. The objective of this work was to examine the influence of perceived effects of the unrest, migration of a household member, and children left behind on the reporting of psychiatric symptoms of working age adults.

METHODS: A first round of data collection was conducted in 2014 including interviews with a probability sample of 1102 households and individual interviews with 2058 males and females aged 18-59. In 2016, a second round of data collection was conducted. A fixed effects model was used in the analysis.

RESULTS: The perceived effect of the unrest on the household was associated with an increased reporting of psychiatric symptoms. Furthermore, the migration of a household member for work and the presence of children left behind were related to an increased reporting of psychiatric symptoms among adults, especially among females.

CONCLUSIONS: The unrest and its associated migration was related to an increased reporting of psychiatric symptoms among working age adults in the study population.

Matched MeSH terms: Mental Disorders/etiology

Parenting attitudes and dimensions as predictors of adolescent behavioural problems in the Indian context: A community-based study

Sekaran VC, Kamath VG, Ashok L, Kamath A, Hegde AP, Devaramane V

Asian J Psychiatr, 2020 Apr;50:101941.

PMID: 32070886 DOI: 10.1016/j.ajp.2020.101941

INTRODUCTION: Adolescent behavioural problems are a growing public health concern. The authors in this study investigated paternal and maternal reports of parenting attitudes and dimensions as predictors of adolescent behavioural problems in the Indian context.

MATERIALS AND METHODS: Using stratified sampling at the community level, 640 parents including 419 mothers and 221 fathers participated in the study. Tools included a socio-demographic pro-forma; Parental attitude inventory (PAI) to assess parenting attitudes, Parent Global Report of the Alabama Parenting Questionnaire (APQ) to assess current parenting dimensions, and the parent version of the Strengths and Difficulties Questionnaire (SDQ) to assess behavioural problems among adolescents. We examined the prevalence and predictors of total difficulties, externalizing and internalizing behavioural problems among adolescents from paternal and maternal reports.

RESULTS: Paternal and maternal reports of total difficulties (11.3 %, 13.6 %), externalizing (2.3 %, 1.9 %) and internalizing behaviours (8.6 %, 7.4 %) among adolescents are reported. Predictors of abnormal behaviours per paternal reports included lower social class and poor paternal control. Being a male adolescent increased the odds of total difficulties and externalizing problems. Favourable maternal attitude, good maternal warmth and control predicted the reduced likelihood of total difficulties and externalizing behaviours per maternal reports. Paternal control and maternal warmth and control were found to reduce the likelihood of internalizing behaviours among adolescents.

CONCLUSION: Maternal attitude, paternal control and maternal warmth and control dimensions emerged as significant predictors of total difficulties, externalizing and internalizing behavioural problems among adolescents.

Matched MeSH terms: Mental Disorders/etiology

Fulltext Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Network and Pathway Analysis Subgroup of Psychiatric Genomics Consortium

Nat Neurosci, 2015 Feb;18(2):199-209.

PMID: 25599223 DOI: 10.1038/nn.3922

Genome-wide association studies (GWAS) of psychiatric disorders have identified multiple genetic associations with such disorders, but better methods are needed to derive the underlying biological mechanisms that these signals indicate. We sought to identify biological pathways in GWAS data from over 60,000 participants from the Psychiatric Genomics Consortium. We developed an analysis framework to rank pathways that requires only summary statistics. We combined this score across disorders to find common pathways across three adult psychiatric disorders: schizophrenia, major depression and bipolar disorder. Histone methylation processes showed the strongest association, and we also found statistically significant evidence for associations with multiple immune and neuronal signaling pathways and with the postsynaptic density. Our study indicates that risk variants for psychiatric disorders aggregate in particular biological pathways and that these pathways are frequently shared between disorders. Our results confirm known mechanisms and suggest several novel insights into the etiology of psychiatric disorders.

Matched MeSH terms: Mental Disorders/etiology

Latah: the symbolism of a putative mental disorder

Kenny MG

Cult Med Psychiatry, 1978 Sep;2(3):209-31.

PMID: 710172

This paper examines the symbolic properties and cultural relevance of latah, a behavioral state noted in Malay and Indonesia since the 19th Century. Most interpretations of latah have been psychological, latah being perceived as a 'mental disorder.' In the following, it is concluded that latah is intimately related to other aspects of Malayo-Indonesian culture and that it is a well-known cultural pattern and not a mental disorder as such, though it may occur among persons, largely women, in a socially and psychologically marginal situation. Latah is a symbolic representation of marginality, and it is as appropriate to certain mythological and religious figures to the socially marginal.

Matched MeSH terms: Mental Disorders/etiology

Paternal age and common mental disorders

Krishnaswamy S, Subramaniam K, Indran H, Ramachandran P, Indran T, Indran R, et al.

World J. Biol. Psychiatry, 2009;10(4 Pt 2):518-23.

PMID: 19191074 DOI: 10.1080/15622970802653691

There is evidence in the literature that there are associations between advancing paternal age and psychosis or more specifically schizophrenia, but not enough to support a strong link between advancing paternal age and common mental disorders.

Matched MeSH terms: Mental Disorders/etiology*

Effect of treating lower urinary tract symptoms on anxiety, depression and psychiatric morbidity: a one-year study

Quek KF, Razack AH, Chua CB, Low WY, Loh CS

Int J Urol, 2004 Oct;11(10):848-55.

PMID: 15479289

The present study aimed to evaluate the effects of treating lower urinary tract symptoms (LUTS) on anxiety, depression and psychiatric morbidity following one year of follow-up.

Matched MeSH terms: Mental Disorders/etiology*

Fulltext Psychiatric disorder in Malaysians with systemic lupus erythematosus

Chin CN, Cheong I, Kong N

Lupus, 1993 Oct;2(5):329-32.

PMID: 8305928 DOI: 10.1177/096120339300200510

All 79 patients who attended a University Systemic Lupus Erythematosus (SLE) Clinic over a 6 month period were assessed using the Clinical Interview Schedule for psychiatric disorder. Using the ICD-9 Classification, 40 were found to have psychiatric disorder, 26 having depressive neurosis, six anxiety neurosis, five endogenous depression and three dementia. The group with psychiatric disorder had significantly poor family support as well as lack of a confidant compared to the group without psychiatric disorder (P < 0.01). There was no difference between the group with psychiatric disorder and those without psychiatric disorder in terms of age, duration of illness, ethnicity and severity of SLE. Psychiatric disorder is common affecting more than half the subjects and depression was the most frequent diagnosis.
Study site: SLE clinics, Pusat Perubatan Universiti Kebangsaan Malaysia (PPUKM), Kuala Lumpur, Malaysia

Matched MeSH terms: Mental Disorders/etiology*

Population genetic variation of SLC6A4 gene, associated with neurophysiological development

Hande SH, Krishna SM, Sahote KK, Dev N, Erl TP, Ramakrishna K, et al.

J Genet, 2021;100.

PMID: 33764333

The serotonin transporter 5-HTT is encoded by a single gene SLC6A4. Polymorphisms in SLC6A4 has been associated with a wide variety of neurological and psychiatric disorders including increased risk of posttraumatic stress disorder, higher likelihood for depression, obsessive-compulsive disorder (OCD), increased hostility and criminal behaviour. Genes associated with complex diseases often exhibit strong signatures of purifying selection compared to others. Further, discernible population specific variation in the signature of natural selection have been observed for several complex disease-related genes. In this project we aimed to investigate the population genetic variation of the serotonin transporter gene (SLC6A4), focussing on the single nucleotide polymorphisms (SNPs). To this end, we employed 2504 individuals around the globe available in 1000 Genome project Phase III data and classified them into five ethnic groups: Americans (AMR), Europeans (EUR), Africans (AFR), East Asians (EAS) and South Asians (SAS). Principal component analysis (PCA) performed on all annotated SNPs of SLC6A4 depicted clear clustering between Africans and the rest of the world along PC1, and East Asians and other non-African populations along PC2. Further, these SNPs were found to be under strong selection pressure especially among East Asian populations with significantly high positive cross-population extended haplotype homozygosity scores compared to Africans, indicating that SLC6A4 has likely undergone a strong selective sweep among the East Asians in the recent past. Our study can potentially explain the association between polymorphisms in SLC6A4, and major depression and suicidal tendencies among people of East Asian ancestry and the absence of such associations among people of European ancestry.

Matched MeSH terms: Mental Disorders/etiology

The psychiatric aspects of epilepsy

Teoh JI

Med J Malaysia, 1973 Sep;28(1):8-15.

PMID: 4273788

Matched MeSH terms: Mental Disorders/etiology*

Psychiatric sequelae to a civil disturbance

Tan ES, Simons RC

Br J Psychiatry, 1973 Jan;122(566):57-63.

PMID: 4509384

Matched MeSH terms: Mental Disorders/etiology*

Fulltext The prevalence of stress, anxiety and depression within front-line healthcare workers caring for COVID-19 patients: a systematic review and meta-regression

Salari N, Khazaie H, Hosseinian-Far A, Khaledi-Paveh B, Kazeminia M, Mohammadi M, et al.

Hum Resour Health, 2020 12 17;18(1):100.

PMID: 33334335 DOI: 10.1186/s12960-020-00544-1

BACKGROUND: Stress, anxiety, and depression are some of the most important research and practice challenges for psychologists, psychiatrists, and behavioral scientists. Due to the importance of issue and the lack of general statistics on these disorders among the Hospital staff treating the COVID-19 patients, this study aims to systematically review and determine the prevalence of stress, anxiety and depression within front-line healthcare workers caring for COVID-19 patients.

METHODS: In this research work, the systematic review, meta-analysis and meta-regression approaches are used to approximate the prevalence of stress, anxiety and depression within front-line healthcare workers caring for COVID-19 patients. The keywords of prevalence, anxiety, stress, depression, psychopathy, mental illness, mental disorder, doctor, physician, nurse, hospital staff, 2019-nCoV, COVID-19, SARS-CoV-2 and Coronaviruses were used for searching the SID, MagIran, IranMedex, IranDoc, ScienceDirect, Embase, Scopus, PubMed, Web of Science (ISI) and Google Scholar databases. The search process was conducted in December 2019 to June 2020. In order to amalgamate and analyze the reported results within the collected studies, the random effects model is used. The heterogeneity of the studies is assessed using the I2 index. Lastly, the data analysis is performed within the Comprehensive Meta-Analysis software.

RESULTS: Of the 29 studies with a total sample size of 22,380, 21 papers have reported the prevalence of depression, 23 have reported the prevalence of anxiety, and 9 studies have reported the prevalence of stress. The prevalence of depression is 24.3% (18% CI 18.2-31.6%), the prevalence of anxiety is 25.8% (95% CI 20.5-31.9%), and the prevalence of stress is 45% (95% CI 24.3-67.5%) among the hospitals' Hospital staff caring for the COVID-19 patients. According to the results of meta-regression analysis, with increasing the sample size, the prevalence of depression and anxiety decreased, and this was statistically significant (P mental disorders in the Hospital staff.

Matched MeSH terms: Mental Disorders/etiology

Is survival enough for quality of life in Sagliker Syndrome-uglifying human face appearances in chronic kidney disease?

Sagliker Y, Acharya V, Golea O, Sabry A, Bali M, Eyupoglu K, et al.

J Nephrol, 2008 Mar-Apr;21 Suppl 13:S134-8.

PMID: 18446747

It is known that secondary hyperparathyroidism (SH) and particularly skeletal changes is a severe condition in chronic kidney disease (CKD). Sagliker syndrome (SS) is a very prominent feature in CKD including uglifying human face appearances, short stature, extremely severe maxillary and mandibulary changes, soft tissues in the mouth, teeth-dental abnormalities, finger tip changes and severe psychological problems.

Matched MeSH terms: Mental Disorders/etiology*

Displaying publications 1 - 20 of 24 in total