Displaying publications 1 - 20 of 69 in total

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  1. Nadarajah A
    Family Practitioner, 1978;3:8-12.
    Matched MeSH terms: Coma; Diabetic Coma
  2. Kan CH, Saffari M, Khoo TH
    Malays J Med Sci, 2009 Oct;16(4):25-33.
    PMID: 22135509 MyJurnal
    Traumatic Brain Injury (TBI) in children has been poorly studied, and the literature is limited. We evaluated 146 children with severe TBI (coma score less than 8) in an attempt to establish the prognostic factors of severe TBI in children.
    Matched MeSH terms: Coma; Glasgow Coma Scale
  3. Tan BY, Cheah JS, Tan SK, Chew BK
    Med J Malaya, 1970 Jun;24(4):308-10.
    PMID: 4248355
    Matched MeSH terms: Diabetic Coma*
  4. von Tunzelmann EW
    Matched MeSH terms: Coma
  5. BROWNE J
    Med J Malaya, 1954 Dec;9(2):99-114.
    PMID: 14355274
    Matched MeSH terms: Insulin Coma*
  6. Liong CC, Rahmat K, Mah JS, Lim SY, Tan AH
    Can J Neurol Sci, 2016 Sep;43(5):719-20.
    PMID: 27670213 DOI: 10.1017/cjn.2016.269
    Matched MeSH terms: Glasgow Coma Scale
  7. Seed, H.F., Thong, K.S., Siti-Nor Aizah, A.
    MyJurnal
    Although disturbance of consciousness in delirium patients have been well
    established, but sudden drop of Glasgow Coma Scale (GCS) level to three is
    frightening and mysterious. We are reporting a case of a delirious elderly
    man with multiple medical illnesses presented with acute precipitous
    decrement of GCS with pin point pupils bilaterally after given a course of
    benzodiazepines and regained full consciousness spontaneously 32 hours
    later. We discussed the use of deliriogenic medications in the context of
    delirious elderly gentleman with multiple medical illnesses. We also looked
    into the possible differentials of sudden drop of conscious level with bilateral
    pin point pupils.
    Matched MeSH terms: Glasgow Coma Scale
  8. Lim TO, Ngah BC
    Med. J. Malaysia, 1990 Sep;45(3):260-2.
    PMID: 2152091
    We report a patient with hyperosmolar non-ketotic hyperglycaemia who presented with chorea and septic arthritis on his knee. The chorea resolved completely and quickly with correction of the metabolic disturbance, only to return just as quickly when his metabolic disturbance subsequently deteriorated as a result of overwhelming septicaemia, suggesting coexisting cerebral ischaemia, although the basis of focal neurological sign in non-ketotic hyperglycaemia remains controversial.
    Matched MeSH terms: Hyperglycemic Hyperosmolar Nonketotic Coma/complications; Hyperglycemic Hyperosmolar Nonketotic Coma/diagnosis*
  9. Arumugasamy N, Siqueira EB
    Med J Malaya, 1970 Dec;25(2):155-60.
    PMID: 4251137
    Matched MeSH terms: Diabetic Coma/complications; Diabetic Coma/etiology*
  10. Chan YF
    Med J Malaya, 1972 Mar;26(3):211-4.
    PMID: 5031019
    Matched MeSH terms: Diabetic Coma/drug therapy; Diabetic Coma/etiology*
  11. Sofiah A, Hussain IH
    Ann Trop Paediatr, 1997 Dec;17(4):327-31.
    PMID: 9578792
    All post-neonatal children with acute non-traumatic coma admitted over an 8-month period were analysed and followed up for 18-24 months to determine the aetiology and outcome of their coma. One hundred and sixteen children, 72 boys and 44 girls, were recruited. Half the children were under 1 year of age and only 16 (14%) were more than 6 years of age. Eighty cases (69%) were due to infection, 15 (13%) to toxic metabolic causes, six (5%) to hypoxic ischaemic insults, four (3.5%) had intracranial haemorrhage, nine (7.8%) were due to miscellaneous causes and in two (1.7%) the cause was unknown. Seven cases were lost to follow-up. Of the remainder, 39 (35.7%) died, 32 (29.3%) developed permanent neurological deficit, and 38 (35%) were discharged well. The outcome was worst in the infectious group. Age of onset and sex did not significantly affect outcome. Our findings are similar to experience in Japan, where infection accounts for 74% of non-traumatic coma, but differ considerably from Western data on childhood coma where only a third of cases are due to infection.
    Matched MeSH terms: Coma/etiology*; Coma/microbiology
  12. Wan Hassan WM, Najid NM, Muslim HS, Izaini Ghani AR
    Asian J Neurosurg, 2015 3 15;10(1):59.
    PMID: 25767595 DOI: 10.4103/1793-5482.151528
    Barbiturate coma therapy (BCT) is a choice treatment for refractory intracranial hypertension after all surgical or medical managements have failed to control the intracranial pressure (ICP). It helps to reduce cerebral blood flow, cerebral metabolic rate of oxygen consumption and ICP. However, this therapy can also cause many complications. One of the underreported, but life-threatening complications is refractory hypokalemia, which can lead to subsequent rebound hyperkalemia after sudden cessation. We report our experience of managing unusual complication of refractory hypokalemia during BCT with thiopentone in postdecompressive craniectomy patient.
    Matched MeSH terms: Coma
  13. Idris Z, Zenian MS, Muzaimi M, Hamid WZ
    Asian J Neurosurg, 2014 Jul-Sep;9(3):115-23.
    PMID: 25685201 DOI: 10.4103/1793-5482.142690
    Induced hypothermia for treatment of traumatic brain injury is controversial. Since many pathways involved in the pathophysiology of secondary brain injury are temperature dependent, regional brain hypothermia is thought capable to mitigate those processes. The objectives of this study are to assess the therapeutic effects and complications of regional brain cooling in severe head injury with Glasgow coma scale (GCS) 6-7.
    Matched MeSH terms: Glasgow Coma Scale
  14. Liew BS, Zainab K, Cecilia A, Zarina Y, Clement T
    Malays Fam Physician, 2017;12(1):22-25.
    PMID: 28503270
    Head injury is common and preventable. Assessment of the head injury patient includes airway, cervical spine protection, breathing, circulation, haemorrhage control and the Glasgow Coma Scale. Hypotension, hypoxia, hypocarbia and hypercarbia should be avoided by continuous monitoring of vital signs and hourly head chart to prevent secondary brain injury. This paper aims to assist primary healthcare providers to select the appropriate patient for transfer and imaging for further management of head injury.
    Matched MeSH terms: Glasgow Coma Scale
  15. Visvanathan R
    Aust N Z J Surg, 1994 Aug;64(8):527-9.
    PMID: 8048888 DOI: 10.1111/j.1445-2197.1994.tb02278.x
    Sixty-nine severely head-injured patients treated by general surgeons over a 28 month period with admission Glasgow Coma Scale motor scores of 3 to 8 were reviewed retrospectively. Fifty-one patients were comatose on admission with periods from injury to admission exceeding 4 h in 34 patients who were referred from peripheral hospitals. Forty patients with acute intracranial bleeding underwent emergency decompressive surgery with 13 good recoveries and 18 deaths; good recoveries were observed in 11 of 20 patients with extradural haemorrhages, one out of eight patients with subdural haemorrhages, and one of 12 patients with intracerebral and/or combined haemorrhages. Twenty-nine patients with no evidence of acute mass lesions were treated medically with sedation, mechanical ventilation and mannitol infusion for cerebral decompression with seven good recoveries and 16 deaths. There were 15 good outcomes in 40 patients with admission motor scores of 6, 7 or 8 and five good outcomes in 29 patients with scores of 3, 4 or 5. A good outcome of 29% in the study may be improved by (i) better neurosurgical training of surgical and nursing staff; (ii) provision of technologically advanced diagnostic and treatment modalities; (iii) an efficient referral system; and (iv) provision of effective long-term rehabilitation.
    Matched MeSH terms: Coma/radiography; Coma/surgery; Glasgow Coma Scale
  16. Law HL, Tan S, Sedi R
    Malays J Med Sci, 2011 Jul;18(3):71-4.
    PMID: 22135604
    We report a case of Wernicke's encephalopathy in a patient with nasopharyngeal carcinoma with a 3-month history of poor oral intake related to nausea and vomiting due to chemotherapy. The patient later developed deep coma while receiving in-patient therapy. Magnetic resonance imaging of the brain revealed typical findings of Wernicke's encephalopathy. The patient was treated with thiamine injections, which resulted in subsequent partial recovery of neurological function. This paper stresses the importance of magnetic resonance imaging for prompt diagnosis of Wernicke's encephalopathy.
    Matched MeSH terms: Coma
  17. Tat YB, Hassan WMNW, Chuen TY, Ghani ARI
    Malays J Med Sci, 2017 Mar;24(2):100-105.
    PMID: 28894410 MyJurnal DOI: 10.21315/mjms2017.24.2.13
    Barbiturate coma therapy (BCT) is a treatment option that is used for refractory intracranial hypertension after all other options have been exhausted. Although BCT is a brain protection treatment, it also has several side effects such as hypotension, hepatic dysfunction, renal dysfunction, respiratory complications and electrolyte imbalances. One less concerning but potentially life-threatening complication of BCT is dyskalaemia. This complication could present as severe refractory hypokalaemia during the therapy with subsequent rebound hyperkalaemia after cessation of the therapy. Judicious potassium replacement during severe refractory hypokalaemia and gradual cessation of the therapy to prevent rebound hyperkalaemia are recommended strategies to deal with this complication, based on previous case series and reports. In this case report, we show that these strategies were applicable in improving severe hypokalaemia and preventing sudden, life-threatening rebound hyperkalaemia. However, even with use of these strategies, BCT patients could still present with mild, asymptomatic hyperkalaemia.
    Matched MeSH terms: Coma
  18. Sidek MSM, Siregar JA, Ghani ARI, Idris Z
    Malays J Med Sci, 2018 Mar;25(2):95-104.
    PMID: 30918459 DOI: 10.21315/mjms2018.25.2.10
    Background: With teleneurosurgery, more patients with head injury are managed in the primary hospital under the care of general surgical unit. Growing concerns regarding the safety and outcome of these patients are valid and need to be addressed.

    Method: This study is to evaluate the outcome of patients with mild head injury which were managed in non-neurosurgical centres with the help of teleneurosurgery. The study recruits samples from five primary hospitals utilising teleneurosurgery for neurosurgical consultations in managing mild head injury cases in Johor state. Two main outcomes were noted; favourable and unfavourable, with a follow up review of the Glasgow Outcome Scale (GOS) at 3 and 6 months.

    Results: Total of 359 samples were recruited with a total of 11 (3.06%) patients have an unfavourable. no significant difference in GOS at 3 and 6 months for patient in the unfavourable group (P = 0.368).

    Conclusion: In this study we have found no significant factors affecting the outcome of mild head injury patients managed in non-neurosurgical centres in Johor state using the help of teleneurosurgery.

    Matched MeSH terms: Glasgow Coma Scale
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