Displaying publications 1 - 20 of 21 in total

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  1. Ramachandran CP, Ramalingam S, Chelvam MP
    Med J Malaya, 1966 Jun;20(4):338-9.
    PMID: 4224564
    Matched MeSH terms: Filarioidea/isolation & purification*
  2. Sandosham AA, Sivanandam S, Fong YL, Omar I
    Med J Malaya, 1966 Jun;20(4):340.
    PMID: 4224353
    Matched MeSH terms: Filarioidea/isolation & purification*
  3. Sandosham AA, Sivanandam S
    Med J Malaya, 1966 Jun;20(4):339-40.
    PMID: 4224352
    Matched MeSH terms: Filarioidea/isolation & purification*
  4. Ramachandran CP, Loke YW, Hagendrom C
    Med J Malaya, 1966 Jun;20(4):344-7.
    PMID: 4224357
    Matched MeSH terms: Filarioidea/isolation & purification*
  5. Sivanandam S, Dondero TJ
    PMID: 5112357
    Matched MeSH terms: Filarioidea/isolation & purification
  6. Dissanaike AS, Hock QC, Min TS
    Am J Trop Med Hyg, 1974 Nov;23(6):1023-6.
    PMID: 4429177
    Matched MeSH terms: Filarioidea/isolation & purification*
  7. Strauss JM, Sivanandam S
    Med J Malaya, 1966 Jun;20(4):336.
    PMID: 4224351
    Matched MeSH terms: Filarioidea/isolation & purification
  8. Schmidt GD, Kuntz RE
    Parasitology, 1970 Apr;60(2):313-26.
    PMID: 5427102
    Matched MeSH terms: Filarioidea/isolation & purification
  9. Ho CC, Ideris N
    Infection, 2013 Aug;41(4):893-6.
    PMID: 23471824 DOI: 10.1007/s15010-013-0443-x
    Parasite infestation of the testicular tunica and spermatic cord by filariae are rarely reported and may present with few clinical signs, depending upon the stage. Occasionally, it may mimic a testicular tumor. We present a case of a 29-year-old man who presented with left testicular swelling and discomfort for 4 months. Clinical examination and imaging suggested an intrascrotal cystic lesion with a normal left testis. However, the intraoperative findings revealed a tumor-like mass; hence, a left orchidectomy was performed. However, histopathology reported a diagnosis of a cystic testicular tunica and spermatic cord with parasite infection. Here, we review the literature of scrotal and testicular parasite disease and discuss the course of the appropriate management involved.
    Matched MeSH terms: Filarioidea/isolation & purification*
  10. Dondero TJ, Sivanandam S
    Med J Malaysia, 1973 Jun;27(4):306-9.
    PMID: 4270791
    Matched MeSH terms: Filarioidea/isolation & purification*
  11. Barclay R
    Ann Trop Med Parasitol, 1969 Dec;63(4):473-88.
    PMID: 4393668
    Matched MeSH terms: Filarioidea/isolation & purification
  12. Yap LF, Ramachandran CP, Balasingam E
    Med J Malaya, 1968 Dec;23(2):118-22.
    PMID: 4240821
    Matched MeSH terms: Filarioidea/isolation & purification*
  13. Fadzil M, Cheah TS, Subramaniam P
    Vet Rec, 1973 Mar 24;49(12):316-8.
    PMID: 4716635
    Matched MeSH terms: Filarioidea/isolation & purification
  14. Rubis P, Chang MS, Nagum AJ, Jau JL
    PMID: 6114566
    A total of 82 persons have been found to be positive for microfilaria a sub-periodic Brugia malayi out of 1,613 examined in seven villages in Serian District. This represents an average microfilaria infection rate of 5.1% with a range of zero to 10.7%. It is found that males are more predominantly affected than females with a ratio of 3:1. It is also confirmed that Mansonia dives and M. bonneae are possible vectors for the transmission of the disease although Anopheles species cannot be ruled out owing to the small number of specimens examined. The study is confined to areas where indoor DDT spraying has been done since 1960 and only in two of the areas it has been terminated in 1966. Yet to be published data shows higher filaria infection rate than any of these villages.
    Matched MeSH terms: Filarioidea/isolation & purification*
  15. Lim PK
    PMID: 7973946
    Accurate diagnosis of human filarial infections still remains a problem for clinicians and co-ordinators of filariasis control programs. Diagnosis of filariasis is based on parasitological, histopathological, clinical and immunological approaches. No significant advances have been made for the first three approaches although some refinements in their use and interpretation of results have occurred. For the immunological approach, intradermal tests and antibody detection assays using crude parasite extracts generally lack specificity and/or sensitivity to discriminate between past and present filarial infections in humans. Antigen detection assays would therefore provide a more accurate indication of active filarial infections. Several monoclonal antibodies to various stages of lymphatic filarial parasites have been developed and appear potentially useful for filarial antigen detection.
    Matched MeSH terms: Filarioidea/isolation & purification*
  16. Liat LB, Wah MJ, Singh M, Ho BC, Hian YE
    PMID: 1166352
    Seven of the 18 species of lowland forest terrestrial and semi-arboreal murids were found naturally infected with Breinlia booliati. Of these, two species, Rattus sabanus and R. cremoriventer, were found to be the most preferred hosts. None of the murids from the highland, field or human-inhabited areas was infected. This could have been due more to the greater scarcity of the vectors in these habitats than to the susceptibility of the hosts. The absence of this parasite in the squirrels examined may be attributed either to host specificity or to the normal activity cycles or vertical stratification of the vectors, separating them in space and/or time from the squirrels. The pattern of dispersion of the parasite is influenced by the wide distribution of suitable hosts, and the hypothesis that the parasite is of forest origin is discussed.
    Matched MeSH terms: Filarioidea/isolation & purification
  17. Uni S, Bain O, Fujita H, Matsubayashi M, Fukuda M, Takaoka H
    Parasite, 2013;20:1.
    PMID: 23340227 DOI: 10.1051/parasite/2012001
    Hard ticks taken from the Japanese serow, Capricornis crispus, in Yamagata Prefecture, Honshu, harboured infective larvae of onchocercid filariae after incubation from the 22nd to the 158th day. Haemaphysalis flava and H. japonica contained one to eight filarial larvae; females, males and a nymph of the ticks were infected. The 44 infective larvae recovered were 612-1,370 μm long, and 11 of them, 930-1,340 μm long, were studied in detail. The larvae possessed the morphologic characteristics of the larvae of the genus Cercopithifilaria, namely an oesophagus with a posterior glandular part, no buccal capsule and a long tail with three terminal lappets. Five types (A to E) of infective larvae were identified based on the morphologic characteristics. While to date five species of Cercopithifilaria have been described from the Japanese serow, a specific identification of the larvae found in this study was generally not possible. Only type E larvae could be tentatively assigned to Cercopithifilaria tumidicervicata, as they had a cervical swelling similar to that of the adults of this species. A key for the identification of the five larval types is presented. The study presents circumstantial evidences indicating that H. flava and H. japonica may transmit Cercopithifilaria spp. to Japanese serows. It also suggests the possibility that such filarial larvae will be found in hard ticks anywhere, because Cercopithifilaria is distributed worldwide, though this genus generally goes unnoticed, as its microfilariae occur in the skin, not in the blood, of host animals.
    Matched MeSH terms: Filarioidea/isolation & purification*
  18. Uni S, Mat Udin AS, Agatsuma T, Saijuntha W, Junker K, Ramli R, et al.
    Parasit Vectors, 2017 Apr 20;10(1):194.
    PMID: 28427478 DOI: 10.1186/s13071-017-2105-9
    BACKGROUND: The filarial nematodes Wuchereria bancrofti (Cobbold, 1877), Brugia malayi (Brug, 1927) and B. timori Partono, Purnomo, Dennis, Atmosoedjono, Oemijati & Cross, 1977 cause lymphatic diseases in humans in the tropics, while B. pahangi (Buckley & Edeson, 1956) infects carnivores and causes zoonotic diseases in humans in Malaysia. Wuchereria bancrofti, W. kalimantani Palmieri, Pulnomo, Dennis & Marwoto, 1980 and six out of ten Brugia spp. have been described from Australia, Southeast Asia, Sri Lanka and India. However, the origin and evolution of the species in the Wuchereria-Brugia clade remain unclear. While investigating the diversity of filarial parasites in Malaysia, we discovered an undescribed species in the common treeshrew Tupaia glis Diard & Duvaucel (Mammalia: Scandentia).

    METHODS: We examined 81 common treeshrews from 14 areas in nine states and the Federal Territory of Peninsular Malaysia for filarial parasites. Once any filariae that were found had been isolated, we examined their morphological characteristics and determined the partial sequences of their mitochondrial cytochrome c oxidase subunit 1 (cox1) and 12S rRNA genes. Polymerase chain reaction (PCR) products of the internal transcribed spacer 1 (ITS1) region were then cloned into the pGEM-T vector, and the recombinant plasmids were used as templates for sequencing.

    RESULTS: Malayfilaria sofiani Uni, Mat Udin & Takaoka, n. g., n. sp. is described based on the morphological characteristics of adults and microfilariae found in common treeshrews from Jeram Pasu, Kelantan, Malaysia. The Kimura 2-parameter distance between the cox1 gene sequences of the new species and W. bancrofti was 11.8%. Based on the three gene sequences, the new species forms a monophyletic clade with W. bancrofti and Brugia spp. The adult parasites were found in tissues surrounding the lymph nodes of the neck of common treeshrews.

    CONCLUSIONS: The newly described species appears most closely related to Wuchereria spp. and Brugia spp., but differs from these in several morphological characteristics. Molecular analyses based on the cox1 and 12S rRNA genes and the ITS1 region indicated that this species differs from both W. bancrofti and Brugia spp. at the genus level. We thus propose a new genus, Malayfilaria, along with the new species M. sofiani.

    Matched MeSH terms: Filarioidea/isolation & purification
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