Displaying all 14 publications

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  1. Ng CY, Lee SL, Foo SL
    Med J Malaysia, 2017 08;72(4):244-245.
    PMID: 28889137 MyJurnal
    Abdominal pain is one of the common presentations in severe dengue infection. We report a rare case of perforated gastric ulcer in a young man diagnosed with severe dengue infection and the challenges we faced in managing this patient. Perforated gastric ulcer need to be considered if there are signs of peritonitis and persistent abdominal pain that does not conform to the natural history of dengue. Proper imaging and early surgical intervention in perforated gastric ulcer is vital in preventing further complication and reducing the risk of mortality.
    Matched MeSH terms: Peptic Ulcer Perforation/etiology*; Peptic Ulcer Perforation/surgery; Peptic Ulcer Perforation/virology
  2. Loh KY, Kew ST
    Malays Fam Physician, 2008;3(2):109-10.
    PMID: 25606131
    Matched MeSH terms: Peptic Ulcer Perforation
  3. Said MY
    Med J Malaysia, 1982 Sep;37(3):261-4.
    PMID: 7177009
    In a 3 year period 73 cases of perforated peptic ulcers were treated by simple closure. The overall mortality of 3.77 percent is acceptable when compared with other reports. There was a marked male preponderance (11 males: female 1). Biopsy results confirmed the operatiue findings that perforations were seven times more common in gastric peptic ulcers than duodenal ones. The disease affected young adults, the middle aged and elderly, the peak incidence occurring between the fifth and seventh decades oflife. Simple closure was an effective surgical procedure for our group of patients.
    Matched MeSH terms: Peptic Ulcer Perforation/surgery*
  4. Tan SL
    Med J Malaysia, 1980 Dec;35(2):162-3.
    PMID: 7266411
    A 103 year old patient was admitted with pain in the right iliac fossa. There was no response to conservative treatment. Subsequent laparatomy showed the presence of a perforated ulcer in the pyloric region. The condition improved gradually after the surgical management.
    Matched MeSH terms: Peptic Ulcer Perforation/diagnosis*
  5. Michael A, Jasjit SN, Prabhu R
    Med J Malaysia, 2015 Dec;70(6):365-6.
    PMID: 26988213 MyJurnal
    Fulminant necrotising amoebic colitis is a complication of untreated amoebiasis. This is seen in mainly low-income countries. It has a high mortality rate and is difficult to diagnose. We present an extremely rare case of fulminant necrotising amoebic colitis that caused diagnostic confusion in mimicking an acute abdomen, presumably caused by a perforated duodenal ulcer.
    Matched MeSH terms: Peptic Ulcer Perforation
  6. Black K
    Matched MeSH terms: Peptic Ulcer Perforation
  7. Kugan V, Mahadevan DT, Kandasami P
    Med J Malaysia, 2016 02;71(1):12-6.
    PMID: 27130737
    BACKGROUND: Perforated peptic ulcers (PPU) present as serious surgical emergencies that carry high mortality and morbidity. Foreigners with PPU are also managed in our hospital setting. Their inclusion significantly alters the trend and pattern of PPU seen in Malaysia.

    AIM: To compare per-operative and post-operative features and outcomes of perforated peptic ulcers between Malaysians and foreigners.

    MATERIAL AND METHODS: This was an analytical crosssectional study. All patients who underwent repair of perforated peptic ulcer disease during a 6-year period were included. 50 consecutive patients' records with perforated peptic ulcer were analysed. Data were collected from operation theatre database and hospital medical records. Chi square and t test were performed using SPSS statistical software.

    RESULTS: Total of 50 patients, of which 30 were Malaysians and 20 were foreigners. The mean age of Malaysian patients was 58.3 ± 15.2 years whereas the mean age for foreign patients was 30.3 ± 6.7 years, with foreign patients being significantly younger than local patients. Foreigners had significantly smaller ulcers with only 5% of them having ulcers more than 1cm while 36.7% of Malaysian patients had ulcers more than 1cm. Post-operative complications are significantly higher in Malaysian patients (p<0.05) with 40% of Malaysian patients and 10% of foreign patients developing post-operative complications.

    CONCLUSION: Foreign patients are younger with significantly smaller perforated ulcers and better post-operative outcomes.

    Matched MeSH terms: Peptic Ulcer Perforation/complications; Peptic Ulcer Perforation/surgery*
  8. Ti TK, Yong NK
    Aust N Z J Surg, 1973 May;42(4):353-6.
    PMID: 4532515
    Matched MeSH terms: Peptic Ulcer Perforation/complications; Peptic Ulcer Perforation/mortality; Peptic Ulcer Perforation/epidemiology; Peptic Ulcer Perforation/surgery*
  9. Koh KB, Chang KW
    Singapore Med J, 1992 Oct;33(5):472-3.
    PMID: 1360708
    The treatment of perforated duodenal ulcer is controversial. Since the advent of H2 antagonists, the number of ulcer operations has declined tremendously. We wanted to find out if the addition of a H2 antagonist after simple closure of a perforated duodenal ulcer would change the outcome and therefore reviewed 46 patients treated in this fashion. Our results show that this is a safe and effective way of treating patients with perforated duodenal ulcer.
    Matched MeSH terms: Peptic Ulcer Perforation/drug therapy*; Peptic Ulcer Perforation/surgery*
  10. Siow SL, Mahendran HA
    Surg Laparosc Endosc Percutan Tech, 2014 Apr;24(2):134-9.
    PMID: 24686348 DOI: 10.1097/SLE.0b013e31828fa951
    We propose a standardized technique of repair and lavage with the outcomes of 50 consecutive patients treated at our institution. The perforation was closed primarily and reinforced with omental patch. It was then followed by peritoneal lavage in a focused sequential manner that involved quadrant to quadrant lavage with tilting of operating table and changing of position between the surgeon and the camera surgeon. None of our patients had postoperative intra-abdominal complications, but unfortunately 1 patient succumbed to respiratory complications. Respiratory complications was the most common postoperative complication in our series (9 patients), whereas 2 patients had ileus. There were no leaks or reoperations in our series. Laparoscopic repair and sutured omentoplasty, followed by focused sequential lavage in a systematic manner, if performed diligently, will yield good outcomes.
    Matched MeSH terms: Peptic Ulcer Perforation/surgery*
  11. Faizah MZ, Sharifah MI, Johoruddin K, Juliana AL
    Med J Malaysia, 2011 Oct;66(4):367-8.
    PMID: 22299562 MyJurnal
    Matched MeSH terms: Peptic Ulcer Perforation/etiology*
  12. Jasmi AY, Normala B, al-Amin MD
    Med J Malaysia, 2000 Mar;55(1):135-7.
    PMID: 11072499
    Gastric cancer in the young adult is rare and has been said to be more aggressive than gastric cancers of the older age group. Its unique association with pregnancy is even rarer. However, they have similar complications of haemorrhage, obstruction and perforation. We report a 27 year old lady at 16 weeks gestation who presented with a perforated malignant gastric ulcer and carcinomatosis peritonei. Reviewing the literature, we realised that such complication of a gastric cancer occurring in a pregnant young adult has not been previously documented.
    Matched MeSH terms: Peptic Ulcer Perforation/complications*
  13. Siow SL, Mahendran HA, Wong CM, Hardin M, Luk TL
    Asian J Surg, 2018 Mar;41(2):136-142.
    PMID: 27955872 DOI: 10.1016/j.asjsur.2016.11.004
    BACKGROUND/OBJECTIVE: The objective of this study was to compare the outcomes of patients who underwent laparoscopic and open repair of perforated peptic ulcers (PPUs) at our institution.

    METHODS: This is a retrospective review of a prospectively collected database of patients who underwent emergency laparoscopic or open repair for PPU between December 2010 and February 2014.

    RESULTS: A total of 131 patients underwent emergency repair for PPU (laparoscopic repair, n=63, 48.1% vs. open repair, n=68, 51.9%). There were no significant differences in baseline characteristics between both groups in terms of age (p=0.434), gender (p=0.305), body mass index (p=0.180), and presence of comorbidities (p=0.214). Both groups were also comparable in their American Society of Anesthesiologists (ASA) scores (p=0.769), Boey scores 0/1 (p=0.311), Mannheim Peritonitis Index > 27 (p=0.528), shock on admission (p<0.99), and the duration of symptoms > 24 hours (p=0.857). There was no significant difference in the operating time between the two groups (p=0.618). Overall, the laparoscopic group had fewer complications compared with the open group (14.3% vs. 36.8%, p=0.005). When reviewing specific complications, only the incidence of surgical site infection was statistically significant (laparoscopic 0.0% vs. open 13.2%, p=0.003). The other parameters were not statistically significant. The laparoscopic group did have a significantly shorter mean postoperative stay (p=0.008) and lower pain scores in the immediate postoperative period (p<0.05). Mortality was similar in both groups (open, 1.6% vs. laparoscopic, 2.9%, p < 0.99).

    CONCLUSION: Laparoscopic repair resulted in reduced wound infection rates, shorter hospitalization, and reduced postoperative pain. Our single institution series and standardized technique demonstrated lower morbidity rates in the laparoscopic group.

    Matched MeSH terms: Peptic Ulcer Perforation
  14. Ti TK
    Ann Acad Med Singap, 1983 Oct;12(4):507-17.
    PMID: 6678134
    Basal and pentagastrin stimulated acid output was measured in 80 normal and 179 duodenal ulcer subjects of Chinese, Indian and Malay origin. Basal and maximally stimulated acid output was significantly higher in duodenal ulcer patients compared with normal subjects. There was however considerable overlap and less than one in four duodenal ulcer patients were hypersecretors. The acid output (and hence the parietal cell mass) was lower than in Caucasian subjects and this was possibly related to weight differences. The acid output did not differ significantly in the Chinese, Indian and Malay subjects, suggesting that parietal cell mass in the three racial groups is closely similar. The difference in frequency of duodenal ulcer disease in the three racial groups is thus not related to gastric secretory capacity.
    Matched MeSH terms: Peptic Ulcer Perforation/metabolism
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