The efficacy of xylocaine topical anaesthetic and a placebo in reducing intraoral injection pain were tested in 72 patients. The topical agent was found to be very effective in reducing such pain and the authors recommend its use prior to intraoral injections for the benefit of the patient.
The authors, a psychiatrist and a clinical psychologist, have successfully treated two cases of phobic neurosis by simple behaviour therapy consisting of Jacobson's muscle relaxation technique and systemic desensitisation, at the University Hospital, Kuala Lumpur. The two patients, who were literally housebound because of the unpleasant symptoms of their illness, were able to mobilise themselves again following therapy. The authors feel that general practitioners with some basic training in these methods will be able to bring relief to such afflicted patients. Using the same technique, other conditions such as insomnia, alcoholism and sexual deviations can also be treated.
A patient with a left atrial myxoma is reported to illustrate the value of two dimensional real time echocardiography in the diagnosis of intracavitary cardiac tumours.
A case of amoebiasis with colonic perforation and ruptured liver abscess is reported. It is rare for both these complications to occur in the same patient. The management is described and the literature reviewed
One hundred and forty-five diabetic patients attending diabetic clinic over a four week period were fully examined in an adjacent eye clinic. The fundi were examined with a Halogen light direct ophthalmoscope and the Binocular Indirect Ophthalmoscope after mydriasis to assess the presence of retinopathy. 44.1 percent of patients examined had Opbthalmoscopicaliy detectable retinopathy while 11 percent were found to have 'serious diabetic eye disease'. The prevalence of diabetic retinopathy in Malaysia is comparable to those of Western countries and Japan.
Study site: Diabetic clinic, University Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia
A recent anthropometric study of Sabah reported that 37.1 percent of children were nutritional dwarfs, 12.5 percent were acutely malnourished and 9.4 percent were stunted and wasted. It was also noted that Muruts were among the top five most malnourished ethnic groups in Sabah. The present study looks at the ecological basis of malnutrition among Muruts and concludes that a variety of interrelated factors, including the lack of education, climatic and soil conditions, poverty, food habits and taboos as well as diseases from poor sanitation and malaria contribute to the presence of malnutrition among rural Muruts. It is recommended that a multidisciplinary approach be taken to control and prevent malnutrition among the Muruts and that the single most important measure aside from malaria control is education of the people and the development of marketable skills.
Tetanus, especially tetanus neonatorum (T.N.) continues to be a significant medical and social problem in the developing countries. The case mortality rate remains very high even in the 'developed' countries, varying from 60-80 percent in various reports, and even higher in the case of tetanus neonatorum. Sanders et al had introduced the method of intrathecal injection of antitetanus serum (ATS) in 1976 and have achieved very encouraging results. As the conventional treatment of tetanus neonatorum had achieved very poor result, even in the very sophisticated centres, a case of tetanus neonatorum admitted to Cottage Hospital Semporna in Sabah had been treated with intrathecal ATS since June 1982. This paper reviews the results of this new approach to tetanus neonatorum treatment as compared to cases treated conventionally.
Trinervita-1(15),8(19)-dien-2β,3α-diol and the new trinervita-1(15),8(19)-dien-2β, 3α-diol 2-O-acetate constitute the major diterpene constituents of the soldier defense secretions of the NasutitermiteHospitalitermes umbrinus of Malaysian region. Studies on the intraspecific variations on sympatric and allopatric populations indicate two distinct patterns of chemical composition.
The forfeiture of the proceeds of drug-related offences does not seem to have received much attention as yet from British Commonwealth countries. Whereas in some of these countries specific legislation exists in relation to forfeiture, in many other countries the act of forfeiture falls within the purview of general criminal law. Forfeiture presupposes enquiry and search, two procedures which involve integral aspects of present-day human rights law, and which seem to be impeded at almost every stage of the process concluding in forfeiture. Time and the procedure for execution of judgments seem to be two significant factors in the successful enforcement of forfeiture judgments. Unfortunately, given the present practice of maintaining inviolability of bank secrecy, effective enforcement of forfeiture judgments is not possible. Perhaps an international convention may offer some assistance in the successful implementation of a forfeiture judgment, especially where the ill-gotten gains have been transferred to a foreign jurisdiction.
MeSH terms: Australia; Canada; Criminal Law; Drug and Narcotic Control/legislation & jurisprudence*; Gambia; Great Britain; Hong Kong; International Cooperation; Kenya; Malaysia; Mauritius; New Zealand; Nigeria; Singapore; Zambia
From a total of 163 renal biopsies there were 12 cases (9.1%) of IgA nephropathy. All of them presented with symptomatic or asymptomatic proteinuria and/or haematuria. The pattern of disease here generally conforms to reports elsewhere. However in contrast it appears to be common in both sexes and the clinical course tends to be more severe In males. The absence of IgG In the glomeruli on immunoffourescence was an unexpected finding. The presence of hypertension, renal insufficiency and glomerulo·interstitial scarring seem to indicate poorer prognosis. There is no known effective treatment.
Cleft lip and palate is the most common congenital abnormality seen in the Department of Plastic Surgery, Singapore General Hospital. A total of 461 operative cases seen over a period of 5 years (1977 to 1981) is analysed. There is a relatively high incidence in the Singapore population of 2.0 per 1000 live births. In both cleft lip and cleft palate deformities, there is no significant difference in the sex distribution. The cleft patterns show that 78% of the cases are unilateral clefts, 53% are left sided, 25% are right sided and 22% of the cases are bilateral clefts.
MeSH terms: China/ethnology; Cleft Lip/epidemiology*; Cleft Palate/epidemiology*; Female; Humans; India/ethnology; Lip/pathology; Malaysia/ethnology; Male; Palate/pathology; Sex Factors; Singapore; African Continental Ancestry Group; European Continental Ancestry Group; Asian Continental Ancestry Group
The diagnostic value of the Widal test was assessed in an endemic area. The test was done on 300 normal individuals, 297 non-typhoidal fevers and 275 bacteriologically proven cases of typhoid. Of 300 normal individuals, 2% had an H agglutinin titre of 1/160 and 5% had an O agglutinin titre of 1/160. On the basis of these criteria a significant H and/or O agglutinin titre of 1/320 or more was observed in 93-97% of typhoid cases and in only 3% of patients with non-typhoidal fever. Of the sera from typhoid cases which gave a significant Widal reaction, the majority (79.9%) showed increases in both H and O agglutinins and 51 of 234 (21.8%) of these sera were collected in the first week of illness. The significance and implications of these findings are discussed.
The histopathology of gastric papillomas in 17 crab-eating monkeys from Indonesia and Malaysia was investigated. The changes in the affected mucosa consisted of papillomatous proliferation with accidental heterotopia, desquamation or necrosis of the epithelium associated with eggs or adults of the small nematode Nochtia nochti, inflammatory cell infiltration and haemorrhage or oedema and fibrosis. The primary pathogenic effect of this parasite was due to its irritant action on the gastric mucosa. Hyper-regeneration, with a downward shift of the proliferating zone in the gastric gland and an inflammatory process, appeared to play a significant role in the morphogenesis of this lesion. It is concluded that the gastric papilloma associated with Nochtia nochti in the monkey is a parasitic inflammatory polyp.
Based on an improved C-banding technique, the C-banding patterns of all 11 diploid Aegilops species were described and compared. All diploid species exhibit characteristically different patterns which enable the chromosomes of any complement to be identified individually. These patterns confirm existing genome symbols and provide further evidence for the suggested changes in genome symbols of Ae. umbellulata and Ae. sharonensis, U and S(sh) respectively. Furthermore, Ae. uniaristata should be given a separate symbol, probably N. Aegilops speltoides and Ae. sharonensis could be possible donors to the B genome of wheat. Interspecific divergence in these diploid species has been accompanied by either amplification or deletion as well as massive repatterning of heterochromatin from the centromere to the telomere.
The present study reports on a successful treatment of a single case of obsessive compulsive neurosis using a behavioural technique, namely, systematic desensitisation. Much recent literature has suggested that behavioural techniques may be more helpful with this particularly difficult condition than traditional methods of treatment, such as medication. The present results suggest that the technique of systematic desensitisation may be successfully used in a non-western setting.