Browse publications by year: 2021

  1. WAN NAQIYAH WAN ABDUL MAJID, ROHANA AHMAD
    MyJurnal
    Keusahawanan sering dianggap sebagai subjek yang lebih cenderung kepada pelajar dalam bidang perniagaan tetapi tidak untuk pelajar yang mempunyai pelbagai kemahiran yang terlibat dalam bidang teknikal. Namun, ini adalah satu tanggapan yang tidak seharusnya wujud kerana Malaysia seharusnya perlu mengenal pasti kesedaran keusahawanan dalam bidang teknikal. Pada masa kini, kesedaran keusahawanan dalam bidang teknikal tertentu adalah kurang lantaran program keusahawanan lazimnya lebih tertumpu kepada pelajar InstitusiPengajian Tinggi (IPT). Misalnya, Pembangunan Keusahawanan Bumiputera adalah lebih tertumpu kepada golongan siswazah IPT, belia dan wanita. Dasar Pembangunan Keusahawanan IPT juga diperkenalkan agar modal insan dengan daya pemikiran, atribut dan nilai keusahawanan dalam kalangan IPT tempatan dapat dilahirkan. Tujuan kajian ini dijalankan adalah untuk mengenal pasti tahap kesedaran keusahawanan dalam kalangan pelajar Institut Latihan Perindustrian (ILP) di Terengganu berhubung dengan faktor keusahawanan dari aspek individu usahawan yang berbeza serta struktur dan persekitaran perniagaan. Seterusnya, mengkaji hubungan antara kesedaran keusahawanan dengan pembolehubah tidak bersandar lain yang berkait dengan kajian seperti ciri keusahawanan dan cabaran keusahawanan. Kaedah kuantitatif telah digunakan dan borang soal selidik diedarkan kepada 280 orang pelajar. Hasil analisis regresi berganda menunjukkan bahawa cabaran keusahawanan merangkumi sikap dan minat, kemahiran keusahawanan serta pendidikan dan pengetahuan keusahawanan merupakan elemen paling signifikan yang mempengaruhi kesedaran keusahawanan dalam kalangan pelajar berkemahiran diILP untuk menjadi seorang usahawan. Oleh itu, adalah sangat penting bagi kerajaan Malaysiauntuk memberi perhatian terhadap cabaran yang dihadapi oleh para pelajar ini dan mengambil tindakan terhadap segala kemungkinan yang boleh mempengaruhi atau memberi kesan kepada minat pelajar terhadap keusahawanan pada masa akan datang.
    MeSH terms: Agar; Color; Environment; Malaysia; Pallor; Fenofibrate
  2. NURUL NADHILAH FEIZAL, SHAHNAZ ISMAIL, WAN ZURIATI WAN ZAKARI, NADIA MOHD NAWI
    MyJurnal
    The advancement of technology in digital revolution such as Internet of Things has gained attention in all over the world. This myriad of technology innovations affects all aspects of the human lives today. The generation who has grown up during this era, knownastheiGens,mostlyreliesonthetechnologyineveryaspectoftheirlives,including education. Thus, technology also gives profound impact in educational transformation nowadays to convey innovative education. However, lack of innovation in education becomes a challenge to meet this demand. Therefore, this study was carried out with the aim to discover factors which may affect academic performance of the iGen students in the university. A total of 250 self-administered questionnaires were distributed to the accountingstudentsatUMTwitharesponserateof93.6%(234).Usingmultipleregression analysis, the findings showed that parental involvement and student’s attitude contribute more towards academic performance of iGen students rather than the technology itself. This finding showed that human factor such as support fromtheir parents and individual factor are vital towards their academic performance regardless of from technology savvy generation or not.
    MeSH terms: Attention; Educational Status; Family Characteristics; Humans; Parents; Surveys and Questionnaires; Students; Universities; Inventions
  3. SITI DIANA KAMILA NADIM, JARINA MOHD JANI
    MyJurnal
    Investing in natural cosmetics contributes to the sustainability of natural resources in two ways – the emission of less harmful by-products, and the conservation of ecosystems through sustainable harvesting of resources. Therefore, studying students’ (millennials’) behaviour and attitude towards these products may help improve awareness-raising approaches on their benefits for local market acceptance. A study was conducted in Universiti Malaysia Terengganu (UMT), Malaysia with the aim to understand the current perception and habits of UMT students towards natural cosmetics and their readiness to convert to natural cosmetics. 521 responses were collected through an online survey that focused on three themes: Stage of Change, Decisional Balance Inventory, and Product Knowledge and Perception. The study found that most of the respondents (79%) claim to be using natural cosmetics, while only nine percent are not considering at all. Eighty-six percent of those users practice label reading habits although most respondents could not distinguish natural cosmetics from synthetic ones if solely based on personal knowledge and appearance of product. This proves that product design does influence customers’ purchasing behaviours. Moreover, results indicate that existing natural cosmetic users are quite likely to maintain the habit, while others are still indecisive. Meanwhile, label reading habits are quite likely to be maintained by many respondents. Hence, based on results, businesses should acknowledge that there is a demand in natural cosmetics among Malaysian millennials, and should increase their promotional activities, improve product design and affordability in order to grab consumers’ attention to switch from synthetic to natural cosmetics.
    MeSH terms: Natural Resources; Attention; Consumer Behavior; Cosmetics; Costs and Cost Analysis; Habits; Humans; Malaysia; Perception; Surveys and Questionnaires; Reading; Students; Ecosystem
  4. RUQAYYAH SOLEHAH ABU HANIPAH, NOR AIZAL AKMAL ROHAIZAD, MOHD IZZAMUDDIN NADIN
    MyJurnal
    There is sufficient evidence regarding the potential risk of mobile phone use on anxiety. Therefore, the aim of research was to examine the relationship between mobile phone use and anxiety among students from two faculties in University TeknologI Mara (UiTM) Seremban. This cross-sectional study included 317 students of both genders. The sampling method was measured using proportionate stratified sampling. Level of mobile phone use was measured using Problem Use Mobile Phone (PUMP) Scale and level of an anxiety was measured using Beck Anxiety Inventory (BEI) Scale. In Malaysia, there are very small amount who made this research. The finding of this study showed that majority respondents are at normal level for mobile phone use. Pearson correlation result shows there was significant correlation between mobile phone use with an anxiety among students. This study indicates the important mobile phone use toward an anxiety among university students.
    MeSH terms: Anxiety; Anxiety Disorders; Cross-Sectional Studies; Female; Humans; Malaysia; Male; Surveys and Questionnaires; Students; Universities
  5. KIEW CHEE CHING, ZUHA ROSUFILA ABU HASAN, NADIA ABU HASAN
    MyJurnal
    Shopee online has become increasingly popular among consumers for purchasing purposes as compared to brick-and-mortar retail due to the benefits and enjoyment that come with it. However, Shopee has facing intense competitive challenges with other competitors in Malaysia. In addition, it is also difficult for Shopee to compete with major leader of online shopping portal although this platform offers the same function and usage as its contender. Hence, it is important to understand consumer perceptions on the benefit and intention of using Shopee. This study examines consumer perceived usefulness, perceived ease of use, perceived price, perceived convenience and perceived trust adapted from the Technology Acceptance Model (TAM). 208 respondents who have experience online purchasing in East Cost of Malaysia were invited to participate in this study using online survey. Data were analyzed using descriptive, correlation and multiple regression analyses. The findings show that perceived convenience and perceived trust have strong influence towards consumer intention to use Shopee as platform to do online purchase. It is suggested that this study will help practitioners to understand consumer online shopping perception and intention in order to induce visitation and usage of Shopee.
    MeSH terms: Consumer Behavior; Happiness; Malaysia; Perception; Surveys and Questionnaires; Regression Analysis; Technology; Intention; Trust; Marketing; Pleasure
  6. FAIQAH MOHAMAD FUDZI, ZAHAYU MD YUSOF, MASNITA MISIRAN
    MyJurnal
    The prediction of rainfall on monthly and seasonal time scales is not only scientifically challenging but is also important for planning and devising agricultural strategies. In this paper, the study is conducted to examine the pattern of monthly rainfall in Alor Setar, Kedah within ten years which is from 2008 to 2018. This paper considered a model based on real data that obtained from Department of Meteorology Malaysia. This study indicates that the monthly rainfall in Alor Setar has a seasonal and trend pattern based on yt vs t plotting, autocorrelation function and Kruskal Wallis Test for seasonality. The examined rainfall time-series modelling approaches include Naïve Model, Decomposition Method, Holt-Winter’s and Box-Jenkins ARIMA. Multiplicative Decomposition Method was identified as the best model to forecast rainfall for the year of 2019 by analysing the previous ten-year’s data (2008-2018).As a result from the forecast of 2019, October is the wettest month with highest forecasted rainfall of 276.15mm while the driest month is in February with lowest forecasted rainfall of 50.55mm. The model is therefore adequate and appropriate to forecast future monthly rainfall values in the catchment which can help farmers to plan their farming activities ahead of time.
    MeSH terms: Farmers; Agriculture; Forecasting; Humans; Malaysia; Seasons; Meteorology; Farms
  7. CHUA KAH WAI, LOY KAK CHOON, RUWAIDIAH IDRIS
    MyJurnal
    Ordinary Differential Equations (ODEs) are usually used in numerous fields especially in solving the modelling problem. Numerical methods are one of the vital mathematical tools to solve the ODEs that appear in various modelling problems by determining the approximation solution close to the in exact solution if it exists. Runge-Kutta methods (RK) are the numerical methods used to integrate the ODEs by applying multistage methods at the midpoint of an interval which can efficiently produce a more accurate result or small magnitude of error. We proposed Runge-Kutta methods (RK) to solve the 1st_ order nonlinear stiff ODEs. The RK methods used in this research are known as the RK-2, RK-4, and RK-5 methods. We proved the existence and uniqueness of the ODEs before we solved it numerically. We also proved the absolute-stability of the RK methods to determine the overall stability of these methods. We found two suitable test cases which are the standard test problem and manufactured solution. We proved that by combining the adaptive step size with RK methods can result in more efficient computation. We implemented the 2nd_, 4th_ and 5th_ order of RK methods with step size adaptively algorithm to solve the test problem and manufactured solution via Octave programming language. The resulting numerical error and the stability of each method can be studied. We compared our results using several error plots versus the Central Processing Unit (CPU) time required to compute a given nonlinear 1st_ order stiff ODE problem. In a conclusion, RK methods which combine with the adaptive step size can result in more efficient computation and accuracy compare with the fixed step size RK methods.
    MeSH terms: Algorithms; Mathematics; Programming Languages; Reference Standards; Research Design
  8. LIM XUE YEN, AHMAD FITRIADHY
    MyJurnal
    Concerning on navigational safety of a ship, comprehensive investigation of manoeuvrability of the ship is prominently required. The turning instability due to improper speed and magnitude of the rudder angle is vulnerable to serious accidents such as collision especially in the confined waters. This paper presents a computational fluid dynamic analyses on manoeuvrability performance of a tug in calm water. Here, the characteristics of the turning ability and zig-zag characteristics of the tug has been assessed due to effect of the various angles of twin-rudder and turning speeds. The results revealed that the increase of rudder’s angle resulted in subsequent reduction of her advance diameter from 144 m, 108 m, 96 m to 92 m. While for zig zag manoeuvre, the first overshoot angle is 0.6° and 1.08° for 10°/10° and 20°/20° rudder’s angle respectively. The first overshoot and second overshoot angle are within the IMO criteria which is below 20° and 25°. However, the increase of turning speed from 7 knots to 9 knots has been proportional with the increase of the turning diameter (advance diameter) from 70 m to 105.2 m. Basically, the turning performances of the tug manoeuvring with the turning speed of 7 to 9 knots incorporated with rudder’s angle 20°, 25°, 30° and 35° have been complied with IMO manoeuvring standards. This preliminary analysis contributes very valuable findings at early ship design stage to provide a safety of the navigational guidance for turning ability of the tug.
    MeSH terms: Accidents; Diagnostic Tests, Routine; Female; Reference Standards; Ships; Water; Reconstructive Surgical Procedures; Hydrodynamics
  9. PEI YING LEE, YUSRI YUSOF, MELISSA BEATA MARTIN
    MyJurnal
    This study focuses on the parasites in Dascyllus trimaculatus fish in Bidong Island. Though D. trimaculatus is a common reef fish, there is lack on parasites studies of this fish in Malaysia. The objectives of this study are to identify metazoan parasites and analyse the prevalence and mean intensity the parasites in D. trimaculatus. Sampling was randomly conducted on a coral colony of 100 meters within a 15m depth at Pantai Pasir Cina,BidongIsland.ThisresearchresultedintheidentificationofacopepodLernaeocera branchialis and a nematode from the family Camallanidae. The copepods collected in this study infected 20 out of 42 D. trimaculatus specimens, whereas the nematode-like parasites collected infected 18 of out of 42 D. trimaculatus. All copepods found in the gills of D. trimaculatus had a prevalence of 4.95 and mean intensity of 47.62%, while the nematode-like parasite, which were found in the brain, had 2.72 prevalence and 42.86% mean intensity. This elucidates that both parasites are categorised as having light levelbut common frequency of infection, and the current IUCN status of D. trimaculatus has not been reported to be harmedby parasites. Though the mean intensity of both parasites isnot harmful, the prevalence are concerning and might increase in the future, with further incorporation and monitoring of climate change factors that may affect the damselfish.
    MeSH terms: Animals; Brain; Fishes; Gills; Malaysia; Parasites; Perciformes; Prevalence; Spirurida; Copepoda; Anthozoa; Climate Change; Islands
  10. NUR ATHIRAH ZULKIFLI, MOHD AIDIL ADHHA ABDULLAH, MAZIDAH MAMAT
    MyJurnal
    Polymer had been widely used in industries nowadays. However, the properties of the polymer itself are limited to a particular application. This study describes synthetic clay, layered double hydroxide (LDH), as a filler in low-density polyethylene (LDPE) composite. LDHs of magnesium/aluminium-dodecyl sulfate (Mg/Al-DS) and its grafted with triethoxymethylsilane (TEMS), (TEMS-g-Mg/Al-DS) were synthesized through co-precipitation and salinization reaction methods. The presence of alkyl group, v(C-H) in both LDH had confirmed through Fourier transform infrared (FTIR). The appearance of peaks in FTIR spectra within the absorbance range of 2800 – 2930 cm-1indicates a successful surface modification of LDH, supported by the changes of interlayer spacing and the presence of carbon from X-ray diffractogram and CHNS elemental analysis, respectively. The synthesized LDH was mixed with LDPE via melt intercalation method. The LDH modification resulted in higher interaction and compatibility between the LDPE matrix and LDH by the formation exfoliated type of nanocomposites, as suggested by XRD analysis.
    MeSH terms: Aluminum; Carbon; Fourier Analysis; Hydroxides; Intercalating Agents; Magnesium; Polymers; Sodium Dodecyl Sulfate; X-Rays; Spectroscopy, Fourier Transform Infrared; Polyethylene; Nanocomposites
  11. Ong C, Tan RKJ, Le D, Tan A, Tyler A, Tan C, et al.
    BMC Public Health, 2021 05 22;21(1):971.
    PMID: 34022843 DOI: 10.1186/s12889-021-10992-6
    BACKGROUND: Gay, bisexual and queer (GBQ) men are frequently subjected to minority stressors that have negative impacts on their health. Milestones that include the acceptance and disclosure of sexual identity amongst GBQ men are hence key instruments in understanding the prevalence of internalised homophobia and predicting health outcomes. As such, this work takes a novel approach to deduce the correlates of delayed acceptance of sexual orientation in young GBQ men as a measure of internalised homophobia through retrospective self-reporting and age-based analysis.

    METHODS: Participants were recruited as part of a cohort study exploring the syndemic risks associated with HIV acquisition among young GBQ men in Singapore. We examined their levels of internalised, perceived, experienced homophobia, as well as their health behaviours and suicidal tendencies. Two separate variables were also self-reported by the participants - the age of questioning of sexual orientation and the age of acceptance of sexual orientation. We subsequently recoded a new variable, delayed acceptance of sexual orientation, by taking the difference between these two variables, regressing it as an independent and dependent variable to deduce its psychosocial correlates, as well as its association with other measured instruments of health.

    RESULTS: As a dependent variable, delayed acceptance of sexual orientation is positively associated with an increase of age and internalised homophobia, while being negatively associated with reporting as being gay, compared to being bisexual or queer. As an independent variable, delayed acceptance of sexual orientation was associated with a delayed age of coming out to siblings and parents, suicide ideation, historical use of substances including smoking tobacco cigarettes and consuming marijuana, as well as reporting higher levels of experienced, internalised and perceived homophobia.

    CONCLUSION: Greater levels of early intervention and efforts are required to reduce the heightened experience of minority stress resulting from communal and institutional hostilities. Areas of improvement may include community-based counselling and psychological support for GBQ men, while not forsaking greater education of the social and healthcare sectors. Most importantly, disrupting the stigma narrative of a GBQ 'lifestyle' is paramount in establishing an accepting social environment that reduces the health disparity faced by GBQ men.

    MeSH terms: Bisexuality; Female; Floors and Floorcoverings; Humans; Male; Retrospective Studies; Sexual Behavior; Singapore/epidemiology; Cohort Studies; Homosexuality, Male; Substance-Related Disorders*; Suicidal Ideation; Homophobia; Sexual Minorities*
  12. Yusoff MSB, Hadie SNH, Yasin MAM
    BMC Med Educ, 2021 May 22;21(1):293.
    PMID: 34022865 DOI: 10.1186/s12909-021-02733-5
    BACKGROUND: Stress and burnout commonly threaten the mental health of medical students in Malaysia and elsewhere. This study aimed to explore the interrelations of psychological distress, emotional intelligence, personality traits, academic stress, and burnout among medical students.

    METHODS: A cross-sectional study was conducted with 241 medical students. Validated questionnaires were administered to measure burnout, psychological distress, emotional intelligence, personality traits, and academic stress, respectively. A structural equation modelling analysis was performed by AMOS.

    RESULTS: The results suggested a structural model with good fit indices, in which psychological distress and academic stress were noted to have direct and indirect effects on burnout. The burnout levels significantly increased with the rise of psychological distress and academic stress. Neuroticism was only found to have significant indirect effects on burnout, whereby burnout increased when neuroticism increased. Emotional intelligence had a significant direct effect on lowering burnout with the incremental increase of emotional intelligence, but it was significantly reduced by psychological distress and neuroticism.

    CONCLUSION: This study showed significant effects that psychological distress, emotional intelligence, academic stress, and neuroticism have on burnout. Academic stress and neuroticism significantly increased psychological distress, leading to an increased burnout level, while emotional intelligence had a significant direct effect on reducing burnout; however, this relationship was compromised by psychological distress and neuroticism, leading to increased burnout. Several practical recommendations for medical educators, medical students, and medical schools are discussed.

    MeSH terms: Cross-Sectional Studies; Humans; Malaysia/epidemiology; Surveys and Questionnaires; Stress, Psychological/epidemiology; Students, Medical*; Emotional Intelligence
  13. Zhao C, Wang G, Zhang M, Wang G, de With G, Bezhenar R, et al.
    Mar Pollut Bull, 2021 May 21;169:112515.
    PMID: 34023585 DOI: 10.1016/j.marpolbul.2021.112515
    Japan recently announced plans to discharge over 1.2 million tons of radioactive water from the Fukushima Daiichi Nuclear Power Plant (FDNPP) into the Pacific Ocean. The contaminated water can poses a threat to marine ecosystems and human health. To estimate the impact of the plan, here, we developed a three-dimensional global model to track the transport and dispersion of tritium released from the radioactive water of the FDNPP. The pollution scenarios for four release durations (1 month, 1 year, 5 years, and 10 years) were simulated. The simulation results showed that for the release in short-duration scenarios (1 month and 1 year), the peak plume with high tritium concentration shifted with the currents and finally reached the northeastern Pacific. For the long-duration scenarios (5 years and 10 years), the peak plume of the contaminated water was confined to coastal regions east of Japan.
  14. Chiu CK, Tan CS, Chung WH, Mohamad SM, Kwan MK, Chan CYW
    Eur Spine J, 2021 07;30(7):1978-1987.
    PMID: 34023966 DOI: 10.1007/s00586-021-06874-5
    PURPOSE: To investigate mid-long-term effects of the lowest instrumented vertebra (LIV) selection on adolescent idiopathic scoliosis (AIS) patients who had posterior spinal fusion (PSF) surgery.

    METHODS: Forty-eight patients were recruited. Inclusion criteria were AIS patients who have had PSF surgery more than 10 years ago. Patients were divided into G1: LIV L3 or higher and G2: LIV L4 or lower. MRI evaluation was classified using Pfirrmann grades. Pfirrmann scores were average of Pfirrmann grades for all unfused discs below LIV. SRS-22r, SF-36, Oswestry Disability Index (ODI) and Modified Cincinnati Sports Activity Scale (MCSAS) were used.

    RESULTS: There were 19 patients in G1 and 29 patients in G2. Demographic parameters showed no significant differences. We found no significant differences in Pfirrmann grades or scores between G1 and G2. There was significant correlation between age and mean Pfirrmann scores (r = 0.546, p 

    MeSH terms: Adolescent; Follow-Up Studies; Humans; Intervertebral Disc*; Kyphosis*; Lumbar Vertebrae/surgery; Retrospective Studies; Treatment Outcome
  15. Harun MA, Safari MJS, Gul E, Ab Ghani A
    Environ Sci Pollut Res Int, 2021 Oct;28(38):53097-53115.
    PMID: 34023993 DOI: 10.1007/s11356-021-14479-0
    The investigation of sediment transport in tropical rivers is essential for planning effective integrated river basin management to predict the changes in rivers. The characteristics of rivers and sediment in the tropical region are different compared to those of the rivers in Europe and the USA, where the median sediment size tends to be much more refined. The origins of the rivers are mainly tropical forests. Due to the complexity of determining sediment transport, many sediment transport equations were recommended in the literature. However, the accuracy of the prediction results remains low, particularly for the tropical rivers. The majority of the existing equations were developed using multiple non-linear regression (MNLR). Machine learning has recently been the method of choice to increase model prediction accuracy in complex hydrological problems. Compared to the conventional MNLR method, machine learning algorithms have advanced and can produce a useful prediction model. In this research, three machine learning models, namely evolutionary polynomial regression (EPR), multi-gene genetic programming (MGGP) and M5 tree model (M5P), were implemented to model sediment transport for rivers in Malaysia. The formulated variables for the prediction model were originated from the revised equations reported in the relevant literature for Malaysian rivers. Among the three machine learning models, in terms of different statistical measurement criteria, EPR gives the best prediction model, followed by MGGP and M5P. Machine learning is excellent at improving the prediction distribution of high data values but lacks accuracy compared to observations of lower data values. These results indicate that further study needs to be done to improve the machine learning model's accuracy to predict sediment transport.
    MeSH terms: Machine Learning; Algorithms; Regression Analysis; Geologic Sediments*; Rivers*
  16. Kuay LK, Chin TB, Ying CY, Hussain H, Mahmud NA, Kassim MSA, et al.
    Food Nutr Bull, 2021 09;42(3):406-413.
    PMID: 34024187 DOI: 10.1177/03795721211002079
    BACKGROUND: A mandatory universal salt iodization (USI) has been implemented in Sarawak, Malaysia since 2008.

    OBJECTIVES: The aim of this study is to assess the current iodine status among school-aged children (SAC) and pregnant women (PW) after 10 years of USI implementation in Sarawak.

    METHODS: This cross-sectional survey among school-aged children and pregnant women was conducted between July and October 2018 in Sarawak. The multistage proportionate to population size sampling technique was used to select 30 schools and 30 maternal and child health care clinics. A total of 1200 children aged 8 to 10 years and 750 first-trimester pregnant women were randomly selected to participate in the study. Iodine excretion level in urine was determined according to the World Health Organization classification.

    RESULTS: A total of 988 children and 677 PW participated in the study with a response rate of 82.3% and 90.2%, respectively. The overall median urinary iodine concentration (UIC) level among the children was 126.0 μg/L (interquartile range [IQR], 71.0-200.9 μg/L) and classified as adequate iodine status. The median UIC among PW was 123.9 μg/L (IQR, 56.5-192.1μg/L) indicating inadequate iodine status.

    CONCLUSION: The present findings indicate that despite adequate iodine status in children, the majority of PW still showed inadequate iodine status. Thus, comprehensive monitoring of the iodine deficiency disorder problem among PW is warranted.

    MeSH terms: Child; Cross-Sectional Studies; Female; Humans; Iodine*; Malaysia/epidemiology; Nutritional Status; Pregnancy; Schools; Sodium Chloride, Dietary; Pregnant Women
  17. Yong SJ
    Infect Dis (Lond), 2021 Oct;53(10):737-754.
    PMID: 34024217 DOI: 10.1080/23744235.2021.1924397
    Long COVID or post-COVID-19 syndrome first gained widespread recognition among social support groups and later in scientific and medical communities. This illness is poorly understood as it affects COVID-19 survivors at all levels of disease severity, even younger adults, children, and those not hospitalized. While the precise definition of long COVID may be lacking, the most common symptoms reported in many studies are fatigue and dyspnoea that last for months after acute COVID-19. Other persistent symptoms may include cognitive and mental impairments, chest and joint pains, palpitations, myalgia, smell and taste dysfunctions, cough, headache, and gastrointestinal and cardiac issues. Presently, there is limited literature discussing the possible pathophysiology, risk factors, and treatments in long COVID, which the current review aims to address. In brief, long COVID may be driven by long-term tissue damage (e.g. lung, brain, and heart) and pathological inflammation (e.g. from viral persistence, immune dysregulation, and autoimmunity). The associated risk factors may include female sex, more than five early symptoms, early dyspnoea, prior psychiatric disorders, and specific biomarkers (e.g. D-dimer, CRP, and lymphocyte count), although more research is required to substantiate such risk factors. While preliminary evidence suggests that personalized rehabilitation training may help certain long COVID cases, therapeutic drugs repurposed from other similar conditions, such as myalgic encephalomyelitis or chronic fatigue syndrome, postural orthostatic tachycardia syndrome, and mast cell activation syndrome, also hold potential. In sum, this review hopes to provide the current understanding of what is known about long COVID.
    MeSH terms: Mental Disorders*; Female; Humans; Risk Factors
  18. Ong ALC, Lee SH, Aung SW, Khaing SL, Ramasamy TS
    Cells Dev, 2021 03;165:203659.
    PMID: 34024336 DOI: 10.1016/j.cdev.2021.203659
    Successful outcomes of cell-based therapeutic is highly-dependent on quality and quantity of the cells. Epigenetic modifiers are known to modulate cell fates via reprogramming, hence it is plausible to use them in enhancing the plasticity of mesenchymal stem cells. In this study, we aimed to study the effects of 5-Azacytidine (5-AzaCR), an epigenetic modifier, pretreatment on mesenchymal stem cells-derived from Wharton's Jelly (WJMSCs) fates. WJMSCs were pretreated with 5-AzaCR for 24 h and subsequently cultured in culture media mixtures. The proliferative and stemness characteristics of the pretreated WJMSCs were assessed through morphological and gene expression analyses. Results showed that cells pretreated with 5 μM to 20 μM of 5-AzaCR showed to acquire higher proliferative state transiently when cultured in embryonic-mesenchymal stem cell (ESC-MSC) media, but not in MSC medium alone, and this coincides with significant transitional upregulation of stemness transcription factors. 5-AzaCR pretreatment has potential to confer initial induction of higher state of stemness and proliferation in WJMSCs, influenced by the culture media.
  19. Khoa TND, Shaharom-Harrison F
    Vet Parasitol Reg Stud Reports, 2021 Apr;24:100576.
    PMID: 34024392 DOI: 10.1016/j.vprsr.2021.100576
    The caligid parasite Caligus coryphaenae has been reported in several marine fishes from Japan. In this study, a total of 223 wild yellowtail (Seriola quinqueradiata) were collected from Kagoshima fish market, separated into three groups according to total length (TL  70 cm), and examined for C. coryphaenae infection. A total of 518 specimens of C. coryphaenae were isolated giving an overall prevalence of infection and mean intensity of 24.2% and 4.7 ± 3.5, respectively. Body surface, fins and operculum of hosts TL > 50 cm were recorded as preferred sites for the attachment of C. coryphaenae. Of female specimens, 56.7% bore egg strings with various egg string lengths (7.1 ± 1.2 mm), carrying from 98 to 140 eggs (0.06 ± 0.005 mm in length) per each string. To our knowledge, this is the first report of C. coryphaenae infection from wild yellowtail in Japanese waters and globally. This parasite has not been reported in yellowtail culture to date, but the finding on wild specimens of yellowtail means that it poses a risk to their culture.
    MeSH terms: Animals; Female; Fishes; Japan; Parasites; Perciformes; Prevalence; Copepoda; Animal Fins
  20. Sundar VV, Sehu Allavudin SF, Easaw MEPM
    Clin Nutr ESPEN, 2021 06;43:353-359.
    PMID: 34024540 DOI: 10.1016/j.clnesp.2021.03.024
    BACKGROUND & AIMS: Inadequate nutrition delivery in critically ill children has shown associated with poor clinical outcomes. Therefore, identifying barriers to deliver adequate nutrition is vital. The aim of this study was to identify factors influencing adequate protein and energy delivery among critically ill children with heart disease in pediatric intensive care unit (PICU).

    METHODS: This single-centre prospective study, involved children aged from birth to 3 years old, admitted to PICU longer than 72 hours. They received either enteral nutrition (EN) or combination of EN and partial parenteral nutrition (PPN). Clinical and nutrition delivery characteristics were recorded from admission until transferred out of PICU. Multiple regression analysis at significant level p 

    MeSH terms: Child; Enteral Nutrition; Heart Diseases*; Humans; Prospective Studies; Intensive Care Units, Pediatric; Critical Illness*
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