Affiliations 

  • 1 Department of Biostatistics, School of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran
  • 2 Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran
  • 3 Department of Anatomical Sciences, Medical School, Baqiyatallah University of Medical Sciences, Tehran, Iran
  • 4 Department of Computer Engineering, Sharif University of Technology, Tehran, Iran
  • 5 Department of Biology, Faculty of Science, University Putra Malaysia, Serdang, Selangor, Malaysia
  • 6 Cellular and Molecular Research Center, Gerash University of Medical Sciences, Gerash, Iran
  • 7 Department of Obstetrics and Gynecology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
  • 8 Cellular and Molecular Research Center, Gerash University of Medical Sciences, Gerash, Iran. Masoud.mohammadi1989@yahoo.com
Arch Womens Ment Health, 2022 Dec;25(6):1021-1027.
PMID: 36445469 DOI: 10.1007/s00737-022-01281-1

Abstract

The increased number of female smokers is considered a global health challenge in recent years. One of the detrimental effects of smoking is sexual hormone fluctuation causing female sexual dysfunction (FSD). This systematic review and meta-analysis aimed to investigate the effects of smoking leading to FSD. Electronic databases (PubMed, Scopus, Web of Science, Embase, Science Direct, and Google Scholar) were hired for systematic searching. Until June 2022, whole qualified studies reporting the consequences of smoking on FSD were gathered for data analysis based on the random effects model (CMA software, v.2). Study heterogeneity and publication bias were also assessed using I2 index and Egger test, respectively. Ten eligible studies with a sample size of 15,334 female smokers (18-79 years) were selected. Following data analysis, the odds ratio representing the effects of smoking on FSD was found 1.48 (95%CI: 1.2-1.83), indicating that female smokers were 48% more susceptible to FSD than non-smokers. Also, the publication bias was reported as non-significant (p = 0.178). Since smoking is an increasingly common phenomenon in females and women smokers are 48% more susceptible to the FSD, preparation of necessary health measures by the health policymakers to reduce the number of female smokers and subsequent health services seems necessary.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.