Affiliations 

  • 1 AETs St. John Institute of Pharmacy & Research, Palghar, Maharshtra 401404, India
  • 2 AETs St. John Institute of Pharmacy & Research, Palghar, Maharshtra 401404, India. Electronic address: mohitepb@gmail.com
  • 3 Centre for Global Health Research, Saveetha Medical College and Hospital, Chennai, India; Department of Science and Engineering, Novel Global Community and Educational Foundation, Hebasham, Australia
  • 4 Pharmacology Unit, Jeffrey Cheah School of Medicine and Health Sciences, Monash University, Jalan Lagoon Selatan, Bandar Sunway, 47500 Selangor Darul Ehsan, Malaysia; Center for Transdisciplinary Research, Department of Pharmacology, Saveetha Institute of Medical and Technical Sciences, Saveetha Dental College and Hospital, Saveetha University, Chennai, Tamil Nadu, 600077, India.. Electronic address: subramaniyan.vetriselvan@monash.edu
  • 5 Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, 56000 Cheras, Kuala Lumpur, Malaysia. Electronic address: vinoth@ukm.edu.my
  • 6 Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, Federal University of Health Sciences, Otukpo, Benue State, Nigeria. Electronic address: daniel.uti@fuhso.edu.ng
  • 7 Zoology Department, Faculty of Science, Cairo University, Giza 12613, Egypt
  • 8 Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt
  • 9 Department of Laboratory & Blood Bank, Security Forces Hospital, Mecca, Saudi Arabia
  • 10 Department of Biology, College of Science, King Khalid University, Abha, Saudi Arabia; Department of Zoology, College of Science, Damounhour University, Egypt
  • 11 Department of Biology, College of Science, King Khalid University, Abha, Saudi Arabia
  • 12 Chemistry Department, Preparatory Year Program, Batterjee Medical College, Jeddah 21442, Saudi Arabia
  • 13 Department of Pharmaceutical Sciences, Pharmacy Program, Batterjee Medical College, P.O. Box 6231, Jeddah 21442, Saudi Arabia; Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt
  • 14 Department of Biochemistry, Faculty of Basic Medical Sciences, University of Calabar, Calabar, Nigeria
Biomed Pharmacother, 2024 Jan;170:116083.
PMID: 38163395 DOI: 10.1016/j.biopha.2023.116083

Abstract

As we navigate the modern era, the intersection of time-honoured natural remedies and contemporary scientific approaches forms a burgeoning frontier in global healthcare. For generations, natural products have been foundational to health solutions, serving as the primary healthcare choice for 80% to 85% of the world's population. These herbal-based, nature-derived substances, significant across diverse geographies, necessitate a renewed emphasis on enhancing their quality, efficacy, and safety. In the current century, the advent of biogenic phytonanoparticles has emerged as an innovative therapeutic conduit, perfectly aligning with principles of environmental safety and scientific ingenuity. Utilizing green chemistry techniques, a spectrum of metallic nanoparticles including elements such as copper, silver, iron, zinc, and titanium oxide can be produced with attributes of non-toxicity, sustainability, and economic efficiency. Sophisticated herb-mediated processes yield an array of plant-originated nanomaterials, each demonstrating unique physical, chemical, and biological characteristics. These attributes herald new therapeutic potentials, encompassing antioxidants, anti-aging applications, and more. Modern technology further accelerates the synthesis of natural products within laboratory settings, providing an efficient alternative to conventional isolation methods. The collaboration between traditional wisdom and advanced methodologies now signals a new epoch in healthcare. Here, the augmentation of traditional medicine is realized through rigorous scientific examination. By intertwining ethical considerations, cutting-edge technology, and natural philosophy, the realms of biogenic phytonanoparticles and traditional medicine forge promising pathways for research, development, and healing. The narrative of this seamless integration marks an exciting evolution in healthcare, where the fusion of sustainability and innovation crafts a future filled with endless possibilities for human well-being. The research in the development of metallic nanoparticles is crucial for unlocking their potential in revolutionizing fields such as medicine, catalysis, and electronics, promising groundbreaking applications with enhanced efficiency and tailored functionalities in future technologies. This exploration is essential for harnessing the unique properties of metallic nanoparticles to address pressing challenges and advance innovations across diverse scientific and industrial domains.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.