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The prevalence of bleeding after percutaneous coronary interventions: A systematic review and meta-analysis

Heidary Moghadam R 1 , Mohammadi A 2 , Salari N 3 , Ahmed A 4 , Shohaimi S 5 , Mohammadi M 6

Affiliations 

  • 1 Department of Department of Cardiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address: heidarymoghadam@yahoo.com
  • 2 Medical Biology Research Centre, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address: aidamohammadi2108@gmail.com
  • 3 Department of Biostatistics, School of Health, Sleep Disorders Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address: n_s_514@yahoo.com
  • 4 Department of Department of Cardiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address: sawdager97@yahoo.com
  • 5 Department of Biology, Faculty of Science, University Putra Malaysia, Serdang, Selangor, Malaysia. Electronic address: shmaria@upm.edu.my
  • 6 Cellular and Molecular Research Center, Gerash University of Medical Sciences, Gerash, Iran. Electronic address: Masoud.mohammadi1989@yahoo.com
Indian Heart J, 2024;76(1):16-21.
PMID: 38216122 DOI: 10.1016/j.ihj.2024.01.009

Abstract

BACKGROUND: Bleeding is a common complication associated with percutaneous coronary intervention (PCI). The aim of this study was to determine the prevalence of bleeding after PCI through a systematic review and meta-analysis.

METHODS: The systematic review and meta-analysis covered the period from 1989 to 2023. Multiple databases, including Embase, PubMed, Scopus, Web of Sciences (WoS), MagIran, Scientific Information Database (SID), and Google Scholar, were searched using validated keywords with MeSH and Emtree. The I2 index was used to check for heterogeneity among studies.

RESULTS: The review of 8 studies, with a sample size of 397,298 participants, showed high heterogeneity (I2: 97.8 %). Therefore, the random effects method was used to analyze the results. The prevalence of bleeding after intervention in percutaneous coronary arteries was reported to be 4.4 % (95%CI: 2-9.1).

CONCLUSION: This meta-analysis showed a significant prevalence of bleeding after PCI, highlighting the need for health policymakers to pay more attention to the complications associated with PCI. Interventional cardiologists should consider the effective factors in these bleeding and how to treat and control them due to the importance of this complication.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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