Affiliations 

  • 1 Faculty of Veterinary Medicine, University Putra Malaysia, Serdang, Selangor, 43400, Malaysia
  • 2 National Zoo of Malaysia, Ulu Kelang, Ampang, Selangor, 68000, Malaysia
J. Zoo Wildl. Med., 2013 Dec;44(4):1059-62.
PMID: 24450069

Abstract

A 14-yr-old male puma (Puma concolor) was presented to the veterinary staff of the National Zoo in Malaysia for an auricular mass. Squamous cell carcinoma was diagnosed by histologic examination of a biopsy. Systemic administration of chemotherapy using vincristine (0.5 mg/m2 i.v. q. 7 days for six treatments) and prednisolone (2 mg/kg i.m. q. 72 hr x 7 days) caused side effects of vomiting, weight loss, and alopecia and did not improve the size or appearance of the tumor. Intralesional vincristine injections (0.2 mg q. 7 days for two treatments) and prednisolone (2 mg/kg i.m. q. 72 hr x 15 days) were administered, resulting in complete tumor regression after 14 days of treatment.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.