Haplophytin B from Maclurodendron porteri

Taher M 1 , Susanti D 2 , Abd Hamid S 2 , Edueng K 1 , Jaffri JM 1 , Adina AB 1 Show all authors , Rezali MF 3

Affiliations 

  • 1 Department of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia
  • 2 Department of Chemistry, Faculty of Science, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia
  • 3 SIRIM Berhad (National Metrology Laboratory), Lot PT 4803, Bandar Baru Salak Tinggi, Sepang, Selangor, Malaysia
Pak J Pharm Sci, 2014 Jan;27(1):179-81.
PMID: 24374446

Abstract

An alkaloid from Maclurodendron porteri has been isolated and characterized. Extraction process was conducted by acid-base extraction method followed by column chromatography. The structure was established by nuclear magnetic resonance spectroscopy and mass spectrometry. The compound was identified as haplophytin B which occurs commonly in the Rutaceae family. However, this is the first time this alkaloid was isolated and reported from the species. The compound showed no inhibition against Staphylococus aureus, Pseudomonas aeruginosa, Bacillus cereus and Escherichia coli and no cytotoxic activity against H199 and A549 cell lines.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

MeSH terms
Similar publications