Bioorg Med Chem Lett, 2012 Sep 15;22(18):5780-3.
PMID: 22901897 DOI: 10.1016/j.bmcl.2012.07.101

Abstract

Variation at the 3' position of fluorescein via Suzuki-Miyaura cross-coupling with aryl and heteroaryl moieties gave a family of anthofluoresceins whose spectroscopic properties were studied. The 1-methylindole derivative gave the highest quantum yield and was observed to behave as a molecular rotor, displaying marked variations in fluorescent intensities with viscosity and offering possible application in cellular sensing and fluorescent polarisation assays.

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