Affiliations 

  • 1 Department of Orthopaedics, Traumatology and Rehabilitation, International Islamic University Malaysia, Kuantan, Malaysia
  • 2 Department of Orthopaedics, Hospital Raja Perempuan Zainab II (HRPZII), Kota Bharu, Malaysia
  • 3 Department of Orthopaedics, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia
Malays Orthop J, 2011 Nov;5(3):28-31.
PMID: 25279033 MyJurnal DOI: 10.5704/MOJ.1111.004

Abstract

Langerhans cell histiocytosis of the spine frequently presents as a solitary lesion and rarely results in neurological deficit. Involvement of thyroid tissue is also rare, even in multifocal disease presentations. We present an unusual variant of Langerhans cell histiocytosis in a 37-year-old man presenting with profound quadriparesis and incidental thyroid involvement. MR imaging and skeletal radiographs revealed widespread involvement of the spine. The patient underwent surgical resection of the tumour and stabilization of the spine. Diagnosis was confirmed by histological and immunohistochemistry analysis. Langerhans cell histiocytosis should be included in the differential diagnosis of radiolucent lesions of the spine in adults.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.