Rapid identification of cyclic tetrapyrrolic photosensitisers for photodynamic therapy using on-line hyphenated LC-PDA-MS coupled with photo-cytotoxicity assay

Tan PJ 1 , Appleton DR , Mustafa MR , Lee HB

Affiliations 

  • 1 Cancer Research Initiatives Foundation, Second floor, Outpatient Centre, Sime Darby Medical Centre, 47500, Subang Jaya, Selangor Darul Ehsan, Malaysia
Phytochem Anal, 2012 Jan-Feb;23(1):52-9.
PMID: 21692117 DOI: 10.1002/pca.1324

Abstract

Photodynamic therapy is a treatment modality that involves site-directed generation of cytotoxic reactive oxygen species by light-activated photosensitisers.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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