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Effect of TGF-beta1 antisense oligodeoxynucleotide on renal function in chronic renal failure rats

Hiong LC 1 , Voon KL , Abdullah NA , Sattar MA , Rahman NA , Khan AH Show all authors , Johns EJ

Affiliations 

  • 1 Department of Pharmacology, University of Malaya, Kuala Lumpur 50603, Malaysia
Acta Pharmacol Sin, 2008 Apr;29(4):451-7.
PMID: 18358091 DOI: 10.1111/j.1745-7254.2008.00772.x

Abstract

The aim of the present study was to investigate the effectiveness of transforming growth factor (TGF)-beta1 antisense oligodeoxynucleotides (ODN) in ameliorating deteriorated kidney function in rats with puromycin-induced chronic renal failure (CRF).

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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