Genetic polymorphism of CYP2C8 in three Malaysian ethnics: CYP2C8*2 and CYP2C8*3 are found in Malaysian Indians

Muthiah YD 1 , Lee WL , Teh LK , Ong CE , Ismail R

Affiliations 

  • 1 Pharmacogenetics Study Group, Institute for Research in Molecular Medicine and Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia
J Clin Pharm Ther, 2005 Oct;30(5):487-90.
PMID: 16164496

Abstract

CYP2C8 is genetically polymorphic. Four variants, CYP2C8*2, CYP2C8*3, CYP2C8*4 and CYP2C8*5, which contain mutations in the coding regions have been reported to exhibit different enzyme activity as compared with CYP2C8*1.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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