Affiliations 

  • 1 Institut Pediatrik, Hospital Kuala Lumpur
  • 2 Jabatan Pediatrik UKM, Institut Pediatrik, Hospital Kuala Lumpur, 50586, Jalan Pahang, Kuala Lumpur
  • 3 Jabatan Pediatrik UKM, Institut Pediatrik, Hospital Kuala Lumpur, 50586, Jalan Pahang, Kuala Lumpur
  • 4 Jabatan Radiologi UKM, Institut Pediatrik, Hospital Kuala Lumpur, 50586, Jalan Pahang, Kuala Lumpur
Med J Malaysia, 1997 Dec;52(4):429-32.
PMID: 10968122

Abstract

Interstitial lung disease (ILD) is very rare in children. In the majority of cases the aetiology is unknown. Very little is known about the clinical course of this condition in children. Prognosis may be influenced by sex, age of onset of symptoms, radiographic features, presence of right ventricular hypertrophy and histopathology. We report our experience in managing four children with interstitial lung disease. All these children presented in early infancy with cough, respiratory distress, cyanosis and failure to thrive. Three of these children had finger clubbing and right ventricular hypertrophy. All patients received oral steroids. Chloroquine was added in two patients who showed no response. A trial of oral cyclophosphamide was started in one patient who failed with both drugs. One child is oxygen independent while another is on home oxygen therapy. The other two patients eventually died.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.