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First trimester prenatal diagnosis of beta-thalassaemia following chorionic villus sampling

Chandran R 1 , Ainoon O 2 , Anson I 1 , Anne J 2 , Cheong SK 2

Affiliations 

  • 1 Department of Obstetrics and Gynaecology, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur
  • 2 Department of Pathology, Universiti Kebangsaan Malaysia, Jalan Raia Muda Abdul Aziz, 50300 Kuala Lumpur
Med J Malaysia, 1993 Sep;48(3):341-4.
PMID: 8183149

Abstract

DNA analysis for the diagnosis of beta-thalassaemia is a relatively new technique in Malaysia. This, combined with chorionic villus sampling, has enabled us to offer prenatal diagnosis in the first trimester for this common condition. To the best of our knowledge, this has not hitherto been reported in Malaysia.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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