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Selected metabolites profiling of Orthosiphon stamineus Benth leaves extracts combined with chemometrics analysis and correlation with biological activities

Saidan NH 1 , Hamil MS 2 , Memon AH 3 , Abdelbari MM 4 , Hamdan MR 5 , Mohd KS 6 Show all authors , Majid AM 7 , Ismail Z 8

Affiliations 

  • 1 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, 11800, Pulau Pinang, Malaysia. hafizohsaidan@yahoo.com
  • 2 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, 11800, Pulau Pinang, Malaysia. shahrul.ridzuan18@gmail.com
  • 3 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, 11800, Pulau Pinang, Malaysia. memon_h79@yahoo.com
  • 4 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, 11800, Pulau Pinang, Malaysia. mahamansor69@gmail.com
  • 5 Centre of Drug Research, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, 11800, Pulau Pinang, Malaysia. ikraqlah@gmail.com
  • 6 School of Agriculture and Biotechnology, Faculty of Bioresources and Food Industry, Universiti Sultan Zainal Abidin, Tembila Campus, 22200, Besut, Terengganu, Malaysia. khamsahsuryati@unisza.edu.my
  • 7 Department of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, 11800, Pulau Pinang, Malaysia. aminmalikshah@usm.my
  • 8 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, 11800, Pulau Pinang, Malaysia. zhari@usm.my
BMC Complement Altern Med, 2015;15:350.
PMID: 26446501 DOI: 10.1186/s12906-015-0884-0

Abstract

Studies on selected metabolites profiling of Orthosiphon stamineus extracts using chromatographic and spectroscopic techniques combined with chemometric tools have not been fully elucidated. Thus present study was performed to profile selected metabolites in O. stamineus leaves extracts using HPLC and FTIR combined with chemometric tools and correlated with biological activities.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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