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A novel reverse phase high-performance liquid chromatography method for standardization of Orthosiphon stamineus leaf extracts

Saidan NH 1 , Aisha AF 1 , Hamil MS 1 , Majid AM 2 , Ismail Z 1

Affiliations 

  • 1 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Pulau Pinang, Malaysia
  • 2 Department of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Pulau Pinang, Malaysia
Pharmacognosy Res, 2015 Jan-Mar;7(1):23-31.
PMID: 25598631 DOI: 10.4103/0974-8490.147195

Abstract

Orthosiphon stamineus Benth. (Lamiaceae) is a traditional medicinal plant which has been used in treating various ailments such as kidney diseases, bladder inflammation, arthritis and diabetes. The leaves contain high concentration of phenolic compounds, thus, rosmarinic acid (RA), 3'-hydroxy-5, 6, 7, 4'-tetramethoxyflavone (TMF), sinensetin (SIN) and eupatorin (EUP) were chosen as a marker compounds for standardization of various O. stamineus leaf extracts.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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