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All trans-retinoic acid in the treatment of promyelocytic leukaemia--a case report

Hoe TS 1 , Hussin NH 2 , Chum KW 3 , Cheong SK 4

Affiliations 

  • 1 T S Hoe, MRCP. Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur
  • 2 N H Hussin, DCP. Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur
  • 3 KWChwn, MD. Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur
  • 4 S K Cheong, FSCP. Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur
Med J Malaysia, 1992 Sep;47(3):225-7.
PMID: 1491649

Abstract

A six year old Chinese boy with relapsed Acute Promyelocytic Leukaemia (APML) failed to respond to reinduction with Daunorubicin and Cytarabine infusion. He was successfully treated with all trans-Retinoic Acid (45 mg/m2/day) orally. After four weeks of treatment, he was in complete remission. The side effects of all trans-Retinoic Acid were negligible.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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