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Plasmid-mediated transferable chloramphenicol and tetracycline resistance in Salmonella typhi (Vi phage type 25) isolated in Peninsular Malaysia

Koh CL 1 , Lim ME 2 , Wong YH 3

Affiliations 

  • 1 Chong Lek Koh. Department of Genetics & Cellular Biology, University of Malaya, Kuala Lumpur 22·11. Malaysia
  • 2 Moo Eng Lim. Department of Genetics & Cellular Biology, University of Malaya, Kuala Lumpur 22·11. Malaysia
  • 3 Yuk Heong Wong. Department of Pathology, General Hospital, Kuala Lumpur, Malaysia
Med J Malaysia, 1983 Dec;38(4):320-4.
PMID: 6599991

Abstract

A clinical isolate of Salmonella typhi (Vi phage type 25), resistant to chloramphenicol, streptomycin and tetracycline, was examined for the presence of R plasmids. Results from conjugation, agarose gel electrophoresis and transformation experiments indicated that it harboured a single large self-transmissible R plasmid which coded for both the chloramphenicol and tetracycline resistance traits.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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