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R plasmid-borne transferable multiple antibiotic resistance in a clinical isolate of Proteus sp in Peninsular Malaysia

Koh CL 1 , Tay SH 2

Affiliations 

  • 1 C L Koh, PhD (Lond), DIC, Department of Genetics and Cellular Biology, University of Malaya, Kuala Lumpur 22-11, Malaysia
  • 2 S H Tay, BSc (Hons) (Malaya). Department of Genetics and Cellular Biology, University of Malaya, Kuala Lumpur 22-11, Malaysia
Singapore Med J, 1984 Oct;25(5):300-3.
PMID: 6523137

Abstract

A clinical isolate of Proteus sp., resistant to ampicillin, carbenicillin, cephaloridine, chloramphenicol, cotrimoxazole, gentamicin,
kanamycin and tetracycline, was examined for the presence of conjugative R plasmids. Results from conjugation, agarose gel
electrophoresis and transformation experiments showed that it harboured a large self-transmissible R plasmid which coded for all
the resistance traits.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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