Molecular Epidemiology of Chikungunya Virus by Sequencing

Thayan R 1 , Yusof MA 2 , Saat Z 2 , Sekaran SD 3 , Wang SM 4

Affiliations 

  • 1 Virology Unit, Infectious Diseases Research Centre, Institute for Medical Research, Jalan Pahang, Kuala Lumpur, 50588, Malaysia. rthayan@gmail.com
  • 2 Virology Unit, Infectious Diseases Research Centre, Institute for Medical Research, Jalan Pahang, Kuala Lumpur, 50588, Malaysia
  • 3 Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Jalan Universiti, Kuala Lumpur, 50603, Malaysia
  • 4 Faculty of Medicine, Jalan Hospital, Universiti Teknologi MARA (UiTM), Sungai Buloh Campus, 47000 Sungai Buloh, Selangor Darul Ehsan, Malaysia
Methods Mol Biol, 2016;1426:11-9.
PMID: 27233257 DOI: 10.1007/978-1-4939-3618-2_2

Abstract

Molecular surveillance of Chikungunya virus (CHIKV) is important as it provides data on the circulating CHIKV genotypes in endemic countries and enabling activation of measures to be taken in the event of a pending outbreak. Molecular surveillance is carried out by first detecting CHIKV in susceptible humans or among field-caught mosquitoes. This is followed by sequencing a selected region of the virus which will provide evidence on the source of the virus and possible association of the virus to increased cases of Chikungunya infections.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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