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A simple, high-throughput, colourimetric, field applicable loop-mediated isothermal amplification (HtLAMP) assay for malaria elimination

Britton S 1 , Cheng Q 2 , Sutherland CJ 3 , McCarthy JS 4

Affiliations 

  • 1 University of Queensland, Brisbane, Australia. sumudu.britton@qimrberghofer.edu.au
  • 2 Australian Army Malaria Institute, Brisbane, Australia. Qin.Cheng@defence.gov.au
  • 3 London School of Hygiene and Tropical Medicine, London, UK. colin.sutherland@lshtm.ac.uk
  • 4 University of Queensland, Brisbane, Australia. j.mccarthy@uq.edu.au
Malar J, 2015;14:335.
PMID: 26315027 DOI: 10.1186/s12936-015-0848-3

Abstract

To detect all malaria infections in elimination settings sensitive, high throughput and field deployable diagnostic tools are required. Loop-mediated isothermal amplification (LAMP) represents a possible field-applicable molecular diagnostic tool. However, current LAMP platforms are limited by their capacity for high throughput.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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