A cross-sectional study of 71 laboratory technicians in Ministry of Health Malaysia (MOH) Hospitals (response rate 89.9%) was conducted from September ZOO1 till February 2002. Seven MOH Hospitals in Kelantan were chosen. Karase job Content — Questionnaire (Malay Version) was used as research instrument in this study. There were five scales in the questionnaire; two scales were used to dehne job strain - decision latitude and psychological demands. Results showed that the majority of laboratory technicians in MOH Hospitah were classified as passive. However, the proportion of high strain group was the second highest after passive group. The percentage of laboratory technicians in MOH Hospitals which was classified as having a high job strain was 26.8%. The “high strain" group scored significantly higher for hazardous conditions, toxic exposures, total psychological stressors, total physical hazard, and total physical stressors as compared to the “non»high strain” group. Laboratory technicians in “high strain" group had significantly younger in age (18-34 years) group (42.1%) compared to those in “non·high strain" group (7.7%) and shorter total duration of employment (yr) ( 15 .3 x 6.8) compared to those in “non»high strain" group (19.2 x 6.7). We therefore conclude that less experienced and higher psychosocial factors at work experiencing higher job strain compared to those who were more experienced and less psychosocial factors.