This paper discuss thermal comfort studies of an under air conditioning in hot and humid climate which at one of the higher institution in East Coast of Malaysia. Indoor thermal environment is important as it affects the health and productivity of building occupants. The paper reports on an experimental investigation of indoor thermal comfort characteristics under the control of air conditioning. Firstly, the well known Fanger’s thermal comfort model was simplified for the current experimental investigation. This is followed by reporting the experimental results of indoor thermal comfort characteristics under the control of temperature, with eight different of temperatures which are 22oC to 29oC. Finally, indoor thermal comfort was merely affected by the increment ventilation and outdoor climate. PMV value was higher when near from the window because of the effects of the wall radiations and the metabolic heat.