Affiliations 

  • 1 Institute for Medical Research
  • 2 Universiti Kebangsaan Malaysia
MyJurnal

Abstract

The objectives of this study is to evaluate subjective symptoms and neurobehavioral performances among workers exposed to lead and its relation with blood lead levels. The methodology of this study was restricted to 141 Malaysian battery manufacturing factories male workers with mean (SD) age of 35.2 (9.6) years, years of employment 9.1 (7.1), current blood lead concentration 40.5 (16.8) μg/dl were given WHO neurobehavioral core test battery. Results showed that highly exposed group blood lead level (high ≥ 40 μg/dl) performed less well in 4 of 13 responses reported higher subjective symptoms of weakness of lower limbs and anorexia. Significant correlation was found between blood lead and Digit Symbol, Digit Forward, Digit Backward, Aiming Pursuit Test and Trail B. Regression analysis showed reduction in cognitive, memory and concentration functions at ≤ 30 μg/dl blood lead levels with maximum lead effect at Digit symbol’s score at 40 μg/dl. In conclusion, this study is consistent with the larger body of neurobehavioral tests in lead exposure and has proven the ability of these tests in detecting low level of lead toxicity.