Tamoxifen Suppresses the Growth of Malignant Pleural Mesothelioma Cells

Jennings CJ 1 , Zainal N 1 , Dahlan IM 1 , Kay EW 2 , Harvey BJ 1 , Thomas W 3

Affiliations 

  • 1 Department of Molecular Medicine, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland
  • 2 Department of Histopathology, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland
  • 3 Department of Molecular Medicine, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland warren.thomas@perdanauniversity.edu.my
Anticancer Res, 2016 11;36(11):5905-5913.
PMID: 27793915

Abstract

Malignant pleural mesothelioma (MPM) is a rare but highly aggressive malignancy most often associated with exposure to asbestos. Recent evidence points to oestrogen receptor (ER)-β having a tumour-suppressor role in MPM progression, and this raises the question of whether selective modulators of ERs could play a role in augmenting MPM therapy.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

MeSH terms
Similar publications