Mechanistic insights into acyclovir-polyethylene glycol 20000 binary dispersions

Venkateskumar K 1 , Parasuraman S 2 , Gunasunderi R 3 , Sureshkumar K 4 , Nayak MM 5 , Shah SA 6 Show all authors , Kassen K 1 , Kai HW 1

Affiliations 

  • 1 Unit of Pharmaceutical Technology, Faculty of Pharmacy, AIMST University, Semeling 08100, Malaysia
  • 2 Unit of Pharmacology, Faculty of Pharmacy, AIMST University, Semeling 08100, Malaysia
  • 3 Colloid Interface Science Centre, Centre of Excellence, Malaysian Rubber Board, Experiment Station, Sungai Buloh, Selangor DE, Malaysia
  • 4 KMCH College of Pharmacy, Coimbatore, Tamil Nadu, India
  • 5 Spectroscopy Analytical Test Facility, Indian Institute of Science, Bengaluru, Karnataka, India
  • 6 Faculty of Pharmacy, Universiti Teknologi Mara, Puncak Alam Campus, Selangor, Dahrul Ehsan, Malaysia
Int J Pharm Investig, 2016 Oct-Dec;6(4):194-200.
PMID: 28123988 DOI: 10.4103/2230-973X.195925

Abstract

The objective of this study is to provide a mechanistic insight into solubility enhancement and dissolution of acyclovir (ACY) by polyethylene glycol20000 (PEG20000).

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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