Affiliations 

  • 1 Basic Sciences and Oral Biology Unit, School of Dental Sciences, USM Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia
J Oral Biol Craniofac Res, 2017 10 19;8(1):48-53.
PMID: 29556464 DOI: 10.1016/j.jobcr.2017.10.003

Abstract

Manipulation of dental stem cells (DSCs) using current technologies in tissue engineering unveil promising prospect in regenerative medicine. DSCs have shown to possess angiogenic and osteogenic potential in both in vivo and in vitro. Neural crest derived DSCs can successfully be isolated from various dental tissues, exploiting their intrinsic great differentiation potential. In this article, researcher team intent to review the characteristics of DSCs, with focus on their angiogenic and osteogenic differentiation lineage. Clinical data on DSCs are still lacking to prove their restorative abilities despite extensive contemporary literature, warranting research to further validate their application for bone tissue engineering.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.