Affiliations 

  • 1 Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore Brenda_Ang@ttsh.com.sg
  • 2 Department of Neuroradiology, National Neuroscience Institute, Singapore
  • 3 Programme in Emerging Infectious Disease, Duke-NUS Medical School, Singapore
J Clin Microbiol, 2018 06;56(6).
PMID: 29643201 DOI: 10.1128/JCM.01875-17

Abstract

Nipah virus, a paramyxovirus related to Hendra virus, first emerged in Malaysia in 1998. Clinical presentation ranges from asymptomatic infection to fatal encephalitis. Malaysia has had no more cases since 1999, but outbreaks continue to occur in Bangladesh and India. In the Malaysia-Singapore outbreak, transmission occurred primarily through contact with pigs, whereas in Bangladesh and India, it is associated with ingestion of contaminated date palm sap and human-to-human transmission. Bats are the main reservoir for this virus, which can cause disease in humans and animals. There are currently no effective therapeutics, and supportive care and prevention are the mainstays of management.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.