Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2016-2018)

Breadmore MC 1 , Grochocki W 1 , Kalsoom U 1 , Alves MN 1 , Phung SC 1 , Rokh MT 2 Show all authors , Cabot JM 1 , Ghiasvand A 1 , Li F 1 , Shallan AI 3 , Keyon ASA 4 , Alhusban AA 5 , See HH 4 , Wuethrich A 6 , Dawod M 7 , Quirino JP 1

Affiliations 

  • 1 Australian Centre for Research on Separation Science, Chemistry, School of Natural Science, University of Tasmania, Hobart, Tasmania, Australia
  • 2 Trajan Scientific and Medical, Ringwood, VIC, Australia
  • 3 Future Industries Institute (FII), University of South Australia, Mawson Lakes, Australia
  • 4 Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, Johor Bahru, Johor, Malaysia
  • 5 Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
  • 6 Centre for Personalized Nanomedicine, Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD, Australia
  • 7 Department of Chemistry, University of Michigan, Ann Arbor, MI, USA
Electrophoresis, 2019 01;40(1):17-39.
PMID: 30362581 DOI: 10.1002/elps.201800384

Abstract

One of the most cited limitations of capillary and microchip electrophoresis is the poor sensitivity. This review continues to update this series of biannual reviews, first published in Electrophoresis in 2007, on developments in the field of online/in-line concentration methods in capillaries and microchips, covering the period July 2016-June 2018. It includes developments in the field of stacking, covering all methods from field-amplified sample stacking and large-volume sample stacking, through to isotachophoresis, dynamic pH junction, and sweeping. Attention is also given to online or in-line extraction methods that have been used for electrophoresis.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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