The importance of epidemiology and epidemilogical knowledge of plantation health and disease in the planning of health care & effective management of a plantation is highlighted. The results of the survey of endemic diseases in the estates in Peninsular Malaysia are presented and compared with national disease patterns. The disease patterns in the plantations are similar to those for the country in general. Differences that exist are due to differences in the ecology of the plantations. The health effects of ecological changes consequent on development and progress are referred to. Most of the endemic communicable diseases encountered in the plantations can be prevented and controlled through the improvement of the micro environment of the plantations and the utilisation of simple available appropriate technologies for health care and services.