Affiliations 

  • 1 Centre for Drug Research, Universiti Sains Malaysia, Minden, Penang, Malaysia
  • 2 School of Social Sciences, Universiti Sains Malaysia, Minden, Penang, Malaysia
  • 3 Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, USA
  • 4 Department of Emergency Medicine, Brigham and Women's Hospital, Harvard Medical School. U.S, Boston, MA, USA
J Psychoactive Drugs, 2019 06 20;52(1):86-92.
PMID: 31218929 DOI: 10.1080/02791072.2019.1632505

Abstract

The leaves from Mitragyna speciosa (Korth.) trees, also known as kratom, are traditionally used in Southeast Asia as a mild psychotropic agent. We investigated the demographic characteristics of persons who used both kratom cocktail and benzodiazepines (BZO) in a sample drawn from a rural area in Penang, Malaysia, and the reasons for BZO use. Seventy-seven participants who currently use a kratom cocktail along with BZO were recruited through snowball sampling for this cross-sectional study. The participants were male, and the majority were Malays (99%, n = 76/77), single (57%, n = 44/77) and employed (91%, n = 70/77). BZO was used with kratom cocktail 1) to increase euphoria; 2) to reduce dependence on methamphetamine; 3) to promote sleep; 4) to ease methamphetamine-associated psychological symptoms and 5) to decrease the craving for kratom. There were no significant differences in the intake of kratom use (p = .751), BZO use duration (p = .259), frequency (p = .188) and quantity (p = .888) of BZO use in the last 7 days, and quantity of BZO use in the last 30 days (p = .337) between kratom users and kratom poly-drug users. An awareness of the health consequences of the co-use of kratom with BZO is needed to prevent untoward health incidents.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.