Affiliations 

  • 1 Faculty of Medicine, Universiti Kuala Lumpur Royal College of Medicine Perak, Perak, Malaysia
  • 2 Department of Pathology, Hospital Raja Permaisuri Bainun, Perak, Malaysia
  • 3 Department of Dermatology, Hospital Raja Permaisuri Bainun, Perak, Malaysia
Oman Med J, 2019 Jul;34(4):345-349.
PMID: 31360325 DOI: 10.5001/omj.2019.67

Abstract

Eosinophilic granulomatosis with polyangiitis (formerly known as Churg-Strauss syndrome) is a rare vasculitis in children. It commonly presents with respiratory symptoms, especially asthma, allergic rhinitis, and peripheral eosinophilia. Involvement of other systems, such as renal and cardiac, may carry a poor prognosis. Anti-neutrophil cytoplasmic antibodies have been found less frequently in children with this condition. We report a case of a 15-year-old male who presented with indurated and pruritic papules on both legs and peripheral eosinophilia without other system involvement. Histopathological findings from a skin biopsy were suggestive of eosinophilic granulomatosis with polyangiitis. Anti-neutrophil cytoplasmic antibodies were negative.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.