Affiliations 

  • 1 Sport Innovation and Technology Center (SITC), Universiti Teknologi MalaysiaJ, Johor, Malaysia. Electronic address: ardi@mail.fkm.utm.my
  • 2 Medical Device Technology Group, Faculty of Biomedical Engineering and Health Science, Universiti Teknologi Malaysia, Johor, Malaysia
  • 3 Sport Innovation and Technology Center (SITC), Universiti Teknologi MalaysiaJ, Johor, Malaysia
  • 4 Griffith School of Engineering, Griffith University, Australia
Med Eng Phys, 2015 Jan;37(1):77-86.
PMID: 25523865 DOI: 10.1016/j.medengphy.2014.11.001

Abstract

Artificial bone is a suitable alternative to autografts and allografts, however their use is still limited. Though there were numerous reports on their structural properties, permeability studies of artificial bones were comparably scarce. This study focused on the development of idealised, structured models of artificial cancellous bone and compared their permeability values with bone surface area and porosity. Cancellous bones from fresh bovine femur were extracted and cleaned following an established protocol. The samples were scanned using micro-computed tomography (μCT) and three-dimensional models of the cancellous bones were reconstructed for morphology study. Seven idealised and structured cancellous bone models were then developed and fabricated via rapid prototyping technique. A test-rig was developed and permeability tests were performed on the artificial and real cancellous bones. The results showed a linear correlation between the permeability and the porosity as well as the bone surface area. The plate-like idealised structure showed a similar value of permeability to the real cancellous bones.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.