Method for Evaluating Neuromodulatory Properties of Dental Pulp Stem Cell as an In Vitro Model for Parkinson's Disease

Gnanasegaran N 1 , Thimiri Govinda Raj DB 2 , Arumugam S 3

Affiliations 

  • 1 Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore. naresh_waran@outlook.com
  • 2 Envirotransgene Biosolutions Global, Chennai, India
  • 3 School of Bio Sciences and Technology (SBST), VIT University, Vellore, Tamil Nadu, India
Methods Mol Biol, 2020;2125:193-196.
PMID: 31489601 DOI: 10.1007/7651_2019_261

Abstract

Several research groups have utilized dental pulp stem cells for numerous studies as treatment modality for Parkinson's disease (PD). However, the roles of dental pulp stem cells in governing the Parkinson's disease inflammatory microenvironment remain to be evaluated. In this article, we elaborate the method where we can investigate the effects of dental pulp stem cells on neurons and microglia in an in vitro inflammatory microenvironment.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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