A new cycloartane triterpene bisdesmoside from the rhizomes of Actaea vaginata

Zhang M 1 , Yang Q 2 , Zhang X 1 , Wu H 2

Affiliations 

  • 1 College of Medicine, Xi'an International University, Xi'an, P.R. China
  • 2 Beijing Key Laboratory of New Drug Discovery based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China
Nat Prod Res, 2021 Oct;35(20):3426-3431.
PMID: 31821060 DOI: 10.1080/14786419.2019.1700509

Abstract

A new cycloartane triterpene bisdesmoside, soulieoside T (1), and one known compound, oleanolic acid (2), were isolated from the ethanolic extract of the rhizomes of Actaea vaginata. Their structures were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compound 1 was evaluated for cytotoxic activities against three human cancer cell lines.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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