Affiliations 

  • 1 Senior researcher of department of prevention & treatment of emergency conditions, "LT Malaya Therapy National Institute NAMSU", 2A Liubovi Maloy av., Kharkiv 61039, Ukraine
  • 2 Chief of Department of prevention & treatment of emergency conditions, "LT Malaya Therapy National Institute NAMSU", 2A Liubovi Maloy av., Kharkiv 61039, Ukraine
  • 3 Senior Consultant of Therapeutic Unit, Internal Medicine Department, State Medical University of Zaporozhye, 26, Mayakovsky av., Zaporozhye UA-69035, Ukraine
  • 4 Senior Staff of the Department of Clinical, Social & Child Psychiatry of the State Institution "Institute of Neurology, Psychiatry & Narcology of The National Academy of Medical Sciences of Ukraine", Assistant of The Department of Clinical Neurology, Psychiatry & Narcology of V. N. Karazin's Kharkiv National University, Kharkiv, Ukraine
Future Cardiol, 2020 09;16(5):457-467.
PMID: 32508125 DOI: 10.2217/fca-2019-0082

Abstract

Aim: To investigate associations between subclinical distress and 6-month clinical outcomes after ST-segment elevation myocardial infarction (STEMI). Materials & methods: The case-control study involved 144 STEMI patients (72 STEMI having subclinical emotional disturbances were included to the case group and 72 STEMI individuals matched with age, sex and cardiovascular risk factors were enrolled to the control group). The primary end point was the combination of 6-month events including CV death, recurrent angina, newly diagnosed heart failure and re-hospitalization. Results: The emotional distress predicted out-hospital combined end point (odds ratio [OR] = 2.48; 95% CI: 1.12-5.33; p = 0.034). Other independent predictors of out-hospital end point were Type 2 diabetes mellitus (OR = 1.10; 95% CI: 1.02-1.23; p = 0.048), thrombolysis in myocardial infarction score <6 units (OR = 0.86; 95% CI: 0.67-0.92; p = 0.001) and the number of culprit vessels (OR = 1.19; 95% CI: 1.02-1.34; p = 0.002). Conclusion: Premorbid emotional distress independently predicted 6 month combined clinical end point in STEMI patients.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.