Affiliations 

  • 1 Endocrinology Unit, Department of Medicine, Universiti Putra Malaysia
  • 2 Endocrinology Unit, Department of Medicine, Pusat Perubatan Universiti Kebangsaan Malaysia
  • 3 Radiology Department, Pusat Perubatan Universiti Kebangsaan Malaysia
J ASEAN Fed Endocr Soc, 2018;33(1):49-52.
PMID: 33442110 DOI: 10.15605/jafes.033.01.08

Abstract

We present the rare case of a 47-year-old woman with protracted primary hyperparathyroidism complicated by communicating hydrocephalus and cerebellar tonsillar herniation secondary to calvarial thickening. The parathyroid glands remained elusive, despite the use of advanced preoperative imaging modalities and three neck explorations. The serum calcium was optimally controlled with cinacalcet and alfacalcidol. Awareness of this rare complication is essential for early diagnosis and prompt intervention to prevent fatal posterior brain herniation.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.